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  1. No Access

    Article

    A fast DBSCAN algorithm using a bi-directional HNSW index structure for big data

    The Density Based Spatial Clustering of Applications with Noise (DBSCAN) algorithm is one of the most popular and effective density-based clustering algorithms at present. Although it can effectively identify ...

    Shaoyuan Weng, Zongwen Fan, ** Gou in International Journal of Machine Learning … (2024)

  2. Article

    Open Access

    Antiviral activity of luteolin against porcine epidemic diarrhea virus in silico and in vitro

    Porcine epidemic diarrhea virus (PEDV) mainly causes acute and severe porcine epidemic diarrhea (PED), and is highly fatal in neonatal piglets. No reliable therapeutics against the infection exist, which poses...

    Jieru Wang, **aoyu Zeng, Jiaojiao Gou, **aojie Zhu, Dongdong Yin in BMC Veterinary Research (2024)

  3. No Access

    Article

    Gapr for large-scale collaborative single-neuron reconstruction

    Whole-brain analysis of single-neuron morphology is crucial for unraveling the complex structure of the brain. However, large-scale neuron reconstruction from terabyte and even petabyte data of mammalian brain...

    Lingfeng Gou, Yanzhi Wang, Le Gao, Yiting Zhong, Lucheng **e in Nature Methods (2024)

  4. Article

    Open Access

    Relationship between plasma TNF-α levels and agitation symptoms in first episode patients with schizophrenia

    Increasing evidence suggested that immune abnormalities involved in the pathophysiology of schizophrenia. However, the relationship between immunity and clinical features has not been clarified. The aim of thi...

    **aoying Wang, Wen** Chen, Mengzhuang Gou, Wei Li, Na Li, **ghui Tong in BMC Psychiatry (2024)

  5. No Access

    Article

    A Semi-Supervised Model for Fine-Grained Identification of Oil Emulsions on the Sea Surface Using Hyperspectral Imaging

    After oil spills occur in the ocean, oil pollutants usually appear in the form of oil emulsions under the influence of hydrodynamics. Hyperspectral remote sensing technology, which provides abundant spectral i...

    Ming **e, Tao Gou, Shuang Dong, Ying Li in Journal of the Indian Society of Remote Sensing (2024)

  6. No Access

    Article

    Solid solution strategy modulated defects engineering of (Cr1-xVx)2AlC MAX phase toward superior electromagnetic wave absorption

    Defects engineering is an effective strategy for manipulating electromagnetic parameters and enhancing electromagnetic wave (EMW) absorption capacity. However, the relationship between them is not clear, espec...

    Ji-Lin Gou, Yu-Kai Chang, Shu Liu, Peng-Hui Li, **-Hao Cui, Qian-Ku Hu in Rare Metals (2024)

  7. No Access

    Article

    Representation separation adversarial networks for cross-modal retrieval

    Cross-modal retrieval aims to search the semantically similar instances from the other modalities by giving a query from one modality. Recently, generative adversarial networks (GANs) has been proposed to mode...

    Jiaxin Deng, Weihua Ou, Jian** Gou, He** Song, Anzhi Wang, **ng Xu in Wireless Networks (2024)

  8. No Access

    Article

    Dynamic regulation of stem cell adhesion and differentiation on degradable piezoelectric poly (L-lactic acid) (PLLA) nanofibers

    Degradable piezoelectric materials possess significant potential for application in the realm of bone tissue regeneration. However, the correlation between cell regulation mechanisms and the dynamic variation ...

    Yimeng Zhang, Song Chen, Chenjun Huang, Yujie Dai in Biomedical Engineering Letters (2024)

  9. No Access

    Article

    Reciprocal regulation of T follicular helper cells and dendritic cells drives colitis development

    The immunological mechanisms underlying chronic colitis are poorly understood. T follicular helper (TFH) cells are critical in hel** B cells during germinal center reactions. In a T cell transfer colitis model,...

    Xue Bai, Sijie Chen, **nxin Chi, Bowen **e, **nyi Guo, Han Feng in Nature Immunology (2024)

  10. No Access

    Article

    Enhanced biogas upgrading by photocatalytic conversion of carbon dioxide to methane by Methanosarcina barkeri–cadmium sulfide biohybrid

    The semiconductive cadmium sulfide (CdS) nanoparticles were coated on the surface of Methanosarcina barkeri (M. barkeri) by self-assembly method to form the M. barkeri-CdS biohybrid in this work. It proved to be ...

    Ziyu Wang, Mingyu Gou, Qiyuan Zheng, Haiyu Xu in Advanced Composites and Hybrid Materials (2024)

  11. Article

    Open Access

    De novo biosynthesis of β-arbutin in Corynebacterium glutamicum via pathway engineering and process optimization

    β-Arbutin, a hydroquinone glucoside found in pears, bearberry leaves, and various plants, exhibits antioxidant, anti-inflammatory, antimicrobial, and anticancer effects. β-Arbutin has wide applications in the ...

    Bin Zhang, Kexin Gou, Kexin Xu, Zhimin Li in Biotechnology for Biofuels and Bioproducts (2024)

  12. Article

    Open Access

    Biomechanical analysis of trunk and lower limbs during stair activity in patients with scoliosis

    Staircases are a frequently encountered obstacle in daily life, requiring individuals to navigate ascending and descending movements that place additional demands on the trunk and lower limbs compared to walki...

    Yanyun Gou, **g Tao, Jia Huang, Huangwei Lei, **ang Chen in Scientific Reports (2024)

  13. Article

    Open Access

    Distribution and molecular characterization of carbapenemase-producing gram-negative bacteria in Henan, China

    This study aimed to investigate the epidemiological characteristics and trends over time of carbapenemase-producing (e.g., KPC, NDM, VIM, IMP, and OXA-48) Gram-negative bacteria (CPGNB). Non-duplicated multi-d...

    Chenyu Li, Ruyan Chen, Jie Qiao, Haoyu Ge, Lei Fang, Ruishan Liu in Scientific Reports (2024)

  14. No Access

    Article

    One-pot Hydrothermal Synthesis of Bifunctional Co/Mo-rGO efficient Electrocatalyst for HER/OER in Water Splitting

    Fabrication of highly efficient and earth-abundant bifunctional electrocatalyst to accelerate the hydrogen evolution reaction (HER) and oxygen evolution reaction (OER) are critical for overall water splitting....

    Lishuang Zhao, Siyan Liu, Liguo Wei, Huiyi He, Bo Jiang, Zhaoshun Zhan in Catalysis Letters (2024)

  15. Article

    Open Access

    Intein-mediated temperature control for complete biosynthesis of sanguinarine and its halogenated derivatives in yeast

    While sanguinarine has gained recognition for antimicrobial and antineoplastic activities, its complex conjugated structure and low abundance in plants impede broad applications. Here, we demonstrate the compl...

    Yuanwei Gou, Dongfang Li, Minghui Zhao, Mengxin Li, Jiaojiao Zhang in Nature Communications (2024)

  16. Article

    Open Access

    DcR3-associated risk score: correlating better prognosis and enhanced predictive power in colorectal cancer

    Decoy receptor 3 (DcR3), a novel soluble protein belonging to the tumor necrosis factor receptor (TNFR) family, has been previously associated with tumorigenesis in various cancers. However, in our study, we u...

    Ying Duan, Hangrong Fang, Juanhong Wang, Banlai Ruan, Juan Yang in Discover Oncology (2024)

  17. No Access

    Article

    Optimization of edge server group collaboration architecture strategy in IoT smart cities application

    With the development of big data and communication technologies, the Internet of Things (IoT) has permeated all aspects of smart cities. IoT smart city application scenarios are distributed with a large number...

    Fangfang Gou, Jia Wu in Peer-to-Peer Networking and Applications (2024)

  18. No Access

    Article

    Maize auxin response factor ZmARF1 confers multiple abiotic stresses resistances in transgenic Arabidopsis

    Prolonged exposure to abiotic stresses causes oxidative stress, which affects plant development and survival. In this research, the overexpression of ZmARF1 improved tolerance to low Pi, drought and salinity stre...

    Ling Liu, Ying Gong, Baba Salifu Yahaya, Yushu Chen, Dengke Shi in Plant Molecular Biology (2024)

  19. Article

    Open Access

    Integration of transcriptomics, metabolomics, and hormone analysis revealed the formation of lesion spots inhibited by GA and CTK was related to cell death and disease resistance in bread wheat (Triticum aestivum L.)

    Wheat is one of the important grain crops in the world. The formation of lesion spots related to cell death is involved in disease resistance, whereas the regulatory pathway of lesion spot production and resis...

    Cong Li, Lei Yan, Qian Liu, Rong Tian, Surong Wang in BMC Plant Biology (2024)

  20. Article

    Open Access

    Parathyroid hormone (1–34) retards the lumbar facet joint degeneration and activates Wnt/β-catenin signaling pathway in ovariectomized rats

    Facet joint degeneration (FJD) is a major cause of low back pain. Parathyroid hormone (PTH) (1–34) is commonly used to treat osteoporosis. However, little is known about its effects on FJD induced by estrogen ...

    Yu Gou, Hetong Li, Xun Sun, Desheng Chen in Journal of Orthopaedic Surgery and Research (2024)

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