39 Result(s)
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Bioinformatics
Biomedicine, general
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Protocol
DNA Methylation in Atrial Fibrillation and Its Potential Role in Precision Medicine
Atrial fibrillation (AF), a common arrhythmia, can cause many serious consequences, including stroke and even death. The pathological mechanism of AF is very complicated. Epigenetic mechanisms, especially DNA ...
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Precise Drug Sequential Therapy Can Improve the Cardioversion Rate of Atrial Fibrillation with Valvular Disease after Radiofrequency Ablation
Objective: Based on pathogenesis of atrial fibrillation (AF), investigate the effects of precision drugs continuous therapy on AF cardioversion rate after radiofrequency catheter ablation. Methods: We included 13...
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T Cell Receptor Repertoire Sequencing
The status of T cell receptors (TCRs) repertoire is associated with the occurrence and progress of various diseases and can be used in monitoring the immune responses, predicting the prognosis of disease and o...
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Research Progress in Pathogenesis of Total Anomalous Pulmonary Venous Connection
Congenital heart defect (CHD) is one of the most common birth defects and the leading course of infant mortality. Total anomalous pulmonary venous connection (TAPVC) is a rare type of cyanotic which accounting...
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The Clinical Significance of Microsatellite Instability in Precision Treatment
The recent years have seen the high heterogeneity of colorectal cancer (CRC) receiving increasing attention and being revealed step by step. Microsatellite instability (MSI), characterized by the dysfunction o...
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Genome Variation and Precision Medicine in Systemic Lupus Erythematosus
Systemic lupus erythematosus (SLE) is a complex autoimmune disease which is facing the difficulties in treatment. Genetics play an important role in SLE. Several studies have shown that genetic factors not onl...
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Diagnosis and Treatment of Breast Cancer in the Precision Medicine Era
Breast cancer is one of the most leading causes of death for women worldwide. According to statistics published by the International Agency for Research on Cancer (IARC), the incidence of breast cancer is on t...
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Progress of Clinical Application for Ex Vivo Lung Perfusion (EVLP) in Lung Transplantation
In recent years, medical advances make lung transplantation become a standard treatment for terminal lung diseases (such as emphysema, pulmonary fibrosis, pulmonary cystic fibrosis, and pulmonary arterial hype...
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Recent Advances in DNA Repair Pathway and Its Application in Personalized Care of Metastatic Castration-Resistant Prostate Cancer (mCRPC)
Prostate cancer (PCa) is one of the common malignancies in male adults. In the era of precision medicine, many other novel agents targeting advanced prostate cancer, especially metastatic castration-resistant ...
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Epstein–Barr Virus DNA in Nasopharyngeal Carcinoma: A Brief Review
Epstein–Barr virus (EBV) is a B-lymphocytes herpes virus and can transform B lymphocytes to malignant tumor cells if infected. Nasopharyngeal carcinoma (NPC) is strongly associated with EBV. Circulating EBV DN...
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A Review on Cancer of Unknown Primary Origin: The Role of Molecular Biomarkers in the Identification of Unknown Primary Origin
The primary site cannot be found after clinical and pathological evaluation, which are called cancers of unknown primary origin (CUP). CUPs may resemble a specific primary tumor site which shares common clinic...
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PCSK9 Inhibition and Atherosclerosis: Current Therapeutic Option and Prospection
Low-density lipoprotein cholesterol (LDL-C) is a pivotal factor in atherosclerotic cardiovascular disease (ASCVD), the leading cause of worldwide mortality. The limitations of statin therapy require alternativ...
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Precision Medicine and Dilated Cardiomyopathy
As the most common cardiomyopathy, dilated cardiomyopathy (DCM) is currently defined as a heart muscle disease which is characterized by left ventricular (LV) or biventricular dilation and systolic dysfunction...
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Nanopore Sequencing and Its Clinical Applications
Nanopore sequencing is a method for determining the order and modifications of DNA/RNA nucleotides by detecting the electric current variations when DNA/RNA oligonucleotides pass through the nanometer-sized ho...
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Airway Inflammation Biomarker for Precise Management of Neutrophil-Predominant COPD
Chronic obstructive pulmonary disease (COPD) course can be divided into stable stage and acute exacerbation. Deepen the understanding to the function and role of airway inflammatory cells in stable COPD is imp...
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Applications of Network Analysis in Biomedicine
The abundance of high-throughput data and technical refinements in graph theories have allowed network analysis to become an effective approach for various medical fields. This chapter introduces co-expression...
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Precision Medicine in Tissue Engineering on Bone
With the rapidly development of clinical treatments, precision medicine has come to people eyes with the requirement according to different people and different disease situation. So precision medicine is call...
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Application and Analysis of Biomedical Imaging Technology in Early Diagnosis of Breast Cancer
Breast cancer is the primary malignant tumor that endangers women’s health. The incidence of breast cancer is increasing rapidly in recent years. Accurate disease evaluation before treatment is the key to the ...
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Methylation in Lung Cancer: A Brief Review
Despite the introduction of low-dose computed tomography (LDCT) and implementation of lung cancer screening programs, lung cancer still maintains the leading cause of cancer-specific death all around the world...
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Knowledge Graphs and Their Applications in Drug Discovery
Knowledge graphs represent information in the form of entities and relationships between those entities. Such a representation has multiple potential applications in drug discovery, including democratizing acc...
