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Article
Open AccessA novel protein FNDC3B-267aa encoded by circ0003692 inhibits gastric cancer metastasis via promoting proteasomal degradation of c-Myc
Gastric cancer (GC) ranks fifth in global cancer incidence and third in mortality rate among all cancer types. Circular RNAs (circRNAs) have been extensively demonstrated to regulate multiple malignant biologi...
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Article
Inhibition of PPP1R15A alleviates osteoporosis via suppressing RANKL-induced osteoclastogenesis
Osteoporosis results from overactivation of osteoclasts. There are currently few drug options for treatment of this disease. Since the successful development of allosteric inhibitors, phosphatases have become ...
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Article
Open AccessNADPH oxidase 2 mediates cardiac sympathetic denervation and myocyte autophagy, resulting in cardiac atrophy and dysfunction in doxorubicin-induced cardiomyopathy
Doxorubicin has been used extensively as a potent anticancer agent, but its clinical use is limited by its cardiotoxicity. However, the underlying mechanisms remain to be fully elucidated. In this study, we te...
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Article
Design of an active-source seismic detection system based on illumination analysis and migration imaging experiments: considering the Zhuxi mining area as an example
The purpose of this paper is to discuss the feasibility of utilizing the non-explosive source green seismic exploration technology to detect mineral resources in the deep of complex mountainous areas of wester...
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Article
The Community of Arbuscular Mycorrhizal Fungi in Sugarcane Rhizosphere Soils in Guangxi, China
In order to analyze the community of the arbuscular mycorrhizal fungi (AMF) in the rhizosphere soil and roots of sugarcane in Guangxi, China, this study analyzed the 18S rDNA gene sequences, soil physicochemic...
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Article
Open AccessEffect of ultrasound-guided continuous erector spinae plane block on postoperative pain and inflammatory response in patients undergoing modified radical mastectomy for breast cancer: study protocol for a randomised controlled trial
A single injection of local anaesthetic (LA) in the erector spinae plane block (ESPB) can reduce pain after modified radical mastectomy (MRM) surgery, but the duration of analgesia is affected by the duration ...
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Article
Effects of Mixed Crop** on Sugarcane Growth and the Community of Arbuscular Mycorrhizal Fungi
To explore the effects of mixed crop** of different sugarcane varieties on the growth of sugarcane and the community structure of arbuscular mycorrhizal fungi (AMF), field experiments were conducted using RO...
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Article
Open AccessOptimized strategy for schistosomiasis elimination: results from marginal benefit modeling
Poverty contributes to the transmission of schistosomiasis via multiple pathways, with the insufficiency of appropriate interventions being a crucial factor. The aim of this article is to provide more economic...
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Article
Synthesis of hetero-site nucleation twisted bilayer MoS2 by local airflow perturbations and interlayer angle characterization
Twisted bilayer transition metal dichalcogenides including MoS2 have attracted great interest due to their unique Moiré superlattice induced electronic flat bands. High-quality twisted bilayer TMDs with uniform M...
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Article
Open AccesshMSCs treatment attenuates murine herpesvirus-68 (MHV-68) pneumonia through altering innate immune response via ROS/NLRP3 signaling pathway
Immunocompromised individuals are particularly vulnerable to viral infections and reactivation, especially endogenous herpes viruses such as Epstein-Barr virus (EBV), a member of oncogenic gamma-herpesviruses,...
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Article
Schisandrin B Improves the Hypothermic Preservation of Celsior Solution in Human Umbilical Cord Mesenchymal Stem Cells
Human umbilical cord mesenchymal stem cells (hUCMSCs) have emerged as promising therapy for immune and inflammatory diseases. However, how to maintain the activity and unique properties during cold storage and...
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Article
Reliability and construct validity of a simplified Chinese language version of Academic Encouragement Scale for Chinese undergraduates and postgraduates
In this study, the Academic Encouragement Scale (AES) was revised in Chinese. A total of 645 Chinese undergraduates and graduate students participated in the test.The results show that there are 10 items in th...
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Article
Open AccessLessons for the clinical nephrologist: a rare case with MGRS characterized by combined crystalline light chain proximal tubulopathy and crystal-storing histiocytosis responding to daratumumab
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Article
High-throughput data on circular RNA reveal novel insights into chronic glomerulonephritis
Circular RNAs (circRNAs), a unique novel type of RNA, have been widely reported to be involved in physiologic and pathologic processes in humans. However, the exact molecular pathogenesis of circRNAs in chroni...
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Article
Development of 3He-filled linear position-sensitive detector for neutron scattering instruments at CSNS
Helium-3-filled linear position-sensitive detectors (LPSDs) have been widely applied to neutron scattering instruments in recent decades owing to the high detection efficiency, the excellent neutron/gamma disc...
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Article
A fluorescent probe based on a phenylalanine derivative is capable of sequential detection of Zn2+ and Cys/His
A facile and dual fluorescent chemosensor (named 7-IDF) based on a phenylalanine derivative with an indole group was designed and synthesized. 7-IDF can selectively and sensitively detect Zn2+ via obvious fluores...
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Article
Large area 3He tube array detector with modular design for multi-physics instrument at CSNS
The multi-physics instrument (MPI) is the first user cooperative instrument at the China Spallation Neutron Source (CSNS). It was designed to explore the structures of complex materials at multiple scales base...
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Reference Work Entry In depth
International Consensus on Natural Orifice Specimen Extraction Surgery (NOSES) for Gastric Cancer (2019)
At present, natural orifice specimen extraction surgery (NOSES) has attracted more and more attention worldwide, because of its great advantages including minimal cutaneous trauma and postoperative pain, fast ...
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Article
Open AccessComparative genome anatomy reveals evolutionary insights into a unique amphitriploid fish
Triploids are rare in nature because of difficulties in meiotic and gametogenic processes, especially in vertebrates. The Carassius complex of cyprinid teleosts contains sexual tetraploid crucian carp/goldfish (C...
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Article
Open AccessShort term outcomes of extremely low birth weight infants from a multicenter cohort study in Guangdong of China
With the increase in extremely low birth weight (ELBW) infants, their outcome attracted worldwide attention. However, in China, the related studies are rare. The hospitalized records of ELBW infants discharged...
