11 Result(s)
within
**aobo Wang
Medicine & Public Health
Imaging / Radiology
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Article
Open AccessKinetic 18F-FDG PET/CT imaging of hepatocellular carcinoma: a dual input four-compartment model
The endoplasmic reticulum plays an important role in glucose metabolism and has not been explored in the kinetic estimation of hepatocellular carcinoma (HCC) via 18F-fluoro-2-deoxy-d-glucose PET/CT.
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Article
Evaluation of novel anti-CEACAM6 antibody-based conjugates for radioimmunotheranostics of pancreatic ductal adenocarcinoma
Pancreatic ductal adenocarcinoma (PDAC) is a highly malignant solid tumor that lacks early diagnostic methods. Recently, targeted immunotherapy and radiotherapy have been integrated with radionuclide-antibody ...
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Article
Open AccessShort-term PET-derived kinetic estimation for the diagnosis of hepatocellular carcinoma: a combination of the maximum-slope method and dual-input three-compartment model
Kinetic estimation provides fitted parameters related to blood flow perfusion and fluorine-18-fluorodeoxyglucose (18F-FDG) transport and intracellular metabolism to characterize hepatocellular carcinoma (HCC) but...
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Article
A novel 18F-labeled agonist for PET imaging of stimulator of interferon gene expression in tumor-bearing mice
Stimulator of interferon genes (STING) protein plays a vital role in the immune surveillance of tumor microenvironment. Monitoring STING expression in tumors benefits the relevant STING therapy. This study aim...
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Article
Preclinical and first-in-human evaluation of 18F-labeled D-peptide antagonist for PD-L1 status imaging with PET
PD-L1 PET imaging allows for the whole body measuring its expression across primary and metastatic tumors and visualizing its spatiotemporal dynamics before, during, and after treatment. In this study, we repo...
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Article
Preclinical and exploratory human studies of novel 68Ga-labeled D-peptide antagonist for PET imaging of TIGIT expression in cancers
While TIGIT has been propelled as a next-generation target in cancer immunotherapy, anti-TIGIT therapy seems to be promising for a fraction of patients in clinical trials. Therefore, patient stratification is ...
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Article
Open AccessDynamic chaotic gravitational search algorithm-based kinetic parameter estimation of hepatocellular carcinoma on 18F-FDG PET/CT
Kinetic parameters estimated with dynamic 18F-FDG PET/CT can help to characterize hepatocellular carcinoma (HCC). We aim to evaluate the feasibility of the gravitational search algorithm (GSA) for kinetic paramet...
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Article
Open AccessApplication value of the treatment of breast cancer bone metastases with radioactive seed 125I implantation under CT-guidance
To investigate the application value of the treatment of breast cancer bone metastases with radioactive seed 125I implantation under CT-guidance.
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Article
Characterizing omental PET/CT findings for differentiating tuberculous peritonitis from peritoneal carcinomatosis
To characterize and investigate PET/CT findings in the omentum in the differentiation of tuberculous peritonitis (TBP) and peritoneal carcinoma (PC).
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Article
Feasibility of perfusion and early-uptake 18F-FDG PET/CT in primary hepatocellular carcinoma: a dual-input dual-compartment uptake model
PET enables a concurrent evaluation of perfusion status and metabolic activity. We aimed to evaluate the feasibility of perfusion and early-uptake 18F-FDG PET/CT in hepatocellular carcinoma (HCC) using a dual-inp...
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Article
Altered brain anatomical networks and disturbed connection density in brain tumor patients revealed by diffusion tensor tractography
Brain tumor patients are usually accompanied by impairments in cognitive functions, and these dysfunctions arise from the altered diffusion tensor of water molecules and disrupted neuronal conduction in white ...
