10 Result(s)
within
**aoxiao Sun
Life Sciences
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Article
Angiogenin-mediated tsRNAs control inflammation and metabolic disorder by regulating NLRP3 inflammasome
The cellular stress response system in immune cells plays a crucial role in regulating the development of inflammatory diseases. In response to cellular damage or microbial infection, the assembly of the NLRP3...
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Article
Open AccessSelenium Concentration Is Positively Associated with Triglyceride-Glucose Index and Triglyceride Glucose-Body Mass Index in Adults: Data from NHANES 2011–2018
Compiling evidence supports that selenium plays a vital role in glucose metabolism. Triglyceride-glucose index (TyG) and triglyceride-glucose-body mass index (TyG-BMI) are commonly used in epidemiologic studie...
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Open AccessDifferential toxicity to murine small and large intestinal epithelium induced by oncology drugs
Gastrointestinal toxicity is a major concern in the development of drugs. Here, we establish the ability to use murine small and large intestine-derived monolayers to screen drugs for toxicity. As a proof-of-c...
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Genetic dissection of wheat panicle traits using linkage analysis and a genome-wide association study
Coincident regions on chromosome 4B for GW, on 5A for SD and TSS, and on 3A for SL and GNS were detected through an integration of a linkage analysis and a genome-wide association study (GWAS). In addition, si...
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Open AccessEffect of the epiphytic bacterium Bacillus sp. WPySW2 on the metabolism of Pyropia haitanensis
A variety of different symbiotic microbial communities are harbored on the surface of seaweeds, the interactions of which depend upon nutritional exchanges between the microbes and the hosts. Metabolomic profi...
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Genetic Dissection of Wheat Kernel Hardness Using Conditional QTL Map** of Kernel Size and Protein-Related Traits
Kernel hardness (KH) is one of the primary quality parameters for common wheat (Triticum aestivum L.) and has a major impact on milling, flour quality, and end-product properties. In addition to Puroindoline (Pin
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Article
Open AccessSynergistic effect of a novel autophagy inhibitor and Quizartinib enhances cancer cell death
Drug combinations have been increasingly applied in chemotherapy as a strategy to enhance the efficacy of anti-cancer treatment. The appropriate drug combinations may achieve synergistic effects beyond monothe...
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Article
Design and one-pot synthesis of 2-thiazolylhydrazone derivatives as influenza neuraminidase inhibitors
Two series of novel 2-thiazolylhydrazone derivatives were designed and synthesized via one-pot reaction of benzaldehyde derivatives, $...
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Article
Open AccessStatistical inference for time course RNA-Seq data using a negative binomial mixed-effect model
Accurate identification of differentially expressed (DE) genes in time course RNA-Seq data is crucial for understanding the dynamics of transcriptional regulatory network. However, most of the available method...
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BMP9 inhibits the bone metastasis of breast cancer cells by downregulating CCN2 (connective tissue growth factor, CTGF) expression
Bone morphogenetic proteins (BMPs), which belong to the transforming growth factor-β superfamily, regulate a wide range of cellular responses including cell proliferation, differentiation, adhesion, migration,...
