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Article
Open AccessOpen-hole extension limit of offshore extended-reach well considering formation collapse
The current extension limit prediction model for offshore extended-reach well (ERW) in mudstone does not consider the formation collapse, which poses a huge risk to offshore drilling construction. To address t...
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Article
Theoretically and Experimentally Exploring the Inhibition Effect of Imidazole Sulfonic Acid Derivatives with Multiple Adsorption Sites in 1.0 mol/L HCl
Corrosion inhibitors have played a huge role in daily life and industrial production. Imidazole and sulfonic acid groups have high corrosion inhibition capabilities. To further improve their excellent corrosio...
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Article
Open AccessMOC1 cleaves Holliday junctions through a cooperative nick and counter-nick mechanism mediated by metal ions
Holliday junction resolution is a crucial process in homologous recombination and DNA double-strand break repair. Complete Holliday junction resolution requires two stepwise incisions across the center of the ...
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Article
Open AccessEffect of swab and surge pressure on the time-dependent wellbore natural fracture development
Drilling engineers continue to grapple with the persistent challenge of maintaining wellbore stability. Throughout the drilling process, the wellbore pressure experiences fluctuations induced by various factor...
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Article
Open AccessAltered chromatin topologies caused by balanced chromosomal translocation lead to central iris hypoplasia
Despite the advent of genomic sequencing, molecular diagnosis remains unsolved in approximately half of patients with Mendelian disorders, largely due to unclarified functions of noncoding regions and the diff...
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Article
Open AccessInfluence of eye-related behavior on myopia among junior middle school students under the background of double reduction during the COVID-19 pandemic
To investigate the changes in the unhealthy eye-related behaviors of junior middle school students during the COVID-19 pandemic and the double reduction policy and its relationship with myopia.
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Article
Open AccessReduction in Serum Concentrations of Uremic Toxins Driven by Bifidobacterium Longum Subsp. Longum BL21 is Associated with Gut Microbiota Changes in a Rat Model of Chronic Kidney Disease
Gut microbiota dysbiosis and consequent impairment of gut barrier function, culminating in elevated levels of uremic toxins, are prevalent in chronic kidney disease (CKD) patients. These toxins, notably indoxy...
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Article
Open AccessAssociations between perceived and actual risk of HIV infection and HIV prevention services uptake among men who have sex with men in Shandong province, China: a cross-sectional study
Associations between perceived and actual risk of HIV infection and HIV prevention services uptake are inconclusive. This study aimed to evaluate the discrepancy between the perceived and actual HIV risk, and ...
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Article
Open AccessUtilization of diverse oligosaccharides for growth by Bifidobacterium and Lactobacillus species and their in vitro co-cultivation characteristics
Various approaches have been used to study the relationship between prebiotics and probiotics. The utilization of different carbohydrates by probiotics depends on the biochemical properties of the enzymes and ...
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Article
FOXP3 expression in esophageal squamous cell carcinoma
Investigating the impact of FOXP3 (transcription factor forkhead box P3) expression on the biological behavior of esophageal squamous cell carcinoma (ESCC) and its influence on the sensitivity of ESCC cells to...
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Article
Electric Potential Response Characteristics of Coal Under Stress Wave Loading
Monitoring the electric potential (EP) response induced by coal deformation and rupture is essential to the safety of underground engineering under extreme load and stress wave disturbance conditions. In this ...
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Article
Auricular Acupressure in Relieving PONV and Promoting Gastrointestinal Function Recovery in Females After Laparoscopic Sleeve Gastrectomy: A Prospective Randomized Controlled Trial
The role of current pharmacological treatment after laparoscopic sleeve gastrectomy (LSG) is limited. The incidence of postoperative nausea and vomiting (PONV) after LSG remains high. Auricular acupressure (AA...
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Article
Open AccessLongitudinal viral shedding and antibody response characteristics of men with acute infection of monkeypox virus: a prospective cohort study
Understanding of infection dynamics is important for public health measures against monkeypox virus (MPXV) infection. Herein, samples from multiple body sites and environmental fomites of 77 acute MPXV infecti...
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Article
Open AccessSequential inertial linear ADMM algorithm for nonconvex and nonsmooth multiblock problems with nonseparable structure
The alternating direction method of multipliers (ADMM) has been widely used to solve linear constrained problems in signal processing, matrix decomposition, machine learning, and many other fields. This paper ...
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Article
SIT1 identifies circulating hypoactive T cells with elevated cytotoxic molecule secretion in systemic lupus erythematosus patients
This study aims to elucidate the expression and functionality of SIT1 in circulating CD8/CD4 + T cells in humans and to delineate its significance in systemic lupus erythematosus (SLE) patients. We employed mu...
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Article
Clinical Analysis of Risk Factors and Perinatal Outcomes in Recurrent Pre-Eclampsia with Severe Features
To analyze the differences in risk factors and pregnancy outcomes between recurrent and initial pre-eclampsia(PE) with severe features. Data from recurrent (n = 128) and initial (n = 904) PE with severe features ...
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Article
Study on creep properties of weak layer rock of slope under damage coupling
Based on the fractional order calculus theory and Weibull distribution, the fractional order nonlinear creep constitutive equation of green mudstone in the weak interlayer of slope under the combined action of...
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Article
Influence of 3D Aggregate Shape on the Meso-Structure of 2D Cross-Sectional Concrete by the Numerical Slicing Method
Aggregate shape is essential for evaluating concrete properties. Most of the existing literature utilizes X-ray computed tomography (X-CT) to assess the morphological characteristics of 2D/3D aggregates. Howev...
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Article
Soil microbial richness and community composition are primarily mediated by functional trait diversity of fine roots in subtropical forests
Although plant–microbial interactions are essential to sustain terrestrial ecosystem functions, root–microbial interactions remain poorly understood. Therefore, understanding how functional trait diversity of ...
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Article
Temporal Characteristics of Penetration and Aspiration in Patients with Severe Dysphagia Associated with Lateral Medullary Syndrome
To assess the severity and timing of penetration and aspiration (PA) of severe dysphagia after lateral medullary syndrome (LMS) and its association with temporal characteristics. We performed videofluoroscopic...
