-
Article
Open AccessMucosal TLR5 activation controls healthspan and longevity
Addressing age-related immunological defects through therapeutic interventions is essential for healthy aging, as the immune system plays a crucial role in controlling infections, malignancies, and in supporti...
-
Article
Analysis of random mutations in Salmonella Gallinarum dihydropteroate synthase conferring sulfonamide resistance
In bacteria and primitive eukaryotes, sulfonamide antibiotics block the folate pathway by inhibiting dihydropteroate synthase (FolP) that combines para-aminobenzoic acid (pABA) and dihydropterin pyrophosphate ...
-
Article
Open AccessAnalysis of antibiotic resistance gene cassettes in a newly identified Salmonella enterica serovar Gallinarum strain in Korea
Antimicrobial resistant pathogens are a global health threat driven by the indiscriminate use of antimicrobials. Antimicrobial resistance can be acquired by resistance genes encoded by mobile genetic elements....
-
Article
Open AccessAdditive effects of narrowband light and optical defocus on chick eye growth and refraction
In the past decade and during the COVID pandemic, the prevalence of myopia has reached epidemic proportions. To address this issue and reduce the prevalence of myopia and its complications, it is necessary to ...
-
Article
Open AccessLaboratory markers of severity across three COVID-19 outbreaks in Australia: has Omicron and vaccinations changed disease presentation?
COVID-19 has rapidly evolved since it was first discovered in December 2019. We aimed to retrospectively review our experience with COVID-19 infection across 2020–2022, focusing on differences in laboratory ma...
-
Article
Open AccessThe repertoire of testicular extracellular vesicle cargoes and their involvement in inter-compartmental communication associated with spermatogenesis
Spermatogenesis is regulated by a complex network of intercellular communication processes. Extracellular vesicles (EVs) are one of the important mediators in intercellular communication. Previous reports have...
-
Article
Open AccessMonolayer Graphitic Carbon Nitride as Metal-Free Catalyst with Enhanced Performance in Photo- and Electro-Catalysis
The g-C3N4 monolayer in the perfect 2D limit was successfully realized, for the first time, by the well-defined chemical strategy based on the bottom...
-
Article
NICLOSAMIDE-EXFOLIATED ANIONIC CLAY NANOHYBRID REPURPOSED AS AN ANTIVIRAL DRUG FOR TACKLING COVID-19; ORAL FORMULATION WITH TWEEN 60/EUDRAGIT S100
The ongoing pandemic, COVID-19 (SARS-CoV-2), has afflicted millions of people around the world, necessitating that the scientific community work, diligently and promptly, on suitable medicaments. Although vacc...
-
Article
Chitosan hybrids for cosmeceutical applications in skin, hair and dental care: an update
Cosmeceuticals are materials which can have benefits of cosmetics as well as pharmaceutics. Even though there are different kinds of materials used, biopolymer based are the most relevant one, owing to their e...
-
Article
Open AccessIntrastriatal administration of coenzyme Q10 enhances neuroprotection in a Parkinson’s disease rat model
Parkinson’s disease is a neurodegenerative disorder, and no treatment has been yet established to prevent disease progression. Coenzyme Q10, an antioxidant, has been considered a promising neuroprotective agen...
-
Article
Open AccessSustainable and recyclable super engineering thermoplastic from biorenewable monomer
Environmental and health concerns force the search for sustainable super engineering plastics (SEPs) that utilise bio-derived cyclic monomers, e.g. isosorbide instead of restricted petrochemicals. However, pre...
-
Article
Vectorized Clay Nanoparticles in Therapy and Diagnosis
Over the past several decades, clay minerals have been applied in various bio-fields such as drug and drug additives, animal medicine and feed additives, cosmetics, biosensors, etc. Among various research area...
-
Article
Open AccessGABAergic signaling linked to autophagy enhances host protection against intracellular bacterial infections
Gamma-aminobutyric acid (GABA) is the principal inhibitory neurotransmitter in the brain; however, the roles of GABA in antimicrobial host defenses are largely unknown. Here we demonstrate that GABAergic activ...
-
Article
Clay-organic intumescent hybrid system for the synergetic flammability of polymer nanocomposites
A polyethylene vinyl acetic acid (EVA) nanocomposite comprising of an intumescent agent that incorporates ammonium phosphate monobasic, mono-pentaerythritol, and melamine with a cationic nanoclay was set up th...
-
Article
Open AccessThe hepcidin-ferroportin axis controls the iron content of Salmonella-containing vacuoles in macrophages
Macrophages release iron into the bloodstream via a membrane-bound iron export protein, ferroportin (FPN). The hepatic iron-regulatory hormone hepcidin controls FPN internalization and degradation in response ...
-
Article
Open AccessMindfulness-Based Stress Reduction (MBSR) or Psychoeducation for the Reduction of Menopausal Symptoms: A Randomized, Controlled Clinical Trial
Psychological and behavioural interventions may be effective in reducing menopause-related symptoms. This randomized controlled trial aimed to evaluate the effectiveness of Mindfulness-based Stress Reduction (...
-
Article
Predation risk and breeding site value determine male behavior and indirectly affect survivorship of their offspring
Predation is one of the main drivers of behavioral adaptation in prey. In species with parental care, predation can affect survival of both adults and the offspring under their care. This effect can be further...
-
Article
Pattern-coated titanium bone fixation plate for dual delivery of vancomycin and alendronate
Metallic bone-fixation devices have been widely used in the treatment of fractured bones. However, there are still some unmet clinical needs associated with post-surgical infection and hampered bone repair. Th...
-
Article
Open AccessAbstracts from the 8th International Congress of the Asia Pacific Society of Infection Control (APSIC)
-
Article
Open AccessMicrovasculature remodeling in the mouse lower gut during inflammaging
Inflammaging is defined as low-grade, chronic, systemic inflammation in aging, in the absence of overt infection. Age-associated deterioration of gastrointestinal function could be ascribed to the inflammaging...
