84 Result(s)
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Article
Xue** He
Life Sciences
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Article
Bacteriophage protein Dap1 regulates evasion of antiphage immunity and Pseudomonas aeruginosa virulence impacting phage therapy in mice
Bacteriophages have evolved diverse strategies to overcome host defence mechanisms and to redirect host metabolism to ensure successful propagation. Here we identify a phage protein named Dap1 from Pseudomonas ae...
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Life history of rotifers under temporally heterogeneous dietary sterol conditions
Herbivorous zooplankton potentially encounter temporal dietary heterogeneity in sterol, an essential group of lipids, over short or long time scales. There are a few studies showing that dietary sterol fluctua...
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Mediating role of root-exuded secondary metabolites in intraspecific interactions with Haloxylon ammodendron
Root exudates are pivotal in soil carbon and nutrient cycling, enhancing nutrient availability and plant resource utilization efficiency under stress. Despite challenges in obtaining accurate soil-borne signal...
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HSP70 protects PC12 cells against TBHP-induced apoptosis and oxidative stress by activating the Nrf2/HO-1 signaling pathway
HSP70 exhibits neuroprotective, antioxidant, and anti-apoptotic properties, which are crucial in preventing spinal cord injury (SCI) induced by oxidative stress and apoptosis. In this study, we assessed the po...
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Open AccessCellular communication network factor 1 promotes retinal leakage in diabetic retinopathy via inducing neutrophil stasis and neutrophil extracellular traps extrusion
Diabetic retinopathy (DR) is a major cause of blindness and is characterized by dysfunction of the retinal microvasculature. Neutrophil stasis, resulting in retinal inflammation and the occlusion of retinal mi...
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Correction to: Changing regularity of plant and insect community characteristics due to pest outbreaks in Larix principis‑rupprechtii plantations
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Open AccessIdentification and validation of stable reference genes for RT-qPCR analyses of Kobresia littledalei seedlings
Kobreisa littledalei, belonging to the Cyperaceae family is the first Kobresia species with a reference genome and the most dominant species in Qinghai-Tibet Plateau alpine meadows. It has several resistance gen...
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Changing regularity of plant and insect community characteristics due to pest outbreaks in Larix principis-rupprechtii plantations
Research has indicated that simple forest ecosystem composition, structure and diversity have uncomplicated community relationships and insufficient pest control capabilities. To investigate changing character...
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Open AccessEffects of nitrate- and ammonium- nitrogen on anatomical and physiological responses of Catalpa bungei under full and partial root-zone drought
Catalpa bungei is a precious timber species distributed in North China where drought often occurs. To clarify adaptive responses of C. bungei to partial- and full- root-zone drought under the influence of nitroge...
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The oral microbiome: diversity, biogeography and human health
The human oral microbiota is highly diverse and has a complex ecology, comprising bacteria, microeukaryotes, archaea and viruses. These communities have elaborate and highly structured biogeography that shapes...
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Identifying keystone species in microbial communities using deep learning
Previous studies suggested that microbial communities can harbour keystone species whose removal can cause a dramatic shift in microbiome structure and functioning. Yet, an efficient method to systematically i...
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HRD1 reduction promotes cholesterol-induced vascular smooth muscle cell phenotypic change via endoplasmic reticulum stress
Phenotypic change of vascular smooth muscle cells (VSMCs) is the main contributor of vascular pathological remodeling in atherosclerosis. The endoplasmic reticulum (ER) is critical for maintaining VSMC functio...
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Effects of submergence stress on germination and seedling growth of direct-seeded rice and evaluation of submergence tolerance
Direct-seeded rice is often affected by water accumulation caused by uneven soil preparation in the field after sowing and is vulnerable to flooding. Thus, it is important to select submergence-tolerant rice v...
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Open AccessCSE reduces OTUD4 triggering lung epithelial cell apoptosis via PAI-1 degradation
Ovarian tumor family deubiquitinase 4 (OTUD4), a member of the OTU deubiquitinating enzyme, is implicated to decrease in cancer to regulate cell apoptosis. However, the role of OTUD4 in cigarette smoke induced...
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Open AccessLocal transplantation of mesenchymal stem cells improves encephalo-myo-synangiosis-mediated collateral neovascularization in chronic brain ischemia
To explore whether local transplantation of mesenchymal stem cells (MSCs) in temporal muscle can promote collateral angiogenesis and to analyze its main mechanisms of promoting angiogenesis.
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Open AccessCRISPR screen identifies the role of RBBP8 in mediating unfolded protein response induced liver damage through regulating protein synthesis
Unfolded protein response (UPR) maintains the endoplasmic reticulum (ER) homeostasis, survival, and physiological function of mammalian cells. However, how cells adapt to ER stress under physiological or disea...
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Open AccessGalectin-1-dependent ceRNA network in HRMECs revealed its association with retinal neovascularization
Retinal neovascularization (RNV) is a leading cause of blindness worldwide. Long non-coding RNA (lncRNA) and competing endogenous RNA (ceRNA) regulatory networks play vital roles in angiogenesis. The RNA-bindi...
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The Influence of Nitrogen (N) Input on the Sink–Source Relationship of ‘Korla Fragrant’ Pear (Pyrus brestschneideri Rehd.Cv.)
This study investigated the influence of nitrogen (N) input on the characteristics of the sink–source relationship of ‘Korla Fragrant’ pear tree to analyze how N levels regulate the sink–source relationship an...
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Photoperiod controls plant seed size in a CONSTANS-dependent manner
Photoperiodic plants perceive changes in day length as seasonal cues to orchestrate their vegetative and reproductive growth. Although it is known that the floral transition of photoperiod-sensitive plants is ...
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Open AccessMFG-E8 stabilized by deubiquitinase USP14 suppresses cigarette smoke-induced ferroptosis in bronchial epithelial cells
Milk fat globule epidermal growth factor 8 (MFG-E8) participates in a range of cellular processes, including reducing apoptosis and oxidative stress. However, its protective activity against cigarette smoke-in...
