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  1. A comprehensive cancer center in the cloud powered by AI can reduce health disparities

    Wilfred Ngwa, Arthur Pressley, ... Kenneth Ngwa in Nature Medicine
    Article 15 July 2024
  2. Outpatient reception via collaboration between nurses and a large language model: a randomized controlled trial

    Reception is an essential process for patients seeking medical care and a critical component influencing the healthcare experience. However, current...

    Peixing Wan, Zigeng Huang, ... Er** Long in Nature Medicine
    Article 15 July 2024
  3. Panoramic tumor microenvironment in pancreatic ductal adenocarcinoma

    Pancreatic ductal adenocarcinoma (PDAC) is notorious for its resistance to various treatment modalities. The genetic heterogeneity of PDAC, coupled...

    **aoying Li, Wanting Hou, ... Dan Cao in Cellular Oncology
    Article 15 July 2024
  4. Lessons from the physiological role of guanosine in neurodegeneration and cancer: Toward a multimodal mechanism of action?

    Neurodegenerative diseases and brain tumours represent important health challenges due to their severe nature and debilitating consequences that...

    Carla Inês Tasca, Mariachiara Zuccarini, ... Francisco Ciruela in Purinergic Signalling
    Article 15 July 2024
  5. The relationship and clinical significance of lactylation modification in digestive system tumors

    Lactylation, an emerging post-translational modification, plays a pivotal role in the initiation and progression of digestive system tumors. This...

    Gang Wang, **aosu Zou, ... Shenhong Qu in Cancer Cell International
    Article Open access 15 July 2024
  6. Breast cancer preventive practices and associated factors among reproductive age women in Wadila District, North East Ethiopia: community based cross-sectional study

    Background

    Cancer is one of the leading causes of morbidity and mortality worldwide. Among all cancer types, breast cancer stands out as the most...

    Zemene Damtie, Niguss Cherie, Melaku Mekonnen Agidew in BMC Cancer
    Article Open access 15 July 2024
  7. Understanding lactate in the development of Hepatitis B virus-related hepatocellular carcinoma

    Hepatitis B Virus (HBV) is a hepatotropic virus that can establish a persistent and chronic infection in humans. Chronic hepatitis B (CHB) infection...

    Sheida Behzadi Sheikhrobat, Shahab Mahmoudvand, ... Somayeh Shokri in Infectious Agents and Cancer
    Article Open access 15 July 2024
  8. Autoantibodies Neutralizing GM-CSF in HIV-Negative Colombian Patients Infected with Cryptococcus gattii and C. neoformans

    Background

    Cryptococcosis is a life-threatening disease caused by Cryptococcus neoformans or C. gattii . Neutralizing autoantibodies (auto-Abs)...

    Carlos A. Arango-Franco, Julian Rojas, ... Andrés A. Arias in Journal of Clinical Immunology
    Article Open access 15 July 2024
  9. Effects of high-intensity interval training on cardiometabolic biomarkers in patients with prostate cancer undergoing active surveillance: a randomized controlled trial

    Purpose

    To report the effects of a 12-week high-intensity interval training (HIIT) program on cardiometabolic biomarkers in patients with prostate...

    Dong-Woo Kang, Catherine J. Field, ... Kerry S. Courneya in Prostate Cancer and Prostatic Diseases
    Article 15 July 2024
  10. Nonadherence to oral cancer chemotherapy in hepatocellular carcinoma: prevalence and predictive factors in Vietnam

    Purpose

    Standard oral cancer chemotherapy (OCT) or targeted therapy (OTT) has expanded the treatment methods for hepatocellular carcinoma (HCC)....

    Thai Doan Ky, Nguyen Thi Loan, ... Mai Thanh Binh in BMC Cancer
    Article Open access 15 July 2024
  11. TOTEM: a multi-cancer detection and localization approach using circulating tumor DNA methylation markers

    Background

    Detection of cancer and identification of tumor origin at an early stage improve the survival and prognosis of patients. Herein, we...

    Dalin **ong, Tiancheng Han, ... Chunguang Li in BMC Cancer
    Article Open access 15 July 2024
  12. SNCA is a potential therapeutic target for COVID-19 infection in diffuse large B-cell lymphoma patients

    Cuprotosis related genes (CRGs) have been proved to be potential therapeutic targets for coronavirus disease 2019 (COVID-19) and cancer, but their...

    Can Chen, Yun Li, ... Shenxian Qian in Apoptosis
    Article Open access 15 July 2024
  13. Unveiling the PDK4-centered rituximab-resistant mechanism in DLBCL: the potential of the “Smart” exosome nanoparticle therapy

    Background

    Diffuse large B-cell lymphoma (DLBCL) represents a prevalent malignant tumor, with approximately 40% of patients encountering treatment...

    **n Wu, Chunmei Ban, ... Qiangqiang Zhao in Molecular Cancer
    Article Open access 15 July 2024
  14. Associations between quantitative measures of mammographic density and terminal ductal lobular unit involution in Chinese breast cancer patients

    Background

    Higher mammographic density (MD), a radiological measure of the proportion of fibroglandular tissue in the breast, and lower terminal duct...

    Waruiru Mburu, Changyuan Guo, ... **aohong R. Yang in Breast Cancer Research
    Article Open access 15 July 2024
  15. BACH2 regulates diversification of regulatory and proinflammatory chromatin states in TH17 cells

    Interleukin-17 (IL-17)-producing helper T (T H 17) cells are heterogenous and consist of nonpathogenic T H 17 (npT H 17) cells that contribute to tissue...

    Pratiksha I. Thakore, Alexandra Schnell, ... Aviv Regev in Nature Immunology
    Article 15 July 2024
  16. Advancements in pathogen immunity and signaling

    Mads Gyrd-Hansen, Anna Kajaste-Rudnitski, ... Matteo Iannacone in Nature Immunology
    Article 15 July 2024
  17. A life-course multisectoral approach to precision health in LMICs

    Stefan Swartling Peterson, Olive Kobusingye, ... Peter Waiswa in Nature Medicine
    Article 15 July 2024
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