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Chapter and Conference Paper
Characterization of Fibronectin Assembly by Adherent Platelets Under Flow Conditions: Effect of Shear Stress and Role of β3 Integrins
Platelet thrombi at site of vascular injury require resistance to shear stress generated by the flowing blood. Fibronectin assembly can contribute to platelet adhesion and aggregation. Here, we examined the ef...
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Chapter and Conference Paper
Shear-Induced Fibrillar-Like Supramolecule of Plasma Fibronectin: A New Form of Fibronectin with Enhanced Activity in Platelet Adhesion and Aggregation
Plasma fibronectin (FN) is synthesized by hepatocytes and secreted into the circulation in a soluble, compact and non-fibrillar form. However, intrinsic functions of FN in the body are prevalent to the multime...