293 Result(s)
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Open AccessUnveiling the translational dynamics of lychee (Litchi chinesis Sonn.) in response to cold stress
Cold stress poses a significant threat to the quality and productivity of lychee (Litchi chinensis Sonn.). While previous research has extensively explored the genomic and transcriptomic responses to cold stress ...
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Distinct roles of H3K27me3 and H3K36me3 in vernalization response, maintenance, and resetting in winter wheat
Winter plants rely on vernalization, a crucial process for adapting to cold conditions and ensuring successful reproduction. However, understanding the role of histone modifications in guiding the vernalizatio...
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Open AccessSmall extracellular vesicles derived from microRNA-22-3p-overexpressing mesenchymal stem cells protect retinal ganglion cells by regulating MAPK pathway
Glaucoma is the leading cause of irreversible blindness and is characterized by progressive retinal ganglion cell (RGC) loss and retinal nerve fiber layer thinning. Currently, no existing treatment is effectiv...
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Open AccessAMPK targets PDZD8 to trigger carbon source shift from glucose to glutamine
The shift of carbon utilization from primarily glucose to other nutrients is a fundamental metabolic adaptation to cope with decreased blood glucose levels and the consequent decline in glucose oxidation. AMP-...
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Adenylate kinase phosphate energy shuttle underlies energetic communication in flagellar axonemes
The complexities of energy transfer mechanisms in the flagella of mammalian sperm flagella have been intensively investigated and demonstrate significant diversity across species. Enzymatic shuttles, particula...
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Open AccessAuthor Correction: Identification of an intraocular microbiota
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Open AccessGrowth phase-dependent reorganization of cryptophyte photosystem I antennae
Photosynthetic cryptophytes are eukaryotic algae that utilize membrane-embedded chlorophyll a/c binding proteins (CACs) and lumen-localized phycobiliproteins (PBPs) as their light-harvesting antennae. Cryptoph...
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Investigation of Oil-air Two-Phase Flow Inside Angular Contact Ball Bearing with Textured Cage
Surface texture technology is a method to improve the tribological properties of friction pairs. In this study, a cylindrical texture is designed in cage pocket, and then the volume of fluid model and the mult...
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Open AccessThe emerging role of regulated cell death in ischemia and reperfusion-induced acute kidney injury: current evidence and future perspectives
Renal ischemia‒reperfusion injury (IRI) is one of the main causes of acute kidney injury (AKI), which is a potentially life-threatening condition with a high mortality rate. IRI is a complex process involving ...
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SIRT1 maintains bone homeostasis by regulating osteoblast glycolysis through GOT1
The silent information regulator T1 (SIRT1) is linked to longevity and is a crucial mediator of osteoblast function. We investigated the direct role of Sirt1 during bone modeling and remodeling stages in vivo usi...
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Open AccessInterferon-induced transmembrane protein-1 competitively blocks Ephrin receptor A2-mediated Epstein–Barr virus entry into epithelial cells
Epstein–Barr virus (EBV) can infect both B cells and epithelial cells (ECs), causing diseases such as mononucleosis and cancer. It enters ECs via Ephrin receptor A2 (EphA2). The function of interferon-induced ...
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Genetically optimizing soybean nodulation improves yield and protein content
Symbiotic nitrogen fixation in legume nodules requires substantial energy investment from host plants, and soybean (Glycine max (L.) supernodulation mutants show stunting and yield penalties due to overconsumptio...
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Open AccessCastration alters the ileum microbiota of Holstein bulls and promotes beef flavor compounds
In the beef industry, bull calves are usually castrated to improve flavor and meat quality; however, this can reduce their growth and slaughter performance. The gut microbiota is known to exert a significant i...
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Open AccessPICK1 inhibits the malignancy of nasopharyngeal carcinoma and serves as a novel prognostic marker
Although many important advances have been made in the treatment of nasopharyngeal carcinoma (NPC) in recent years, local recurrence and distant metastasis remain the main factors affecting NPC prognosis. Biom...
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Open AccessEndothelial DR6 in blood-brain barrier malfunction in Alzheimer’s disease
The impairment of the blood-brain barrier (BBB) has been increasingly recognised as a critical element in the early pathogenesis of Alzheimer’s disease (AD), prompting a focus on brain endothelial cells (BECs)...
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Open AccessGut microbial network signatures of early colonizers in preterm neonates with extrauterine growth restriction
Extrauterine growth restriction (EUGR) represents a prevalent condition observed in preterm neonates, which poses potential adverse implications for both neonatal development and long-term health outcomes. The...
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Open AccessRetraction Note: GRP78 determines glioblastoma sensitivity to UBA1 inhibition-induced UPR signaling and cell death
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Open Access40 Hz light flickering promotes sleep through cortical adenosine signaling
Flickering light stimulation has emerged as a promising non-invasive neuromodulation strategy to alleviate neuropsychiatric disorders. However, the lack of a neurochemical underpinning has hampered its therape...
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Open AccessIntegrated analysis of microRNA and messenger RNA expression profiles reveals functional microRNA in infectious bovine rhinotracheitis virus-induced mitochondrial damage in Madin-Darby bovine kidney cells
Studies have confirmed that Infectious bovine rhinotracheitis virus (IBRV) infection induces mitochondrial damage. MicroRNAs (miRNAs) are a class of noncoding RNA molecules, which are involved in various biolo...
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Open AccessProduction and characterization of bacterial cellulose from kombucha-fermented soy whey
Bacterial cellulose (BC) is a high-strong cellulose with high-purity produced by bacteria. The aim of this study was to explore the feasibility of using tofu soy whey as a novel and cheap culture medium to pro...