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  1. No Access

    Article

    Oxycodone in the Opioid Epidemic: High ‘Liking’, ‘Wanting’, and Abuse Liability

    It is estimated that nearly a third of people who abuse drugs started with prescription opioid medicines. Approximately, 11.5 million Americans used prescription drugs recreationally in 2016, and in 2018, 46,8...

    Cherkaouia Kibaly, Jacob A. Alderete, Steven H. Liu… in Cellular and Molecular Neurobiology (2021)

  2. No Access

    Article

    Non-nociceptive roles of opioids in the CNS: opioids’ effects on neurogenesis, learning, memory and affect

    Mortality due to opioid use has grown to the point where, for the first time in history, opioid-related deaths exceed those caused by car accidents in many states in the United States. Changes in the prescribi...

    Cherkaouia Kibaly, Chi Xu, Catherine M. Cahill… in Nature Reviews Neuroscience (2019)

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    Article

    Neurogenic pain and steroid synthesis in the spinal cord

    The spinal cord (SC) is a biosynthetic center for neurosteroids, including pregnenolone (PREG), progesterone (PROG), and 3α/5α-tetrahydroprogesterone (3α/5α-THP). In particular, anactive form of cytochrome P45...

    Christine Patte-Mensah, Cherkaouia Kibaly… in Journal of Molecular Neuroscience (2006)