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Phytochemical Analysis of Extract and Essential Oil of Echinophora platyloba

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Pharmaceutical Chemistry Journal Aims and scope

Echinophora platyloba DC. is one of the two exclusive species from Iran belonging to the Umbelliferae family. This plant has medicinal properties such as antimicrobial, antibacterial, antifungal and is effective in the treatment of premenstrual syndrome. Despite the great medicinal importance of this plant, it has been little studied phytochemically. In this study, E. platyloba plant collected from Chaharmahal and Bakhtiari Province, Iran was examined phytochemically for volatile compounds in the essential oil and natural compounds in the extract. Essential oil of E. platyloba was extracted by hydrodistillation using a Clevenger-type apparatus and analyzed by GC-MS and evaluated qualitatively and quantitatively. The constituents of the essential oil were identified and quantified using the Kovats retention index (KI) and retention time (RT) values, eight-peak information, and reference spectra. The extract of E. platyloba was extracted by maceration and deffated. The obtained extract was analyzed and purified regarding its constituents using column and thin layer chromatography (TLC) techniques. In all, 92.84% of the essential oil of the plant was identified as having the highest concentration of the essential oil of E. platyloba related to monoterpenes (91.77%), while trans-â-ocimene with a concentration of 81.05 as a hydrocarbon monoterpene had the highest concentration in this essential oil. The molecular structure of naringenin (5,7-dihydroxy-2-(4-hydroxyphenyl)chroman-4-one) was identified as a trihydroxy flavanone according to FT-IR, 1H NMR, 13C NMR and DEPT spectroscopy. The results of phytochemical tests showed the presence of flavonoids, tannins and alkaloid compounds in this plant.

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Authors and Affiliations

  1. Department of Phytochemistry and Essential Oils Technology, Faculty of Pharmaceutical Chemistry, Pharmaceutical Sciences Branch, Islamic Azad University (IAUPS), Tehran, Iran

    Mostafa Akbari

  2. Department of Chemistry, Takestan Branch, Islamic Azad University, Takestan, Iran

    Mahboubeh Taherkhani

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  1. Mostafa Akbari
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  2. Mahboubeh Taherkhani
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Correspondence to Mahboubeh Taherkhani.

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Akbari, M., Taherkhani, M. Phytochemical Analysis of Extract and Essential Oil of Echinophora platyloba. Pharm Chem J (2024). https://doi.org/10.1007/s11094-024-03168-0

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