18 Result(s)
within
Article
Zhiwei Zhong
English
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Article
Lin-28 reactivation is required for let-7 repression and proliferation in human small cell lung cancer cells
The let-7 family of microRNAs (miRNAs) are known to act as tumor suppressors and down-regulated in lung cancer. Recently, the RNA-binding protein Lin-28 was demonstrated to inhibit biogenesis of let-7 miRNAs b...
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miR-21 induces cell cycle at S phase and modulates cell proliferation by down-regulating hMSH2 in lung cancer
MicroRNAs regulate critical genes associated with lung cancer. Human mutS homolog 2 (hMSH2), one of the core mismatch repair genes, is affected in lung cancer development. The aim of this study is to investigate ...
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MicroRNA-31-5p modulates cell cycle by targeting human mutL homolog 1 in human cancer cells
MicroRNAs (miRNAs) and DNA mismatch repair (MMR) have been linked to human cancer progression. Human mutL homolog 1 (hMLH1), one of the core MMR genes, defects in lung cancer development. However, the interact...
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CHD1L Expression Increases Tumor Progression and Acts as a Predictive Biomarker for Poor Prognosis in Pancreatic Cancer
The chromodomain helicase/ATPase DNA binding protein 1-like gene (CHD1L) plays a key role in controlling various cellular phenomena, including immune-mediated inflammation, transformation, apoptosis, cell cycl...
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Open AccessLarge herbivores influence plant litter decomposition by altering soil properties and plant quality in a meadow steppe
Large herbivores act as a major driver of plant litter decomposition in grasslands. The modifications of soil biotic and abiotic properties, as well as the changes in quality (C/N ratio) of plant litter, are t...
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DNA computing for combinational logic
With the progressive scale-down of semiconductor’s feature size, people are looking forward to More Moore and More than Moore. In order to offer a possible alternative implementation process, researchers are t...
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Characterization of Calibrated Gelatin Sponge Particles in a Rabbit Renal Embolization Model
To evaluate the level of artery occlusion, degradation periods, tissue response and vessel recanalization of calibrated gelatin sponge particles after segmental renal artery embolization.
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Open AccessLncRNA FTX represses the progression of non-alcoholic fatty liver disease to hepatocellular carcinoma via regulating the M1/M2 polarization of Kupffer cells
The effect of lncRNA FTX on non-alcoholic fatty liver disease (NAFLD) conversion to hepatocellular carcinoma (HCC) is unclear.
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Effects of grazing on C:N:P stoichiometry attenuate from soils to plants and insect herbivores in a semi-arid grassland
Understanding the processing of limiting nutrients among organisms is an important goal of community ecology. Less known is how human disturbances may alter the stoichiometric patterns among organisms from dif...
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Open AccessA convenient polyculture system that controls a shrimp viral disease with a high transmission rate
Develo** ecological approaches for disease control is critical for future sustainable aquaculture development. White spot syndrome (WSS), caused by white spot syndrome virus (WSSV), is the most severe diseas...
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Open AccessStructural basis of tethered agonism of the adhesion GPCRs ADGRD1 and ADGRF1
Adhesion G protein-coupled receptors (aGPCRs) are essential for a variety of physiological processes such as immune responses, organ development, cellular communication, proliferation and homeostasis1–7. An intri...
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Effects of Microporous Packaging Combined with Chitosan Coating on the Quality and Physiological Metabolism of Passion Fruit after Harvest
The postharvest quality of passion fruit deteriorates rapidly because of intense physiological metabolism and serious water loss. It is difficult to solve the problems of water loss and microbial growth of pas...
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Open AccessDevelopment of a prognostic model for anoikis and identifies hub genes in hepatocellular carcinoma
Considering the high fatality of hepatocellular carcinoma (HCC), current prognostic systems are insufficient to accurately forecast HCC patients' outcomes. In our study, nine anoikis‑related genes (PTRH2, ITGA...
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Open AccessClinical application of modified hip joint lateral position in femoral neck fracture
To show the femoral neck better in hip lateral view of X-ray, we design a modified hip lateral view and then investigate the value in femoral neck fractures.
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Open AccessReview of research and control technology of underwater bionic robots
As marine resources continue to be exploited, the remarkable locomotion and coordination of fish provide an excellent source of inspiration for scientists and engineers to design and control the next -generati...
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Standing Litter Modifies Top-Down Effects of Large Herbivores on a Grassland Plant Community
Large herbivores can exert pronounced top-down effects on plant communities in grassland ecosystems. Previous studies highlighted the importance of the composition and traits of living plants in regulating th...
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Proteomic Investigation of Metabolic Changes of Passion Fruit Treated with Microporous Packaging Combined with Chitosan Coating During Storage
In our previous research, microporous packaging combined with chitosan active coating (MP-CH) treatment extended the shelf life of passion fruit at 25 °C to 12 days by regulating water loss and physiological m...
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Open AccessTargeting pro-inflammatory T cells as a novel therapeutic approach to potentially resolve atherosclerosis in humans
Atherosclerosis (AS), a leading cause of cardio-cerebrovascular disease worldwide, is driven by the accumulation of lipid contents and chronic inflammation. Traditional strategies primarily focus on lipid redu...
