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2,341 Result(s)
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Article
A fast DBSCAN algorithm using a bi-directional HNSW index structure for big data
The Density Based Spatial Clustering of Applications with Noise (DBSCAN) algorithm is one of the most popular and effective density-based clustering algorithms at present. Although it can effectively identify ...
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Article
Open AccessAntiviral activity of luteolin against porcine epidemic diarrhea virus in silico and in vitro
Porcine epidemic diarrhea virus (PEDV) mainly causes acute and severe porcine epidemic diarrhea (PED), and is highly fatal in neonatal piglets. No reliable therapeutics against the infection exist, which poses...
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Article
Gapr for large-scale collaborative single-neuron reconstruction
Whole-brain analysis of single-neuron morphology is crucial for unraveling the complex structure of the brain. However, large-scale neuron reconstruction from terabyte and even petabyte data of mammalian brain...
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Open AccessRelationship between plasma TNF-α levels and agitation symptoms in first episode patients with schizophrenia
Increasing evidence suggested that immune abnormalities involved in the pathophysiology of schizophrenia. However, the relationship between immunity and clinical features has not been clarified. The aim of thi...
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A Semi-Supervised Model for Fine-Grained Identification of Oil Emulsions on the Sea Surface Using Hyperspectral Imaging
After oil spills occur in the ocean, oil pollutants usually appear in the form of oil emulsions under the influence of hydrodynamics. Hyperspectral remote sensing technology, which provides abundant spectral i...
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Solid solution strategy modulated defects engineering of (Cr1-xVx)2AlC MAX phase toward superior electromagnetic wave absorption
Defects engineering is an effective strategy for manipulating electromagnetic parameters and enhancing electromagnetic wave (EMW) absorption capacity. However, the relationship between them is not clear, espec...
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Article
Representation separation adversarial networks for cross-modal retrieval
Cross-modal retrieval aims to search the semantically similar instances from the other modalities by giving a query from one modality. Recently, generative adversarial networks (GANs) has been proposed to mode...
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Dynamic regulation of stem cell adhesion and differentiation on degradable piezoelectric poly (L-lactic acid) (PLLA) nanofibers
Degradable piezoelectric materials possess significant potential for application in the realm of bone tissue regeneration. However, the correlation between cell regulation mechanisms and the dynamic variation ...
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Reciprocal regulation of T follicular helper cells and dendritic cells drives colitis development
The immunological mechanisms underlying chronic colitis are poorly understood. T follicular helper (TFH) cells are critical in hel** B cells during germinal center reactions. In a T cell transfer colitis model,...
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Enhanced biogas upgrading by photocatalytic conversion of carbon dioxide to methane by Methanosarcina barkeri–cadmium sulfide biohybrid
The semiconductive cadmium sulfide (CdS) nanoparticles were coated on the surface of Methanosarcina barkeri (M. barkeri) by self-assembly method to form the M. barkeri-CdS biohybrid in this work. It proved to be ...
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Open AccessDe novo biosynthesis of β-arbutin in Corynebacterium glutamicum via pathway engineering and process optimization
β-Arbutin, a hydroquinone glucoside found in pears, bearberry leaves, and various plants, exhibits antioxidant, anti-inflammatory, antimicrobial, and anticancer effects. β-Arbutin has wide applications in the ...
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Open AccessBiomechanical analysis of trunk and lower limbs during stair activity in patients with scoliosis
Staircases are a frequently encountered obstacle in daily life, requiring individuals to navigate ascending and descending movements that place additional demands on the trunk and lower limbs compared to walki...
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Open AccessDistribution and molecular characterization of carbapenemase-producing gram-negative bacteria in Henan, China
This study aimed to investigate the epidemiological characteristics and trends over time of carbapenemase-producing (e.g., KPC, NDM, VIM, IMP, and OXA-48) Gram-negative bacteria (CPGNB). Non-duplicated multi-d...
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One-pot Hydrothermal Synthesis of Bifunctional Co/Mo-rGO efficient Electrocatalyst for HER/OER in Water Splitting
Fabrication of highly efficient and earth-abundant bifunctional electrocatalyst to accelerate the hydrogen evolution reaction (HER) and oxygen evolution reaction (OER) are critical for overall water splitting....
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Open AccessIntein-mediated temperature control for complete biosynthesis of sanguinarine and its halogenated derivatives in yeast
While sanguinarine has gained recognition for antimicrobial and antineoplastic activities, its complex conjugated structure and low abundance in plants impede broad applications. Here, we demonstrate the compl...
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Open AccessDcR3-associated risk score: correlating better prognosis and enhanced predictive power in colorectal cancer
Decoy receptor 3 (DcR3), a novel soluble protein belonging to the tumor necrosis factor receptor (TNFR) family, has been previously associated with tumorigenesis in various cancers. However, in our study, we u...
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Optimization of edge server group collaboration architecture strategy in IoT smart cities application
With the development of big data and communication technologies, the Internet of Things (IoT) has permeated all aspects of smart cities. IoT smart city application scenarios are distributed with a large number...
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Maize auxin response factor ZmARF1 confers multiple abiotic stresses resistances in transgenic Arabidopsis
Prolonged exposure to abiotic stresses causes oxidative stress, which affects plant development and survival. In this research, the overexpression of ZmARF1 improved tolerance to low Pi, drought and salinity stre...
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Open AccessIntegration of transcriptomics, metabolomics, and hormone analysis revealed the formation of lesion spots inhibited by GA and CTK was related to cell death and disease resistance in bread wheat (Triticum aestivum L.)
Wheat is one of the important grain crops in the world. The formation of lesion spots related to cell death is involved in disease resistance, whereas the regulatory pathway of lesion spot production and resis...
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Open AccessParathyroid hormone (1–34) retards the lumbar facet joint degeneration and activates Wnt/β-catenin signaling pathway in ovariectomized rats
Facet joint degeneration (FJD) is a major cause of low back pain. Parathyroid hormone (PTH) (1–34) is commonly used to treat osteoporosis. However, little is known about its effects on FJD induced by estrogen ...