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Chapter and Conference Paper
Allele Frequencies at the D2S44, D10S28 and D14S13 Loci in Four Southern African Populations
Polymorphic DNA arising from variations in the number of short tandem repeats accounts for many of the hypervariable regions detected in the human genome (Nakumura et. al., 1987). For this preliminary study we...
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Chapter and Conference Paper
False Paternity Trios in white, black and Cape Coloured populations
The populations of the Western Cape region are mainly white, black (Xhosa) and the Cape Coloured (CC). The CC population are of mixed genetic background, from white, black, Khoisan and Oriental (Malay) origins...
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Chapter and Conference Paper
PGM1 Subty** by Isoelectric Focusing (IEF) in Parentage Testing in South African (SA) Populations
PGM1 is an ubiquitous enzyme which is coded for by a gene situated on chromosome 1p. PGM1 reversibly catalyses the transfer of phosphate from the first to the sixth position of glucose in the glycolytic pathwa...
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Chapter and Conference Paper
Parentage Testing Using DBP Subty** in South African (SA) Populations
The vitamin D binding protein (DBP) of human plasma, also referred to as group specific component (GC), was first described by Hirschfeld in 1959. One of its major functions is to act as a transport protein fo...
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Chapter and Conference Paper
RFLP Standardization Report for DR Alpha/KpnI
Four bands were identified by the RFLP analysis in the DR alpha/KPN system as shown in Table 1 and in Figure 1. RFLP patterns of the core cell lines are shown in Table 2.
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Chapter and Conference Paper
Antigen Society #26 Report (DR3, DR7, DQw2): Part 1
There were 1,019 cells analyzed in the Antigen Society (795 Caucasians, 202 Negroes, 22 Orientals); 1,011 were tested both on Core serology and Antigen Society reagents. The total number of sera and monoclonal...
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Chapter and Conference Paper
Antigen Society #12 Report (Bw54, Bw55, Bw56 and Bw42)
The antigen Bw54 was officially designated as a split of Bw22 at the Seventh International Histocompatibility Workshop. This antigen was primarily defined in the Japanese population by several laboratories ind...
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Chapter and Conference Paper
Antigen Society #18 Report (Cw4 and Cw6)
HLA-Cw4 (formerly T4, RH315) and HLA-Cw6 (formerly T7) obtained the formal HLA designation after the Sixth and Seventh International Histocompatibility Workshops respectively (1,2). Since then, it has been obs...
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Chapter and Conference Paper
Southern Blot Analysis of Rheumatoid Arthritis
The methods and materials used in the Southern blot analysis of rheumatoid arthritis (RA) study were identical to the conditions used in the core and family study sections of the Tenth Workshop (10WS) Southern...
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Chapter and Conference Paper
Antigen Society #25 Report DRw6, DRw13, DRw14)
Since the Ninth International Histocompatibility Workshop 1984, two splits of HLA-DRw6 have been recognized: DRw13 and DRw14(1). Both specificities were included in DRw52 and highly associated with DQw1. At th...
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Chapter and Conference Paper
Antigen Society #7 Report (B8, w59, B14, w64, w65)
HLA B8 and HLA B14 have been well established specificities since 1965 (1) and 1970 (2), respectively. Bw59, restricted to the Oriental population, was defined in 1980 (3), and the B14 subtypes Bw64 and Bw65 w...
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Article
Evidence for subtypic determinants in the HLA-DW3 cluster
This study was undertaken to get more insight into the previously suggested heterogeneity of the HLA-DW3 cluster. Preliminary evidence of DW3 heterogeneity was derived from results of intrafamilial mixed lymph...