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Open AccessBile acids induce liver fibrosis through the NLRP3 inflammasome pathway and the mechanism of FXR inhibition of NLRP3 activation
Altered patterns of bile acids (BAs) are frequently present in liver fibrosis, and BAs function as signaling molecules to initiate inflammatory responses. Therefore, this study was conducted to uncover the not...
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Article
Open AccessCastration alters the ileum microbiota of Holstein bulls and promotes beef flavor compounds
In the beef industry, bull calves are usually castrated to improve flavor and meat quality; however, this can reduce their growth and slaughter performance. The gut microbiota is known to exert a significant i...
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Article
A mesh-free finite-difference scheme for frequency-domain acoustic wave simulation with topography
With the increasing complexity of seismic exploration objects, numerical simulation methods that can accurately describe topographical surfaces and complex geological structures are very important. In this stu...
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Article
Design and Assessments of Gradient Chamfer Trigger for Enhancing Energy-Absorption of CFRP Square Tube
It is proposed to use the gradient chamfer trigger method to explore the axial crush response phenomenon of Carbon fiber reinforced plastic (CFRP) composite materials square tube. A reliable non-linear progres...
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Article
Open AccessCorrection: Effects of inoculating feruloyl esterase-producing Lactiplantibacillus plantarum A1 on ensiling characteristics, in vitro ruminal fermentation and microbiota of alfalfa silage
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Open AccessEffects of inoculating feruloyl esterase-producing Lactiplantibacillus plantarum A1 on ensiling characteristics, in vitro ruminal fermentation and microbiota of alfalfa silage
Ferulic acid esterase (FAE)-secreting Lactiplantibacillus plantarum A1 (Lp A1) is a promising silage inoculant due to the FAE’s ability to alter the plant cell wall structure during ensiling, an action that is ex...
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Article
Krankheitslast von Darmkrebs in Deutschland: Epidemiologie und Kosten
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Open AccessReal-world patient characteristics and treatment outcomes among nontransplanted multiple myeloma patients who received Bortezomib in combination with Lenalidomide and Dexamethasone as first line of therapy in the United States
There is limited real-world evidence that describes patients with newly diagnosed multiple myeloma (NDMM) treated with the bortezomib, lenalidomide, and dexamethasone (VRd) triplet regimen. We evaluated patien...
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Article
Open AccessEffects of different protein sources on nutrient disappearance, rumen fermentation parameters and microbiota in dual-flow continuous culture system
Scarce high-quality protein feed resources has limited the development of animal husbandry. In this study, we used a dual-flow continuous culture system to evaluate effects of difference dietary protein source...
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Article
Mechanisms and Stabilization Measures of Layered Slope: A Study Case of a Layered Slope in Sichuan, China
The preferred plane often exists in a layered slope, which has a main influence on the slope stability. Such a plane can evolve into the failure surface, due to the internal and external triggers of landslides...
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Article
Open AccessEffects of brewers’ spent grain protein hydrolysates on gas production, ruminal fermentation characteristics, microbial protein synthesis and microbial community in an artificial rumen fed a high grain diet
Brewers’ spent grain (BSG) typically contains 20% – 29% crude protein (CP) with high concentrations of glutamine, proline and hydrophobic and non-polar amino acid, making it an ideal material for producing val...
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Article
Open AccessFeed nutritional value of brewers’ spent grain residue resulting from protease aided protein removal
This study was conducted to evaluate the feed nutritional value of brewers’ spent grain (BSG) residue resulting from protease aided protein removal. The nutritional value was measured as nutrient content, gas ...
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Article
Gesundheitsökonomie der Krebsfrüherkennung in Deutschland: Welche Interventionen sind kosteneffektiv bei bevölkerungsweiter Umsetzung?
Nur ein geringer Teil der Gesundheitsausgaben in Deutschland wird für Prävention und Früherkennung aufgewendet. Das Rationale von Früherkennungsmaßnahmen ist es, (noch) symptomlose Personen mit dem Vor- oder F...
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Article
Open AccessGastrointestinal Spatiotemporal mRNA Expression of Ghrelin vs Growth Hormone Receptor and New Growth Yield Machine Learning Model Based on Perturbation Theory
The management of ruminant growth yield has economic importance. The current work presents a study of the spatiotemporal dynamic expression of Ghrelin and GHR at mRNA levels throughout the gastrointestinal tract ...
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Article
Recombinant HCMV UL128 expression and functional identification of PBMC-attracting activity in vitro
Human cytomegalovirus (HCMV) has evolved several immune evasion strategies. One strategy is controlling the movement of peripheral blood mononuclear cells (PBMCs) by encoding homologues of chemokines. Our aim ...
