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Chapter and Conference Paper
Allele Frequencies at the D2S44, D10S28 and D14S13 Loci in Four Southern African Populations
Polymorphic DNA arising from variations in the number of short tandem repeats accounts for many of the hypervariable regions detected in the human genome (Nakumura et. al., 1987). For this preliminary study we...
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Chapter and Conference Paper
False Paternity Trios in white, black and Cape Coloured populations
The populations of the Western Cape region are mainly white, black (Xhosa) and the Cape Coloured (CC). The CC population are of mixed genetic background, from white, black, Khoisan and Oriental (Malay) origins...
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Chapter and Conference Paper
DNA Ty** — Strategies in Paternity and Forensic Casework
Since 1972 we have tested 7272 cases of doubtful paternity. Most cases were adequately resolved by testing the conventional red cell antigen, plasma protein, red cell enzyme and HLA polymorphisms. During the l...
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Chapter and Conference Paper
Polymorphism of HLA-DRB3 and DRB4 Genes Detected by RFLPs
All the characterized human HLA class II genes are encoded within the major histocompatibility complex (MHC) on the short arm of chromosome six. Among the five subregions of the class II region, HLA-DR is uniq...
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Chapter and Conference Paper
The Generation of Class II Polymorphism by Recombination
One of the most striking features of the HLA gene products is their high degree of polymorphism. The HLA class II polymorphism varies from locus to locus, e.g. at present there are 18 serological defined antig...
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Chapter and Conference Paper
Evolutions of the Immune System
Determining the relative importance of the elements of the immune sytem is a major task to which comparative studies may help first in pointing to key elements and second in suggesting their phylogenetic origi...
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Chapter and Conference Paper
T Cell Differentiation in Lower Vertebrates
With all the recent advances in the study of T cell differentiation in mice, it is reasonable to question whether anything can be fetched from the examination of this problem in lower vertebrates. One obvious ...