29 Result(s)
within
Chapter
T. L. **
Internal Medicine
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Chapter
Precision Medicine in the Intensive Care Unit: Identifying Opportunities and Overcoming Barriers
Is precision medicine really precise? Precision in medicine can only be achieved with precision diagnostics. Unfortunately, barriers such as access to clean electronic medical data, accurate and precise labora...
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Acute Ear Emergencies
The emergency department is often the first port of call for a variety of ear, nose and throat (ENT) disorders. Although most of these conditions are benign, there are important critical ENT disorders that mus...
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Acute Nose Disorders
The nose being highly vascular with communications with intracranial venous sinuses, it is highly prone for emergencies due to trauma, infections and allergy.
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Acute Throat Disorders
Sore throat is a common complaint in the emergency department and is often associated with benign conditions, such as pharyngitis. The neck and throat are regions rich in vascular and lymphatic activity. They ...
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Skin Necrosis and the Need for Vascular Assessments
There are many causes of skin necrosis. The process resulting in skin necrosis begins with the sudden thrombotic occlusion of single or multiple blood vessels supplying the tissue. Compromised blood vessels le...
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Emerging Role of Computed Tomography Angiography in the Evaluation of Coronary Atherosclerosis
Over the past decade, coronary computed tomographic angiography (CCTA) has broadened the diagnostic ability of physicians by providing a means to non-invasively image coronary atherosclerosis. It provides a ro...
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Clinical Role of Antiarrhythmic Drugs in the Prevention of Sudden Death
The role of antiarrhythmic drugs for prevention of sudden cardiac death has changed dramatically in the past 20 years. Though antiarrhythmics were once considered first-line therapy for the prevention of sudde...
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Hypertension and Stroke in Racial/Ethnic Groups
The impact of hypertension is a major contributor to the largely uncontrolled, global disease burden across all racial/ethnic groups. African-Americans have a higher incidence and prevalence of hypertension co...
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Chapter and Conference Paper
Initial ICU Management of Skin Sloughing Diseases: Toxic Epidermal Necrolysis and Stevens-Johnson Syndrome
Case Presentation: A 48 year old woman with metastatic breast cancer develops signs of an upper respiratory infection, fever, and malaise two weeks after starting dilantin for seizures from brain metastases. I...
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Chapter and Conference Paper
Initial ICU Management of Skin Sloughing Diseases: Toxic Epidermal Necrolysis and Stevens-Johnson Syndrome
Case Presentation: A 48 year old woman with metastatic breast cancer develops signs of an upper respiratory infection, fever, and malaise two weeks after starting dilantin for seizures from brain metastases. I...
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Cloning and Regulation of Peroxisome Proliferator-Induced Acyl-CoA Thioesterases From Mouse Liver
1.1. Acyl-CoA thioesterases hydrolyze acyl-CoAs to the corresponding free fatty acid plus CoASH. The activity is strongly induced in rat and mouse liver after feeding the animals peroxisome proliferators. To e...
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Chapter and Conference Paper
Potential of Motilides in the Treatment of Hypomotility Syndromes
The 22-amino-acid polypeptide motilin was discovered as a result of the study of the relationship between changes in duodenal pH and gastric motility (Brown et al. 1966, 1972). As soon as the synthesis of the ...
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Receptor-specific Regulation of NF-κB, c-Myc and Fas-mediated Apoptosis in Primary B Cells
The NF-κB transcription factor complex plays a role in directing the inducible expression of a number of genes involved in the immune response, importantly including c-myc [1]. NF-κB consists of homo- or hetero-d...
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Guidelines for designing an endoscopy unit (Report of the Dutch Society of Hepatogastroenterology)
In many hospitals endoscopy was first introduced by performing gastroscopies in an all-purpose, empty room. The rapid development of endoscopy with all its diagnostic and therapeutic possibilities gave rise to...
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Chapter and Conference Paper
Therapy in Barrett’s Esophagus: Medical Treatment Versus Antireflux Surgery
Barrett’s columnar lined esophagus (CLO) has a marked propensity to develop serious complications [1]. In more than 50% of patients there is an associated stricture or ulceration, and tendency to hemorrhage, p...
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The Spinal Actions of Opioids
An important site of action of opioids lies within the spinal cord. Receptor systems identified in this region have been shown to exert significant regulatory control over sensory, autonomic, and somatomotor f...
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Opioid Receptor Multiplicity: Isolation, Purification, and Chemical Characterization of Binding Sites
This chapter will deal primarily with what researchers have been able to learn about the properties of opioid receptors, or more precisely, of opioid binding sites, by isolating and purifying them. In order to...
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Chapter and Conference Paper
Free Radical Activity in Chronic Ethanol Intoxication in Humans
Chronic ethanol poisoning is probably the commonest chemical intoxication in the world and yet one of the least understood. It can also be one of the most difficult diseases to diagnose in clinical practice. M...
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Pathogenesis and Immunology in Shigellosis: Applications for Vaccine Development
Although the immunological basis of protection from shigellosis is poorly understood, it is likely that secretory immunoglobulin A (IgA) on mucosal surfaces and mucosal lymphocytes in the intestine play import...
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Autoradiographic Measurement of the Rate of Serotonin Synthesis in the Rat Brain
The rate of serotonin synthesis has hitherto been measured by two different methodological approaches, steady- and nonsteady-state. In these methods, the rate of synthesis is estimated from the change in the c...
