-
Article
Extensive polymorphism of the FUT2 gene in an African (Xhosa) population of South Africa
The human secretor type α(1,2)fucosyltrans-ferase gene (FUT2) polymorphism was investigated in Xhosa and Caucasian populations of South Africa by polymerase chain reaction–restriction fragment length polymorphism...
-
Article
Five novel missense mutations of the Lewis gene (FUT3) in African (Xhosa) and Caucasian populations in South Africa
Five novel missense mutations, viz., C304 A, T370 G, G484 A, G667 A, and G808 A, in the Lewis gene (FUT3) were detected in African (Xhosa) and Caucasian individuals in South Africa. These single base substitutio...
-
Chapter and Conference Paper
The Generation of Class II Polymorphism by Recombination
One of the most striking features of the HLA gene products is their high degree of polymorphism. The HLA class II polymorphism varies from locus to locus, e.g. at present there are 18 serological defined antig...
-
Chapter
The Heterogeneity of HLA-DR2
In 1978, Richiardi and co-workers first reported the division of HLA-DR2 into two subtypic specificities, named T060 and T061 (1). Several authors have since reported splits of DR2 (2). During the Ninth Intern...
-
Chapter
HLA-DRw6 and Its Complexity
HLA-DRw6 was first defined during the Seventh Workshop, but its definition remained difficult after the Eighth Workshop (1). During the Ninth Workshop the existence of subgroups, i.e., DRw13 and DRw14 was acce...
