202 Result(s)
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Shu-Yuan **ao
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One-step pore diffusion mechanism of Li+ in solid electrolyte interphase for fast-charging lithium-ion battery
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Open AccessAugmented microglial endoplasmic reticulum-mitochondria contacts mediate depression-like behavior in mice induced by chronic social defeat stress
Extracellular ATP (eATP) signaling through the P2X7 receptor pathway is widely believed to trigger NLRP3 inflammasome assembly in microglia, potentially contributing to depression. However, the cellular stress...
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Open AccessTrends in maternal and child health in China and its urban and rural areas from 1991 to 2020: a joinpoint regression model
The long-term trends in maternal and child health (MCH) in China and the national-level factors that may be associated with these changes have been poorly explored. This study aimed to assess trends in MCH ind...
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Open AccessEarly onset and liver failure indicating poor prognosis of infant liver failure syndrome type 1
Infantile liver failure syndrome type 1 (ILFS1, OMIM #615,438), caused by leucyl-tRNA synthase 1 (LARS1, OMIM *151,350) deficiency, is a rare autosomal-recessive disorder. The clinical manifestations, molecular-g...
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Discovery of a selective TRF2 inhibitor FKB04 induced telomere shortening and senescence in liver cancer cells
Telomere repeat binding factor 2 (TRF2), a critical element of the shelterin complex, plays a vital role in the maintenance of genome integrity. TRF2 overexpression is found in a wide range of malignant cancer...
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Open AccessCardiomyocyte-specific overexpression of GPR22 ameliorates cardiac injury in mice with acute myocardial infarction
The activation of G protein-coupled receptors (GPCR) signaling by external stimuli has been implicated in inducing cardiac stress and stress responses. GPR22 is an orphan GPCR expressed in brains and hearts, w...
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Advance in reversible Zn anodes promoted by 2D materials
With the growing energy demand associated with high safety and low-cost requirement, aqueous zinc-ion batteries (AZIBs) have been considered as one of the most promising next-generation batteries. However, som...
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Six Phthalides as Potent Modulators of the Blood Tumor Barrier Increase the Transmembrane Transport of Compatible Compounds Via Transcellular and Paracellular Pathways
The treatment of brain tumors is greatly limited due to the presence of the blood tumor barrier (BTB). Our previous research has shown that the essential oil of chuanxiong promoted temozolomide entry into glio...
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Numerical simulations for radon migration and exhalation behavior during measuring radon exhalation rate with closed-loop method
Accurate measurements of the radon exhalation rate help identify and evaluate radon risk regions in the environment. Among these measurement methods, the closed-loop method is frequently used. However, traditi...
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Human Odour Attracts Anopheles and Culex Mosquitoes only Upon Sweating
Mosquitoes transmit many pathogens, like malaria (by Anopheles), lymphatic filariasis (by Culex), Zika virus and Dengue virus (by Aedes). Female mosquitoes have robust preferences for human odours over animal odo...
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Open AccessID1 expressing macrophages support cancer cell stemness and limit CD8+ T cell infiltration in colorectal cancer
Elimination of cancer stem cells (CSCs) and reinvigoration of antitumor immunity remain unmet challenges for cancer therapy. Tumor-associated macrophages (TAMs) constitute the prominant population of immune ce...
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Open AccessAxion-assisted resonance oscillation rescues the Dodelson–Widrow mechanism
The \(\textrm{keV}\) keV scale sterile neutrino was a qualified candidate f...
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Comparative Perspective of Evolution of SARS-CoV-2 and 1918 Influenza Virus
Omicron variants of SARS-CoV-2 virus have higher infectivity, more immune escape but lower risk of severe clinical outcomes than the ancestral variants. However, people are still wondering whether SARS-CoV-2 m...
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Pregnane X receptor activation alleviates renal fibrosis in mice via interacting with p53 and inhibiting the Wnt7a/β-catenin signaling
Renal fibrosis is a common pathological feature of chronic kidney disease (CKD) with various etiologies, which seriously affects the structure and function of the kidney. Pregnane X receptor (PXR) is a member ...
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Isolation and characterization of an endophytic fungi from Zingiber officinale Rosc. and its activity to promote the growth of tissue culture ginger plantlets in bottles
Zingiber Officinale is a perennial rhizomatous vegetable and seasonings with amazing flavor, as well as a wide range of pharmacological activity. Endophytic fungi live within plants, and some of them can help pla...
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Correlation between burst suppression and postoperative delirium in elderly patients: a prospective study
To explore the correlation between intraoperative burst suppression (BS) and postoperative delirium (POD) in elderly patients, and provide more ideas for reducing POD in clinical.
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Carrier burden of over 300 diseases in Han Chinese identified by expanded carrier testing of 300 couples using assisted reproductive technology
Expanded carrier screening (ECS) has become a common practice for identifying carriers of monogenic diseases. However, existing large gene panels are not well-tailored to Chinese populations. In this study, EC...
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The power of employee exchange belief: How psychological contract strength mediates the relationship of HR practice consistency and organizational commitment
This study examines the concept of the psychological contract strength deriving from an employee’s expectation of mutual exchange with regard to their employers’ obligation fulfillment. This study explores the...
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Open AccessFertilization-induced reactive nitrogen gases and carbon dioxide emissions: insight to the carbon-nitrogen cycles
Different agricultural practices can pose significant threats to environmental quality and human health. This study aimed to assess the emissions of reactive nitrogen (NH3, NOx, and N2O) and carbon dioxide (CO2) ...
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Intrusion Detection Method Based on Denoising Diffusion Probabilistic Models for UAV Networks
Security is important for UAV networks because of the need for a cyber-secure flying air space for UAV group communication to complete the complex tasks cooperatively. Network intrusion detection is an effecti...
