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Redundancy in microbiota-mediated suppression of the soybean cyst nematode
BackgroundSoybean cyst nematodes (SCN) as animal parasites of plants are not usually interested in killing the host but are rather focused on...
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Lessons from the physiological role of guanosine in neurodegeneration and cancer: Toward a multimodal mechanism of action?
Neurodegenerative diseases and brain tumours represent important health challenges due to their severe nature and debilitating consequences that...
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Perception of couples’ on multipurpose prevention technology attribute choice: the case of MTN 045
BackgroundMultipurpose prevention technologies (MPTs) are products capable of simultaneously addressing multiple sexual and reproductive health needs...
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Mavorixafor: First Approval
Mavorixafor (XOLREMDI™) is an oral, selective C-X-C chemokine receptor 4 (CXCR4) antagonist developed by X4 Pharmaceuticals that blocks the binding...
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DAP12 interacts with RER1 and is retained in the secretory pathway before assembly with TREM2
DNAX-activating protein of 12 kDa (DAP12) is a transmembrane adapter protein expressed in lymphoid and myeloid lineage cells. It interacts with...
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TOTEM: a multi-cancer detection and localization approach using circulating tumor DNA methylation markers
BackgroundDetection of cancer and identification of tumor origin at an early stage improve the survival and prognosis of patients. Herein, we...
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Influence of Urolithin A and Cholecalciferol on IFN-γ Production by Peripheral Blood Mononuclear Cells Under Normal Conditions and in the Presence of Products Released by Tumor Cells
Urolithin A is a polyphenolic metabolite of ellagic acid and ellagitannins that is produced by intestinal microbiota and has higher bioavailability...
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Risk factors associated with underweight in children aged one to two years: a longitudinal study
BackgroundUnderweight is a prevalent health issue in children. This study aimed to identify factors associated with underweight in children aged 1–2...
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A novel class of indole derivatives: enhanced bioavailability, permeability, and antioxidant efficacy for thromboembolic disease therapy
Free radicals like reactive oxygen species (ROS) and reactive nitrogen species (RNS) cause cellular damage and contribute to thromboembolic diseases...
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A Ratiometric Benzimidazole-Based Fluorescent Probe for The Recognition of Phosgene in Solution and Gaseous Phases
Considering the high toxicity and widespread application of phosgene, there is an urgent need to develop a simple and sensitive method for detecting...
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Autoantibodies Neutralizing GM-CSF in HIV-Negative Colombian Patients Infected with Cryptococcus gattii and C. neoformans
BackgroundCryptococcosis is a life-threatening disease caused by Cryptococcus neoformans or C. gattii . Neutralizing autoantibodies (auto-Abs)...
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The hospital emigration to another region in the light of the environmental, social and governance model in Italy during the period 2004-2021
The following article presents an analysis of the impact of the Environmental, Social and Governance-ESG determinants on Hospital Emigration to...
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Nonadherence to oral cancer chemotherapy in hepatocellular carcinoma: prevalence and predictive factors in Vietnam
PurposeStandard oral cancer chemotherapy (OCT) or targeted therapy (OTT) has expanded the treatment methods for hepatocellular carcinoma (HCC)....
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Willingness to receive mpox vaccine among men who have sex with men: a systematic review and meta-analysis
BackgroundSince May 2022, mpox outbreaks have been occurring in non-mpox endemic areas, with the main population affected being men who have sex with...
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Effects of high-intensity interval training on cardiometabolic biomarkers in patients with prostate cancer undergoing active surveillance: a randomized controlled trial
PurposeTo report the effects of a 12-week high-intensity interval training (HIIT) program on cardiometabolic biomarkers in patients with prostate...
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Enteroviruses: epidemic potential, challenges and opportunities with vaccines
Enteroviruses (EVs) are the most prevalent viruses in humans. EVs can cause a range of acute symptoms, from mild common colds to severe systemic...
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Phytochemical Analysis of Extract and Essential Oil of Echinophora platyloba
Echinophora platyloba DC. is one of the two exclusive species from Iran belonging to the Umbelliferae family. This plant has medicinal properties...
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Design, Synthesis and Biological Evaluation of (Z)-1-(Benzo[D]Thiazol-2-yl)-2-(3-Substituted Thiazolidine-4-One) Hydrazine Dpre1 Inhibitors as Antimycobacterial Agents
A simple and promising methodology was employed for the synthesis of (Z )-1-(benzo[ d ]thiazol-2-yl)-2-(3-substituted thiazolidine-4-one) hydrazine as...
