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Chapter and Conference Paper
Quantitative Analyse der Mikrozirkulation von Wunden mit OPS imaging
Introduction: Orthogonal polarization spectral (OPS) imaging, implemented into the CYTOSCAN A/R, is a new, recently introduced technique to produce high contrast images of the microcirculation wi...
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Chapter and Conference Paper
The Study of the Microcirculation using Orthogonal Polarization Spectral Imaging
The microcirculation is an extremely important part of the body where blood interacts with tissue to create an environment necessary for cell survival [1]. As such, an understanding of its function under both ...
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Chapter and Conference Paper
Validierung des „OPS imaging“ Verfahrens an der Rattenleber
Hintergrund: Störungen der hepatischen Mikrozirkulation sind wesentlich an der Pathophysiologie der postischämischen Organdysfunktion nach Leberchirurgie sowie Trans-plantation beteiligt. Die qua...
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Chapter and Conference Paper
Langzeitkonservierung mit UW versus EC verbessert die Revaskularisierung des transplantierten Knochens
Zur Überbrückung langstreckiger Röhrenknochendefekte und zur Wiederherstellung der Gelenkfunktion nach Trauma wurde durch die allogene Transplantation vaskularisierter Knochen und Gelenke eine neue Behandlungs...
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Chapter and Conference Paper
Oxaceprol reduziert die Leukozyten-Adhärenz und -Extravasation und erhält die Perfusion des Gewebes nach Ischämie/Reperfusion (I/R) aufrecht
Akkumulation von Leukozyten, Beeinträchtigung der Perfusion sowie Steigerung der Permeabilität kennzeichnen den mikrovaskulären Ischämie/Reperfusions (I/R)-Schaden. Das Antiphlogistikum Oxaceprol ist zugelasse...
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Chapter and Conference Paper
Receptors and Their Modulation
The potential for hormonal intervention in cancer was identified as early as 1895, even before the concept of hormones was established. Indeed, we know that the first hormone was discovered only in 1902 (secre...
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Chapter and Conference Paper
Heart Size Reduction in Acromegalic Patientes Treated with the Long-Acting Somatostatin-Analogue SMS 201–995 (Somatostatin®)
Cardiomegaly by hypertrophy of the heart in acromegalic patients — prevalence 85% in our patients with acromegaly [1] — is often complicated by complex arrhythmias and gradual cardiac-insufficiency [1, 3, 8]. ...
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Chapter and Conference Paper
Effects of Long-Term Administration of Sandostatin® (SMS 201–995) at Increasing Doses in 40 Acromegalic Patients. Results from the French Sandostatin Acromegaly Study Group
Several studies demonstrate the efficacy of short- and long-term Sandostatin® treatment in acromegaly administered subcutaneously at doses ranging from 150 to 300 µg up to 600 µg per day [1, 3, 5, 7–10]. A rhythm...
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Chapter and Conference Paper
Observations During a Clinical Trial of Sandostatin® in Acromegalic Patients
Ten acromegalic patients were studied over a period of 75 weeks. Four had had one or more attempted ablations of their pituitary adenoma, six were previously untreated or had been unsuccessfully treated with b...
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Chapter and Conference Paper
Long-Term Treatment of Acromegaly by Continuous Subcutaneous Infusion of the Long-Acting Somatostatin Analog Sandostatin® (SMS 201–995, Octreotide)
Recently the long-acting somatostatin analog Sandostatin® (SMS 201–995, Octreotide) was introduced for the therapy of acromegaly. On a two or three daily subcutaneous (s.c.) injection regimen plasma GH levels hav...
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Chapter and Conference Paper
Long-Term Efficacy of Sandostatin®(SMS 201–995, Octreotide) in 178 Acromegalic Patients. Results from the International Multicentre Acromegaly Study Group
Sandostatin® (SMS 201–995), a synthetic long-acting octapeptide, represents an efficacious alternative therapeutic candidate to available treatment modalities for acromegaly.