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178 Result(s)
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Article
Open AccessMulti-omic characterization of allele-specific regulatory variation in hybrid pigs
Hybrid map** is a powerful approach to efficiently identify and characterize genes regulated through mechanisms in cis. In this study, using reciprocal crosses of the phenotypically divergent Duroc and Lulai...
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Open AccessStructure of cryptophyte photosystem II–light-harvesting antennae supercomplex
Cryptophytes are ancestral photosynthetic organisms evolved from red algae through secondary endosymbiosis. They have developed alloxanthin-chlorophyll a/c2-binding proteins (ACPs) as light-harvesting complexes (...
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Open AccessHarbinger transposon insertion in ethylene signaling gene leads to emergence of new sexual forms in cucurbits
In flowering plants, the predominant sexual morph is hermaphroditism, and the emergence of unisexuality is poorly understood. Using Cucumis melo (melon) as a model system, we explore the mechanisms driving sexual...
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Open AccessCircumventing bottlenecks in H2O2 photosynthesis over carbon nitride with iodine redox chemistry and electric field effects
Artificial photosynthesis using carbon nitride (g-C3N4) holds a great promise for sustainable and cost-effective H2O2 production, but the high carrier recombination rate impedes its efficiency. To tackle this cha...
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A genome-wide association study identifies 25(OH)D3-associated genetic variants in the prediabetic Chinese population
Diabetes mellitus has been a significant public health problem, associated with high rates of morbidity, disability, and mortality. Prediabetes is a crucial period for preventing and managing diabetes. 25(OH)D...
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Open AccessAdherence to the dietary approaches to stop hypertension diet reduces the risk of diabetes mellitus: a systematic review and dose-response meta-analysis
Despite several epidemiological studies reporting a significant association between adherence to the Dietary Approaches to Stop Hypertension (DASH) diet and the risk of diabetes mellitus, the results remain co...
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Open AccessABA-mediated regulation of rice grain quality and seed dormancy via the NF-YB1-SLRL2-bHLH144 Module
Abscisic acid (ABA) plays a crucial role in promoting plant stress resistance and seed dormancy. However, how ABA regulates rice quality remains unclear. This study identifies a key transcription factor SLR1-l...
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Article
Open AccessAn inorganic-blended p-type semiconductor with robust electrical and mechanical properties
Inorganic semiconductors typically have limited p-type behavior due to the scarcity of holes and the localized valence band maximum, hindering the progress of complementary devices and circuits. In this work, ...
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Open AccessZero-shot learning enables instant denoising and super-resolution in optical fluorescence microscopy
Computational super-resolution methods, including conventional analytical algorithms and deep learning models, have substantially improved optical microscopy. Among them, supervised deep neural networks have d...
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Open AccessRevealing the pharmacological mechanisms of nao-an drop** pill in preventing and treating ischemic stroke via the PI3K/Akt/eNOS and Nrf2/HO-1 pathways
Nao-an Drop** Pill (NADP) is a Chinese patent medicine which commonly used in clinic for ischemic stroke (IS). However, the material basis and mechanism of its prevention or treatment of IS are unclear, then...
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Open AccessAn improved technology for monitoring groundwater flow velocity and direction in fractured rock system based on colloidal particles motion
The colloidal borescope, using colloidal particle motion, is used to monitor the flow velocities and directions of groundwater. It integrates advanced techniques such as microscopy, high-speed photography, and...
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Soil Geobacteraceae are the key predictors of neurotoxic methylmercury bioaccumulation in rice
Contamination of rice by the potent neurotoxin methylmercury (MeHg) originates from microbe-mediated Hg methylation in soils. However, the high diversity of Hg methylating microorganisms in soils hinders the p...
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Open AccessIncidence and risk factors for pulmonary hemorrhage after percutaneous CT-guided pulmonary nodule biopsy: an observational study
To evaluate the current incidence of pulmonary hemorrhage and the potential factors contributing to its increased risk after percutaneous CT-guided pulmonary nodule biopsy and to summarize the technical recomm...
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Open AccessLarge exchange-driven intrinsic circular dichroism of a chiral 2D hybrid perovskite
In two-dimensional chiral metal-halide perovskites, chiral organic spacers endow structural and optical chirality to the metal-halide sublattice, enabling exquisite control of light, charge, and electron spin....
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Open AccessTumor-infiltrating immune cells and survival in head and neck squamous cell carcinoma: a retrospective computational study
The immune infiltration profiles of the tumor microenvironment have effects on the prognosis of head and neck squamous cell carcinoma (HNSCC). Whereas, HNSCC is a heterogeneous group of tumors, but past work h...
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Open AccessInvestigations on the effect of natural veined calcite on the mechanical properties of limestone
The damage behavior of limestone rock masses containing calcite mineral filling under uniaxial compression experimental conditions is unclear, and the fracture mechanism of the rock masses needs to be further ...
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Open AccessAuthor Correction: Catalytic enantioselective reductive alkynylation of amides enables one-pot syntheses of pyrrolidine, piperidine and indolizidine alkaloids
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Open AccessMeasuring entanglement entropy and its topological signature for phononic systems
Entanglement entropy is a fundamental concept with rising importance in various fields ranging from quantum information science, black holes to materials science. In complex materials and systems, entanglement...
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Open AccessImproving polygenic risk prediction in admixed populations by explicitly modeling ancestral-differential effects via GAUDI
Polygenic risk scores (PRS) have shown successes in clinics, but most PRS methods focus only on participants with distinct primary continental ancestry without accommodating recently-admixed individuals with m...
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Open AccessToripalimab plus capecitabine in the treatment of patients with residual nasopharyngeal carcinoma: a single-arm phase 2 trial
Patients with residual nasopharyngeal carcinoma after receiving definitive treatment have poor prognoses. Although immune checkpoint therapies have achieved breakthroughs for treating recurrent and metastatic ...