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Article
Open AccessNT5DC2 promotes tumor cell proliferation by stabilizing EGFR in hepatocellular carcinoma
Most hepatocellular carcinoma (HCC) patients are diagnosed at an advanced stage; however, the effect of systemic therapy on advanced HCC remains undetermined. Therefore, new treatment targets must be identifie...
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Article
Open AccessUSP49 participates in the DNA damage response by forming a positive feedback loop with p53
The p53 tumor suppressor is a critical factor in the DNA damage response (DDR), and regulation of p53 stability has a key role in this process. In our study, we identified USP49 as a novel deubiquitinase (DUB)...
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Article
Open AccessPFKFB3 blockade inhibits hepatocellular carcinoma growth by impairing DNA repair through AKT
Overexpression of 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (PFKFB3), a key molecule of glucose metabolism in cytoplasm, has been found in various tumors. Emerging evidence has suggested that PFKFB...
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Studies on the Psii Particles and Core Complexes Using Femtosecond Absorption Spectroscopy
The primary reaction is one of the key processes in photosynthesis. In photosystem II (PSII), the solar energy is primarily harvesting by LHCII, which binds most of the chlorophylls. Then the energy is transfe...