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  1. No Access

    Article

    Naloxone Facilitates Contextual Learning and Memory in a Receptor-Independent and Tet1-Dependent Manner

    Opioids, like morphine and naloxone, regulate the proliferation and neuronal differentiation of neural stem cells (NSCs) in a receptor-independent and ten-eleven translocation methylcytosine dioxygenase (TET1)...

    Fei Meng, Yuan Li, Hao Sun, Changpeng Li, Qian Li… in Cellular and Molecular Neurobiology (2021)

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    Article

    Oxycodone in the Opioid Epidemic: High ‘Liking’, ‘Wanting’, and Abuse Liability

    It is estimated that nearly a third of people who abuse drugs started with prescription opioid medicines. Approximately, 11.5 million Americans used prescription drugs recreationally in 2016, and in 2018, 46,8...

    Cherkaouia Kibaly, Jacob A. Alderete, Steven H. Liu… in Cellular and Molecular Neurobiology (2021)

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    Article

    MicroRNAs in Opioid Pharmacology

    MicroRNAs (miRNA), a class of ~22-nucleotide RNA molecules, are important gene regulators that bind to the target sites of mRNAs to inhibit the gene expressions either through translational inhibition or mRNA ...

    Cheol Kyu Hwang, Yadav Wagley, **-Yee Law… in Journal of Neuroimmune Pharmacology (2012)

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    Article

    Neurite Outgrowth is Dependent on the Association of c-Src and Lipid Rafts

    Regulation of neurite outgrowth is an important aspect not only for proper development of the nervous system but also for tissue regeneration after nerve injury and the treatment of neuropathological condition...

    Hui Zhao, **aoding Cao, Gencheng Wu, Horace H. Loh, **-Yee Law in Neurochemical Research (2009)

  5. No Access

    Article

    Nuclear Factor κB Signaling in Opioid Functions and Receptor Gene Expression

    Opiates are the most powerful of all known analgesics. The prototype opiate morphine has been used as a painkiller for several thousand years. Chronic usage of opiates not only causes drug tolerance, dependenc...

    Yulong L. Chen, **-Yee Law, Horace H. Loh in Journal of Neuroimmune Pharmacology (2006)