-
Article
Research on Digital Transformation Driving the High-Quality Development of Cultural and Tourism Enterprises—Evidence Based on Listed Cultural and Tourism Companies
Digital transformation has become an important means for cultural and tourism enterprises to achieve high-quality development. The role of digital transformation in driving the development of cultural and tour...
-
Article
Metabolic lactate production coordinates vasculature development and progenitor behavior in the develo** mouse neocortex
Proper neural progenitor behavior in conjunction with orderly vasculature formation is fundamental to the development of the neocortex. However, the mechanisms coordinating neural progenitor behavior and vesse...
-
Article
Production of bioactive recombinant human fibroblast growth factor 12 using a new transient expression vector in E. coli and its neuroprotective effects
In recent years, an increasing number of studies have shown that fibroblast growth factor 12 (FGF12) plays important roles in regulating neural development and function. Importantly, changes of FGF12 expressio...
-
Article
Chronic PFOS Exposure Disrupts Thyroid Structure and Function in Zebrafish
Perfluorooctane sulfonic acid (PFOS), as a potential endocrine disrupting chemical, is widely detected in the environment, wildlife and human. Currently few studies have documented the effects of chronic PFOS ...
-
Article
Engineering rTCA pathway and C4-dicarboxylate transporter for l-malic acid production
l-Malic acid is an important component of a vast array of food additives, antioxidants, disincrustants, pharmaceuticals, and cosmetics. Here, we presented a pathway optimization strategy ...
-
Article
A Study on Environmental Bisphenol A Pollution in Plastics Industry Areas
Bisphenol A (BPA), a well-known endocrine-disrupting chemical, is receiving increasing concerns regarding its adverse effects on the endocrine system in wildlife and humans. This study was designed to investig...
-
Article
Open AccessSubchronic perfluorooctanesulfonate (PFOS) exposure induces elevated mutant frequency in an in vivo λ transgenic medaka mutation assay
Perfluorooctanesulfonate (PFOS) has been widely detected in the environment, wildlife and humans, but few studies have ever examined its mutagenic effect in vivo. In the present study, we use a transgenic fish mo...
-
Article
Open AccessCharacterization of mammary epithelial stem/progenitor cells and their changes with aging in common marmosets
Age is the number one risk factor for breast cancer, yet the underlying mechanisms are unexplored. Age-associated mammary stem cell (MaSC) dysfunction is thought to play an important role in breast cancer carc...
-
Article
Open AccessMurine mammary stem/progenitor cell isolation: Different method matters?
Murine mammary stem/progenitor cell isolation has been routinely used in many laboratories, yet direct comparison among different methods is lacking. In this study, we compared two frequently used digestion me...
-
Article
The dynamics of murine mammary stem/progenitor cells
The stem/progenitor cells in the murine mammary gland are a highly dynamic population of cells that are responsible for ductal elongation in puberty, homeostasis maintenance in adult, and lobulo-alveolar genes...
-
Protocol
Stem/Progenitor Cells in Murine Mammary Gland: Isolation and Functional Characterization
The presence of adult functional mammary epithelial stem/progenitor cells in mammary gland and recent identification of enriched fraction of transplantable mammary stem cells (MaSCs) through specific cell surf...
-
Article
Chronic zebrafish low dose decabrominated diphenyl ether (BDE-209) exposure affected parental gonad development and locomotion in F1 offspring
Polybrominated diphenyl ethers (PBDEs) are widely used as flame retardants around the world. Because of large production volumes, widespread usage and persistence, PBDEs are now ubiquitous environmental pollut...
-
Article
Determination of Estrone and 17β-Estradiol in Water Samples Using Dispersive Liquid–Liquid Microextraction Followed by LC
A new method, termed dispersive liquid–liquid microextraction (DLLME), was developed for the extraction and pre-concentration of estrone (E1) and 17β-estradiol (E2) in water samples. The samples were extracted...
-
Article
Fixation methods can produce misleading artifacts in sperm cell ultrastructure of diploid and tetraploid Pacific oysters, Crassostrea gigas
Spermatozoa from diploid and tetraploid Pacific oysters (Crassostrea gigas) were examined after anisotonic fixation. Morphological anomalies, such as membrane rupture, detached tails, and the formation of tail ve...
