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  1. No Access

    Article

    Tumor gangliosides accelerate murine tumor angiogenesis

    Tumor cells shed gangliosides and populate their microenvironment with these biologically active membrane glycosphingolipids. In vitro, ganglioside enrichment amplifies receptor tyrosine kinase signaling and a...

    Yihui Liu, Assefa Wondimu, Su Yan, Daniel Bobb, Stephan Ladisch in Angiogenesis (2014)

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    Article

    Induction of GM1a/GD1b synthase triggers complex ganglioside expression and alters neuroblastoma cell behavior; a new tumor cell model of ganglioside function

    Neuroblastoma is the most common extracranial solid tumor in children and tumor ganglioside composition has been linked to its biological and clinical behavior. We recently found that high expression of comple...

    Lixian Dong, Yihui Liu, Anamaris M. Colberg-Poley, Karen Kaucic in Glycoconjugate Journal (2011)

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    Article

    Structural characterization andin vivo immunosuppressive activity of neuroblastoma GD2

    Shedding of neuroblastoma gangliosides is positively correlated with tumour progression in patients with neuroblastoma. In assessing the biological activity of these ganglioside molecules, we recently found th...

    Ruixiang Li, Douglas Gage, Robert Mckallip, Stephan Ladisch in Glycoconjugate Journal (1996)

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    Article

    VP-16 and the treatment of histiocytosis

    Helmut Gadner, Stephan Ladisch, Maurizio Aricó in European Journal of Pediatrics (1994)

  5. Article

    Hepatic Ganglioside Abnormalities in a Patient with Familial Erythrophagocytic Lymphohistiocytosis

    Summary: Familial erythrophagocytic lymphohistiocytosis (FEL) is an autosomal recessive disease of unknown pathogenesis. Because of evidence of increased circulating and hepatic lipids in FEL, we performed a c...

    Clifford G Wong, Stephan Ladisch, Charles C Sweeley in Pediatric Research (1983)

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    Article

    Plasma inhibition of lymphocyte proliferation in nephrotic syndrome: Correlation with hyperlipidemia

    Plasma-mediated inhibition of normal lymphoproliferation is an unexplained immunologic abnormality frequently observed in nephrotic syndrome. Since hyperlipidemia, also common in nephrotic syndrome, has been l...

    Carl Lenarsky, Stanley C. Jordan, Stephan Ladisch in Journal of Clinical Immunology (1982)

  7. Article

    941 PLASMA INHIBITION OF LYMPHOCYTE BLASTOGENESIS IN NEPHROTIC SYNDROME: CORRELATION WITH HYPERLIPIDEMIA

    The plasma of patients with Nephrotic Syndrome suppresses in vitro lymphocyte blastogenesis, but the mechanism of this effect has not been defined. The frequent association of Nephrotic Syndrome with hypertriglyc...

    Carl Lenarsky, Stanley Jordan, Stephan Ladisch, Stephen A Feig in Pediatric Research (1981)

  8. Article

    IMMUNODEFICIENCY IN LYMPHOHISTIOCYTOSIS: DEFECTIVE CELLULAR IMMUNITY IN ASSOCIATION WITH HYPERLIPIDEMIA

    Lymphohistiocytosis (LH) is a familial syndrome characterized by abnormal accumulation of non-malignant histiocytes in lymph nodes, liver, and spleen, erythrophagocytosis, hepatoaplenomegaly, recurrent fever, ...

    Stephan Ladisch, David G Poplack, Betty J Holiman, R Michael Blaese in Pediatric Research (1977)