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An insight into the therapeutic effects of isoliquiritigenin in breast cancer
Breast cancer ranks as the most widespread malignant condition in women, emerging as a primary contributor to mortality. The primary challenges in...
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Outpatient reception via collaboration between nurses and a large language model: a randomized controlled trial
Reception is an essential process for patients seeking medical care and a critical component influencing the healthcare experience. However, current...
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Clinical features and underlying etiology of children with Lennox–Gastaut syndrome
ObjectiveLennox–Gastaut Syndrome (LGS) is characterized by the presence of multiple seizure types and encompasses a heterogenous group of etiologies....
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Lessons from the physiological role of guanosine in neurodegeneration and cancer: Toward a multimodal mechanism of action?
Neurodegenerative diseases and brain tumours represent important health challenges due to their severe nature and debilitating consequences that...
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A Translational Approach to Using Endocannabinoid Modulators for Targeting Opioid-Associated Memory
Purpose of ReviewIt is well established that learning and memory are central to substance dependence. Convincing basic and clinical documents...
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Transcriptomic profiling and discovery of key transcription factors involved in adventitious roots formation from root cuttings of mulberry
ARs plays a crucial role in plant morphogenesis and development. The limited and inefficient rooting of scions poses a significant challenge to the...
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Circular walking is useful for assessing the risk of falls in early progressive supranuclear palsy
BackgroundProgressive supranuclear palsy (PSP) is characterized by early onset postural instability and frequent falls. Circular walking necessitates...
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Digital outcome measures are associated with brain atrophy in patients with multiple sclerosis
BackgroundDigital monitoring of people with multiple sclerosis (PwMS) using smartphone-based monitoring tools is a promising method to assess disease...
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Methane-rich saline ameliorates depressive-like behaviors during chronic unpredictable mild stress (CUMS)
Depression, considered the most prevalent neuropsychiatric disorder, is multifactorial and complex. Oxidative stress and inflammation significantly...
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Mitochondrial DNA abundance in blood is associated with Alzheimer’s disease- and dementia-risk
The mitochondrial cascade hypothesis of Alzheimer’s disease (AD) has been portrayed through molecular, cellular, and animal studies; however large...
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Critical Care of Spinal Cord Injury
Purpose of ReviewSpinal cord injury (SCI) is a major cause of morbidity and mortality, posing a significant financial burden on patients and the...
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Pandemic Paranoia Scale for Adolescents (PPS-A): An Initial Psychometric Evaluation and Prevalence Study of Adolescents in the United States and United Kingdom
Paranoid thoughts have been reported in 20–30% of adolescents, and preliminary research has shown that paranoia and psychotic-like experiences have...
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Progressive multifocal leukoencephalopathy and spectrum of predisposing conditions: a 20-year retrospective cohort study in a tertiary center in São Paulo, Brazil
BackgroundEpidemiological studies on predisposing conditions and outcomes of progressive multifocal leukoencephalopathy (PML) cases have been carried...
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Embelin Mitigates Amyloid-β-Induced Neurotoxicity and Cognitive Impairment in Rats: Potential Therapeutic Implications for Alzheimer’s Disease
Alzheimer’s disease (AD) is a significant form of dementia. Embelin (EMB) is a natural compound with varied actions that could help prevent AD...
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ESF1 and MIPEP proteins promote estrogen receptor-positive breast cancer proliferation and are associated with patient prognosis
BackgroundEstrogen receptor-positive (ER+) breast cancer accounts for two-thirds of all breast cancers, and its early and late recurrences still...
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Post-implantation analysis of genomic variations in the progeny from develo** fetus to birth
The analysis of genomic variations in offspring after implantation has been infrequently studied. In this study, we aim to investigate the extent of de...
