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Article
Solvent-dependence of KI Mediated Electrosynthesis of Imidazo[1,2-a]pyridines
Iodized salts are widely used as mediators to promote C-H functionalization. Solvents and additives have been described as significant roles in these reactions. However, the further electrochemical investigati...
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Article
Design, synthesis and neuraminidase inhibitory activity of 4-methyl-5-(3-phenylacryloyl) thiazoles
A series of 4-methyl-5-(3-phenylacryloyl)thiazoles based on chalcones were designed, synthesized and evaluated for their influenza neuraminidase (NA) inhibitory activity in vitro. A preliminary structure–activ...
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Article
Open AccessCRNDE enhances the expression of MCM5 and proliferation in acute myeloid leukemia KG-1a cells by sponging miR-136-5p
The long-noncoding RNA colorectal neoplasia differentially expressed (CRNDE) gene has been considered to be crucial in tumor malignancy. Although CRNDE is highly expressed in acute myeloid leukemia (AML), its ...
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Chapter and Conference Paper
Liquid Metal-Enabled Soft Actuators for Untethered Manipulation
Recently, the newly emerging soft robotics has attracted extensive interest because of its flexible actuating strategies, compatibility for various working occasions, and safe interaction with humans. Among th...
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Article
Open AccessFrom twisting to settling down as a nurse in China: a qualitative study of the commitment to nursing as a career
The nurse workforce shortage, partially caused by high work turnover, is an important factor influencing the quality of patient care. Because previous studies concerning Chinese nurse work turnover were predom...
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Article
Open AccessGSK-J4 induces cell cycle arrest and apoptosis via ER stress and the synergism between GSK-J4 and decitabine in acute myeloid leukemia KG-1a cells
GSK-J4 is the inhibitor of H3K27me3 demethylase. Recent studies demonstrated that GSK-J4 could affect the proliferation and apoptosis of a variety of cancer cells. However, the effects and underlying mechanism...
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Chapter and Conference Paper
Design and Operation Recommendations for Shared BRT Stops with No Overtaking
In some BRT systems, certain sections of the operating infrastructure are shared with conventional buses. With increases in arrival rates and the occurrence of a phenomenon known as in-stop queueing, service q...
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Article
Design, synthesis, bioactivity, and DFT calculation of 2-thiazolyl-hydrazone derivatives as influenza neuraminidase inhibitors
Three series of thiazolylhydrazone derivatives were designed, synthesized, and evaluated for their neuraminidase (NA) inhibitory activity against influenza virus H1N1 in vitro. Compounds 1 and 2 were synthesized ...
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Article
Synthesis of Chalcone Derivatives Containing Furan or/and Pyran Ring as Neuraminidase Inhibitors
Twenty-seven novel chalcone derivatives were designed and synthesized as neuraminidase(NA) inhibitors. A concise suitable synthetic strategy was employed in the target compounds’ synthesis with relatively high...
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Article
Microwave-assisted synthesis, characterization and bioassay of acylhydrazone derivatives as influenza neuraminidase inhibitors
A series of acylhydrazone derivatives (4a–4s) were synthesized via microwave irradiation with short reaction time and good yields. The crystal structure of compound 4j was further determined by single-crystal X-r...
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Article
Synthesis and antitumor activity of novel N-(5-benzyl-4-(tert-butyl)thiazol-2-yl)-2-(piperazin-1-yl)acetamides
A series of novel N-(5-benzyl-4-(tert-butyl) thiazol-2-yl)-2-(piperazin-1-yl)acetamides were designed, synthesized and evaluated for their antitumor activities in vitro. The structures of the synthesized compound...
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Article
Design and one-pot synthesis of 2-thiazolylhydrazone derivatives as influenza neuraminidase inhibitors
Two series of novel 2-thiazolylhydrazone derivatives were designed and synthesized via one-pot reaction of benzaldehyde derivatives, $...
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Article
Synthesis and herbicidal activity of N-(2,2-dimethyl-7-alkoxy-2,3-dihydrobenzofuran-5-yl)-2-(4-arylxoyphenoxy)propionamides
In order to find novel herbicidal active compounds, a series of N-(2,2-dimethyl-7-alkoxy-2,3-dihydro-benzofuran-5-yl)-2-(4-arylxoyphenoxy)propionamides was designed, prepared and evaluated for their herbicidal ac...
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Article
Syntheses and fungicidal activities of thiazole-5-carboxanilides bearing thioether group
In an attempt to find leading thiazole carboxanilides exhibiting fungicidal activities, we designed and synthesized a new series of 2-sulfursubstituted thiazole carboxanilides via the reaction between 2-sulfur...
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Article
Synthesis and fungicidal activity of some novel thiazole Schiff bases derived from benzo[d][1,3]dioxole
A series of novel thiazole Schiff base derivatives containing benzo[d][1,3]dioxole moiety was designed, synthesized and screened for their fungicidal activities. The preliminary results demonstrated that compound...
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Article
Design, synthesis and neuraminidase inhibitory activity of N-(5-benzyl-4-(tert-butyl)thiazol-2-yl)benzamides
A series of N-(5-benzyl-4-(tert-butyl)thiazol-2-yl)benzamides were synthesized and the structures were characterized by 1H NMR, MS and elemental analyses. The crystal structures of compounds F5 and F16 were deter...
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Chapter and Conference Paper
A Novel Terrain Rending Method for Visual Navigation
Compared with the traditional 2D electronic map navigation, the visual navigation has large amount of data. Especially when the viewpoint changes with high speed, navigation devices can’t display smoothly. Bas...
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Article
Synthesis and antitumor activity of 4-tert-butyl-5-benzyl-2-benzyliminothiazoles
A series of novel Schiff bases including 4-tert-butyl-5-benzyl-2-benzyliminothiazoles was synthesized by reacting the aromatic aldehydes with the corresponding 2-aminothiazoles. The antitumor bioassay revealed th...
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Chapter and Conference Paper
The Study of Soil Fertility Spatial Variation Feature Based on GIS and Data Mining
Studying on the spatial distribution and variation characteristics of soil fertility by Application of geographical information systems (GIS) and data mining(DM), with the quantitative analysis of spatial vari...
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Article
Synthesis and Crystal Structure of 2-Amino-4-(4-hydroxyphenyl)-5-propylthiazole Ethanol Solvate 0.25 Hydrate
2-Amino-4-(4-hydroxyphenyl)-5-propylthiazole was synthesized by the reaction of α-bromo-1-(4-hydroxyphenyl)-1-pentone with thiourea. The crystal structure of its ethanol solvate 0.25 hydrate, C12H14N2OS···C2H5OH·...
