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Article
The interaction of Yougui pill and its disassembled prescriptions with liposome mimetic biomembrane
Yougui pill is one of the representative prescriptions of "reinforcing Yang from Yin" theory (a basic theory of traditional Chinese medicine). Differential scanning calorimetry (DSC), isothermal titration calorim...
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Article
Development and validation of a simultaneous method for the analysis of benzothiazoles and organic ultraviolet filters in various environmental matrices by GC–MS/MS
The presence of benzothiazoles (BTHs) and organic ultraviolet filters (UV filters) in aquatic ecosystems has emerged as a significant environmental issue, requiring urgent and efficient determination methods. ...
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Article
Quantitative and real-time measurement of helicase-mediated intra-stranded G4 unfolding in bulk fluorescence stopped-flow assays
G-Quadruplexes (G4s) are thermodynamically stable, compact, and poorly hydrated structures that pose a potent obstacle for chromosome replication and gene expression, and requiring resolution by helicases in a...
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Article
Elevated circulating asymmetric dimethylarginine levels in rheumatoid arthritis: a systematic review and meta-analysis
Rheumatoid arthritis (RA) patients have increased risk of cardiovascular disease (CVD) death. Elevated asymmetric dimethylarginine (ADMA) levels have been reported to be an independent predictor of CVD morbidi...
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Article
The interaction of paeonol with DPPC liposomes
Differential scanning calorimetry and synchrotron X-ray diffraction techniques have been employed to investigate the interaction of paeonol with DPPC liposomes and to investigate the location of paeonol molecu...
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Article
Diacetyl content reduction in industrial brewer’s yeast through ILV2 disruption and BDH1 expression
Diacetyl is crucial to beer maturation because of its characteristic buttery taste. New industrial brewer’s yeast strains, including single ILV2 allele disruption (QI2), single ILV2 allele disruption and BDH1 ove...
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Article
Identification of antioxidant peptides from protein hydrolysates of scallop (Patinopecten yessoensis) female gonads
Scallop (Patinopecten yessoensis) female gonad hydrolysates (SFGHs) were obtained by using neutrase. The resulting hydrolysates possessed DPPH radical scavenging activity, ferrous ion-chelating ability, and reduc...
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Article
Application of the novel bioluminescent ligand–receptor binding assay to relaxin-RXFP1 system for interaction studies
Relaxin is a prototype of the relaxin family peptide hormones and plays important biological functions by binding and activating the G protein-coupled receptor RXFP1. To study their interactions, in the presen...
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Article
Secretory overexpression and isotopic labeling of the chimeric relaxin family peptide R3/I5 in Pichia pastoris
Relaxin family peptides are a group of peptide hormones with divergent biological functions. Mature relaxin family peptides are typically composed of two polypeptide chains with three disulfide linkages, rende...
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Article
Simultaneous determination of sulfonamides and metabolites in manure samples by one-step ultrasound/microwave-assisted solid–liquid–solid dispersive extraction and liquid chromatography–mass spectrometry
An in-line matrix cleanup method was used for the simultaneous extraction of 15 sulfonamides and two metabolites from manure samples. The ultrasound/microwave-assisted extraction (UMAE) combined with solid–liq...
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Article
Determination of 13 Phenolic Compounds in Rice Wine by High-Performance Liquid Chromatography
Rice wines are widely consumed by the general public in Asian countries, while comprehensive studies focused on the individual phenolic compounds in rice wines are limited. A rapid method for simultaneous dete...
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Article
Simultaneous Determination of Flumequine and Oxolinic Acid Residues in Aquatic Products Using Pressurized Capillary Electrochromatography
A rapid method for detection of flumequine (FQ) and oxolinic acid (OA) residues from fish tissues was established using pressurized capillary electrochromatography (pCEC). Residual FQ and OA were extracted fro...
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Article
Influence of electronic effect on methane catalytic combustion over PdNi/Al2O3
A series of PdNi/Al2O3 catalysts with different compositions was prepared by co-reduction method. The influence of Ni amount on the catalytic combustion of methane was studied. X-ray diffractometry and X-ray phot...
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Article
Arginine aminopeptidase from white shrimp (Litopenaeus vannamei) muscle: purification and characterization
Aminopeptidases act on N-terminal of proteins and peptides produce free amino acids making an impact on the final flavor of foods. An arginine aminopeptidase (RAP) which preferred to hydrolyze basic amino acid...
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Article
Anti-diabetic effects of polysaccharides from ethanol-insoluble residue of Schisandra chinensis (Turcz.) Baill on alloxan-induced diabetic mice
The ethanol-insoluble residue of Schisandra generated during lignans industrial production is usually treated as solid waste. However, there is active polysaccharide which could be used in it. In this work, the w...
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Article
Improvement of enzymatic stability and intestinal permeability of deuterohemin-peptide conjugates by specific multi-site N-methylation
The deuterohemin-peptide conjugate, DhHP-6 (Dh-β-AHTVEK-NH2), is a microperoxidase mimetic, which has demonstrated substantial benefits in vivo as a scavenger of reactive oxygen species (ROS). In this study, spec...
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Article
A DSC study of paeonol-encapsulated liposomes, comparison the effect of cholesterol and stigmasterol on the thermotropic phase behavior of liposomes
Thermotropic phase behaviors of paeonol-encapsulated liposomes containing stigmasterol or cholesterol have been investigated by differential scanning calorimetry. We compared the thermotropic phase behavior of...
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Article
LC–MS–MS Quantitative Determination of Brivudine in Human Plasma and Its Application to Pharmacokinetic Studies
A sensitive and specific liquid chromatography–electrospray ionization–tandem mass spectrometry method has been developed and validated for the identification and quantification of brivudine in human plasma us...
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Article
Determination of 5-n-Butyl-4-{4-[2-(1H-tetrazole-5-yl)-1H-pyrrol-1-yl]phenylmethyl}-2,4-dihydro-2-(2,6-dichloridephenyl)-3H-1,2,4-triazol-3-one, a New Angiotensin Type 1 Receptor Antagonist in Rat Plasma by LC-ESI-MS: Application to Pharmacokinetic Studies
A simple and sensitive reversed-phase LC-ESI-MS method to identify and quantitate 5-n-butyl-4-{4-[2-(1H-tetrazole-5-yl)-1H-pyrrol-1-yl]phenylmethyl}-2,4-dihydro-2-(2,6-dichloridephenyl)-3H-1,2,4-triazol-3-one (1b...
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Article
Liposome-based flow injection enzyme immunoassay for theophylline
Preliminary results are presented on the development of a sensitive, quantitative immunoassay based on a regenerable, flow injection analysis system incorporating a double-amplification approach. The double am...