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    Article

    Chronic PFOS Exposure Disrupts Thyroid Structure and Function in Zebrafish

    Perfluorooctane sulfonic acid (PFOS), as a potential endocrine disrupting chemical, is widely detected in the environment, wildlife and human. Currently few studies have documented the effects of chronic PFOS ...

    Jiangfei Chen, Lidan Zheng, Linjie Tian in Bulletin of Environmental Contamination an… (2018)

  2. Article

    Open Access

    Subchronic perfluorooctanesulfonate (PFOS) exposure induces elevated mutant frequency in an in vivo λ transgenic medaka mutation assay

    Perfluorooctanesulfonate (PFOS) has been widely detected in the environment, wildlife and humans, but few studies have ever examined its mutagenic effect in vivo. In the present study, we use a transgenic fish mo...

    Yuanhong Chen, Wei Hu, Changjiang Huang, Shushan Hua, Qihao Wei in Scientific Reports (2016)

  3. Article

    Open Access

    Dichlorvos exposure results in large scale disruption of energy metabolism in the liver of the zebrafish, Danio rerio

    Exposure to dichlorvos (DDVP), an organophosphorus pesticide, is known to result in neurotoxicity as well as other metabolic perturbations. However, the molecular causes of DDVP toxicity are poorly understood,...

    Tri M. Bui-Nguyen, Christine E. Baer, John A. Lewis, Dongren Yang in BMC Genomics (2015)

  4. Article

    Open Access

    Ontogeny of biochemical, morphological and functional parameters of synaptogenesis in primary cultures of rat hippocampal and cortical neurons

    Synaptogenesis is a critical neurodevelopmental process whereby pre- and postsynaptic neurons form apposed sites of contact specialized for chemical neurotransmission. Many neurodevelopmental disorders are tho...

    Joshua A Harrill, Hao Chen, Karin M Streifel, Dongren Yang in Molecular Brain (2015)

  5. No Access

    Article

    Chronic zebrafish low dose decabrominated diphenyl ether (BDE-209) exposure affected parental gonad development and locomotion in F1 offspring

    Polybrominated diphenyl ethers (PBDEs) are widely used as flame retardants around the world. Because of large production volumes, widespread usage and persistence, PBDEs are now ubiquitous environmental pollut...

    Jianhui He, Dongren Yang, Chunyan Wang, Wei Liu, Junhua Liao, Tao Xu in Ecotoxicology (2011)