26 Result(s)
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Article
Zhen-zhen Li
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Article
Decrease of renal aquaporins 1–4 is associated with renal function impairment in pediatric congenital hydronephrosis
Renal aquaporins (AQP1-4) concentration is downregulated and is in proportion to the degree of hydronephrosis graded by ultrasound in pediatric congenital hydronephrosis (CH). However, the relationship between...
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Firing Pattern Modulation Through SK Channel Current Increase Underlies Neuronal Survival in an Organotypic Slice Model of Parkinson’s Disease
Dopaminergic (DA) neurons in substantia nigra pars compacta (SNc) are vulnerable to excitotoxicity in Parkinson’s disease (PD). Neurotoxic stimuli may alter the firing patterns of DA neurons. However, whether ...
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Open AccessSeismic fluid identification using a nonlinear elastic impedance inversion method based on a fast Markov chain Monte Carlo method
Elastic impedance inversion with high efficiency and high stability has become one of the main directions of seismic pre-stack inversion. The nonlinear elastic impedance inversion method based on a fast Markov...
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Open AccessLow level of swiprosin-1/EFhd2 in vestibular nuclei of spontaneously hypersensitive motion sickness mice
Susceptibility to motion sickness (MS) varies considerably among humans. However, the cause of such variation is unclear. Here, we used a classical genetic approach to obtain mouse strains highly sensitive and...
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The stabilized mixed finite element scheme of elasticity problem
In this paper, we consider a new mixed finite element scheme of the elasticity problem in two and three dimensions, and the new scheme can impose Neumann boundary condition directly. A new stabilized method is...
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Efficient quantum state transmission via perfect quantum network coding
Quantum network coding with the assistance of auxiliary resources can achieve perfect transmission of the quantum state. This paper suggests a novel perfect network coding scheme to efficiently solve the quantum
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Secure quantum network coding based on quantum homomorphic message authentication
As the principal security threat, pollution attacks also seriously affect the security of quantum network coding, just like they do for the classical network coding. Based on this, we first propose two secure ...
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Open AccessA phase 1, open-label study of LCAR-B38M, a chimeric antigen receptor T cell therapy directed against B cell maturation antigen, in patients with relapsed or refractory multiple myeloma
Chimeric antigen receptor (CAR) T cell therapy has demonstrated proven efficacy in some hematologic cancers. We evaluated the safety and efficacy of LCAR-B38M, a dual epitope-binding CAR T cell therapy directe...
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Open AccessThe sequence and de novo assembly of hog deer genome
Hog deer (Axis porcinus) is a small deer species in family Cervidae and has been undergoing a serious and global decline during the past decades. Chengdu Zoo currently holds a captive population of hog deer with ...
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Learning to select pseudo labels: a semi-supervised method for named entity recognition
Deep learning models have achieved state-of-the-art performance in named entity recognition (NER); the good performance, however, relies heavily on substantial amounts of labeled data. In some specific areas s...
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Open AccessSpinal CCL2 Promotes Pain Sensitization by Rapid Enhancement of NMDA-Induced Currents Through the ERK-GluN2B Pathway in Mouse Lamina II Neurons
Previous studies have shown that CCL2 (C–C motif chemokine ligand 2) induces chronic pain, but the exact mechanisms are still unknown. Here, we established models to explore the potential mechanisms. Behaviora...
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Tweety-Homolog 1 Facilitates Pain via Enhancement of Nociceptor Excitability and Spinal Synaptic Transmission
Tweety-homolog 1 (Ttyh1) is expressed in neural tissue and has been implicated in the generation of several brain diseases. However, its functional significance in pain processing is not understood. By disrupt...
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Quantum multi-proxy blind signature based on cluster state
Different from traditional digital signatures, quantum blind signatures can implement a signature without knowing the specific content, and their security is guaranteed by the basic principles of quantum mecha...
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Quantum Signature Scheme Based on Secret Sharing
Characterized by integrity and non-repudiation, digital signatures play an essential role in real life. Quantum digital signatures, which outperform classical types generally in safety, have been widely used i...
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Quantum sealed-bid auction protocol based on quantum secret sharing
A quantum sealed-bid auction (QSA) with post-confirmation can realize the public verification of the honesty of bidders. In this paper, we apply the quantum secret sharing (QSS) into the post-confirmation. Sur...
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GDH promotes isoprenaline-induced cardiac hypertrophy by activating mTOR signaling via elevation of α-ketoglutarate level
Numerous studies reveal that metabolism dysfunction contributes to the development of pathological cardiac hypertrophy. While the abnormal lipid and glucose utilization in cardiomyocytes responding to hypertro...
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Open AccessCRISPR FISHer enables high-sensitivity imaging of nonrepetitive DNA in living cells through phase separation-mediated signal amplification
The dynamic three-dimensional structures of chromatin and extrachromosomal DNA molecules regulate fundamental cellular processes and beyond. However, the visualization of specific DNA sequences in live cells, ...
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Open AccessCorrection: CRISPR FISHer enables high-sensitivity imaging of nonrepetitive DNA in living cells through phase separation-mediated signal amplification
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CircHIPK3 Regulates Vascular Smooth Muscle Cell Calcification Via the miR-106a-5p/MFN2 Axis
Atherosclerosis is the most common arterial disease and is closely related to vascular calcification. CircHIPK3 has been implicated in atherosclerosis development, but the possible downstream regulatory mechan...
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Asymmetric Circular Controlled Quantum State Transmission Scheme in Ideal and Noisy Environment
We present a four-participant scheme for the asymmetric circular controlled quantum states transmission. David is the controller, Alice, Bob and Charlie can complete the transmission of single-qubit, two-qubit...
