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Article
Open AccessCargo-eliminated osteosarcoma-derived small extracellular vesicles mediating competitive cellular uptake for inhibiting pulmonary metastasis of osteosarcoma
Osteosarcoma (OS) derived small extracellular vesicles (OS-sEVs) have been shown to induce the formation of cancer-associated fibroblasts (CAFs), characterized by elevated pro-inflammatory factor expression an...
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Article
Open AccessA Decade of Churn Prediction Techniques in the TelCo Domain: A Survey
This work surveys the research contributions of the last decade to the prediction of customer churn and adds a perspective toward what is yet to be reached. The main objective of this article is to report on (...
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Article
Perseus: a simple and optimal high-order method for variational inequalities
This paper settles an open and challenging question pertaining to the design of simple and optimal high-order methods for solving smooth and monotone variational inequalities (VIs). A VI involves finding ...
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Article
The Mechanisms of Adipose Stem Cell-Derived Exosomes Promote Wound Healing and Regeneration
Chronic wound healing is a class of diseases influenced by multiple complex factors, causing severe psychological and physiological impact on patients. It is an intractable clinical challenge and its possible ...
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Article
Survey of perspectives on parental leave policies in Canadian surgical training programs
For decades, there have been calls to implement parental leave policies for physicians. However, few studies have examined parental leave in surgical specialties, especially non-childbearing leave. This study ...
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Article
Open AccessGenomics and tumor microenvironment of breast mucoepidermoid carcinoma based on whole-exome and RNA sequencing
Mammary mucoepidermoid carcinoma (MEC) is a rare entity. The molecular characteristics of breast MEC have not been fully investigated due to its rarity. We performed a retrospective study among 1000 patients w...
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Chapter and Conference Paper
Heterogeneous Transfer Learning from a Partial Information Decomposition Perspective
Transfer Learning (TL) encompasses a number of Machine Learning Techniques that take a pre-trained model aimed at solving a task in a Source Domain and try to reuse it to improve the performance of a related t...
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Article
Open AccessIs Lymphadenectomy Reasonable for Elderly Intrahepatic Cholangiocarcinoma Patients?
In this study, we aimed to determine the impact of lymphadenectomy (LND) on clinical outcomes in ICC patients aged ≥ 70 years.
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Article
Decoupling for a greener future: a spatio-temporal analysis of CO2 emissions and economic growth
Climate change mitigation is a pressing global challenge that requires reducing CO2 emissions without hindering economic growth. Using an extended Kaya identity, Logarithmic Mean Divisia Index (LMDI), and Tapio d...
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Article
Open AccessInfluences on treatment-seeking and antibiotic use for common illnesses in eastern China
Antibiotic resistance rates remain high in China where antibiotics are widely used for common illnesses. This study aimed to investigate the influences on people’s decisions on treatment and antibiotic use for...
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Article
Open AccessReconstruction of the temporomandibular joint using a vascularized medial femoral condyle osteocartilaginous flap: an experimental investigation in miniature pigs
Reconstruction of the temporomandibular joint (TMJ) is a significant challenge in maxillofacial surgery. A vascularized medial femoral condyle (MFC) osteocartilaginous flap is a good choice for TMJ reconstruct...
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Article
The influence of S-doped technique on supercapacitor performances for Co(OH)2@nitrogen-doped carbon dots
Recently, Co-based materials have been widely used as a type of supercapacitor. However, Co-based materials are highly restricted due to their low conductivity, poor cyclic performance, and large structural ch...
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Article
Open AccessThe effect of intravenous granisetron on prophylactic ephedrine for preventing hypotension after general anaesthesia induction in elderly patients: a randomized controlled trial
Serotonin 3 receptor antagonists, a commonly used drug for preventing postoperative nausea and vomiting, have recently been reported to decrease the incidence of hypotension and the need for vasoactive drugs a...
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Article
Open AccessOrganic electrochemical transistors as on-site signal amplifiers for electrochemical aptamer-based sensing
Electrochemical aptamer-based sensors are typically deployed as individual, passive, surface-functionalized electrodes, but they exhibit limited sensitivity especially when the area of the electrode is reduced...
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Article
Pathway for the low-carbon consumption pattern transition of residents in six eastern coastal provinces of China: using fuzzy-set qualitative comparative analysis with panel data
China has embarked on society-wide emission reduction initiatives to tackle the growing decarbonization pressures on national economic and social development. The low-carbon consumption pattern transition of t...
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Article
The Role of Housing Mortgage Leverage in Stock Asset Pricing: Evidence from the Chinese A-share Market
This study detects the linkage between housing mortgage leverage and stock asset pricing in China’s A-share stock market. We deduce relevant asset pricing models in which a significant pricing factor—termed th...
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Article
Open AccessAerobic glycolysis enhances HBx-initiated hepatocellular carcinogenesis via NF-κBp65/HK2 signalling
Aerobic glycolysis has been recognized as one of the growth-promoting metabolic alterations of cancer cells. Emerging evidence indicates that nuclear factor κB (NF-κB) plays significant roles in metabolic adap...
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Article
A 10-miRNA risk score-based prediction model for pathological complete response to neoadjuvant chemotherapy in hormone receptor-positive breast cancer
Patients with hormone receptor (HR)-positive tumors breast cancer usually experience a relatively low pathological complete response (pCR) to neoadjuvant chemotherapy (NAC). Here, we derived a 10-microRNA risk...
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Article
Open AccessA control-theoretic perspective on optimal high-order optimization
We provide a control-theoretic perspective on optimal tensor algorithms for minimizing a convex function in a finite-dimensional Euclidean space. Given a function
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Article
A Novel Preparation Method for Effervescent Tablets of **anganfang Containing Fresh Juice using a Semi-Solid Extrusion 3D Printer with Three Cartridge Holders
This study aimed to prepare effervescent tablets of traditional Chinese medicine **anganfang with fresh juice using a semi-solid 3D printer with three cartridge holders to seperate acid and alkali source by dr...