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  1. Article

    Open Access

    Red blood cell distribution width is associated with sarcopenia risk in early-stage non-small cell lung cancer

    Sarcopenia has received increasing attention in non-small cell lung cancer (NSCLC). Red blood cell distribution width (RDW) is a significant component of the complete blood count and indicates the heterogeneit...

    Qing-chun Jia, Ling Qin, Ye Niu, Le Liu, **-** Liu, Shi-di Miao in BMC Cancer (2024)

  2. Article

    Open Access

    Association between c-type lectin-like receptor 2 and microsatellite instability in colorectal cancer: a cross-sectional study

    As a transmembrane protein, C-type lectin-like receptor 2 (CLEC-2) is mainly expressed on platelets and released into plasma after platelet activation. Activated platelets participate in the regulation of inna...

    **n Zhang, Jia-rui Yuan, **n Wang, Shuang Fu, Rui-tao Wang, Guang-yu Wang in BMC Cancer (2022)

  3. Article

    Open Access

    Preoperative PDW levels predict pulmonary metastasis in patients with hepatocellular carcinoma

    In hepatocellular carcinoma (HCC), pulmonary metastasis (PM) after hepatectomy is associated with poor clinical outcomes. The crucial phases of tumour cell proliferation, angiogenesis, and metastasis all entai...

    Wen-juan Huang, Guang-yu Wang, Zeng-yao Liu, Meng-lin Zhang, Wen Wang in BMC Cancer (2022)

  4. Article

    Open Access

    Utility of mean platelet volume in differentiating intrahepatic cholangiocarcinoma from hepatocellular carcinoma

    Intrahepatic cholangiocarcinoma (ICC) and hepatocellular carcinoma (HCC) are the most prevalent histologic types of primary liver cancer. HCC and ICC differ in treatment and prognosis, warranting an effective ...

    **n Zhang, Wen-Juan Huang, Meng-Lin Zhang, Wen Wang, Ye Niu in BMC Gastroenterology (2022)

  5. Article

    Open Access

    Association between apoptosis inhibitor of macrophage and microsatellite instability status in colorectal cancer

    The microsatellite instability (MSI) in colorectal cancer (CRC) has a more favorable clinical outcome and is characterized by highly upregulated expression of various immunological checkpoints than microsatell...

    Wen-juan Huang, **n Wang, Meng-lin Zhang, Li Li, Rui-tao Wang in BMC Gastroenterology (2020)

  6. Article

    Open Access

    Reduced mean platelet volume levels predict shorter survival in patients with resectable pancreatic ductal adenocarcinoma and type 2 diabetes

    Type 2 diabetes mellitus (T2DM) increased the risk of develo** pancreatic cancer. Pancreatic ductal adenocarcinoma (PDAC) is the most common neoplastic disease originating from the pancreas. Increasing evide...

    Ji-bin Yin, Na Li, Ming-ming Cui, **n Wang, Rui-tao Wang in BMC Gastroenterology (2020)

  7. No Access

    Article

    Preoperative mean platelet volume predicts survival in breast cancer patients with type 2 diabetes

    Patients with type 2 diabetes mellitus (T2DM) have an increased risk of breast cancer (BC). Furthermore, growing evidence suggests that activated platelets play a crucial role in tumor and T2DM. Mean platelet ...

    Na Li, **n-hai Lv, **n Wang, Rui-tao Wang, Yuan-xi Huang in Breast Cancer (2019)

  8. Article

    Open Access

    Mean platelet volume predicts survival in pancreatic cancer patients with synchronous liver metastases

    Most pancreatic cancer (PC) patients manifest multiple liver metastases at the time of diagnosis. Activated platelets play a key role in tumor growth and tumor metastases. Mean platelet volume (MPV) is a plate...

    Ji-bin Yin, **n Wang, **n Zhang, Li Liu, Rui-tao Wang in Scientific Reports (2018)

  9. No Access

    Article

    Association of decreased mean platelet volume with renal cell carcinoma

    Renal cell carcinoma (RCC) is the third most common genitourinary cancer. Activated platelets play a pivotal role in cancer development and progression. Altered mean platelet volume (MPV) has been reported in ...

    Zhi-yuan Yun, **n Zhang, Zhi-** Liu in International Journal of Clinical Oncology (2017)

  10. Article

    Open Access

    Elevated mean platelet volume predicts poor prognosis in colorectal cancer

    Altered mean platelet volume (MPV) is implicated in several malignancies. However, the clinicopathological significance and prognostic value of MPV in colorectal cancer (CRC) is still elusive. The purpose of t...

    Na Li, Zhiwei Yu, **n Zhang, Tiemin Liu, Yu-xiang Sun, Rui-tao Wang in Scientific Reports (2017)

  11. Article

    Open Access

    Lower mean platelet volume predicts poor prognosis in renal cell carcinoma

    Altered mean platelet volume (MPV) is found in several malignancies. Remarkably, there is little consensus on using the value of MPV in the prognostic evaluations of renal cell carcinoma (RCC). The aim of this...

    Zhi-yuan Yun, **n Zhang, Yan-song Liu, Tiemin Liu, Zhi-** Liu in Scientific Reports (2017)

  12. Article

    Open Access

    Platelet distribution width correlates with prognosis of non-small cell lung cancer

    Platelets play a multifaceted role in cancer progression and metastasis. Mean platelet volume (MPV) and platelet distribution width (PDW) are commonly used platelet parameters from routine blood test. The aim ...

    Ming-ming Cui, Na Li, **ng Liu, Zhi-yuan Yun, Ye Niu, Yong Zhang in Scientific Reports (2017)

  13. Article

    Open Access

    Increased platelet distribution width predicts poor prognosis in melanoma patients

    Activated platelets promote cancer progression and metastasis. Nevertheless, the prognostic value of platelet indices in melanoma had been rarely reported. The aim of this study was to investigate the predicti...

    Na Li, Zhiyong Diao, **aoyi Huang, Ye Niu, Tiemin Liu, Zhi-** Liu in Scientific Reports (2017)

  14. Article

    Gallstone disease is associated with arterial stiffness progression

    Gallstones have been linked to dyslipidemia, metabolic syndrome and cardiovascular disease. Arterial stiffness is an indicator of subclinical atherosclerosis. The aim of this study was to prospectively examine...

    Kai-**g Yu, Ji-rong Zhang, Ying Li, **aoyi Huang, Tiemin Liu in Hypertension Research (2017)

  15. No Access

    Article

    Association between whole blood viscosity and arterial stiffness in patients with type 2 diabetes mellitus

    Type 2 diabetes mellitus (DM) carries an increased risk for cardiovascular complications. The brachial-ankle pulse wave velocity (baPWV) is an index for early atherosclerotic changes. Recently, the effect of ...

    Ying Li, **u-xia Tian, Tiemin Liu, Rui-tao Wang in Endocrine (2015)

  16. No Access

    Article

    Mean platelet volume is negatively associated with bone mineral density in postmenopausal women

    Osteoporosis (OP) has been associated with cardiovascular disease. More specifically, osteoporosis was found to be an independent predictor of cardiovascular mortality. Recent studies revealed that platelets p...

    Xue-song Li, Ji-rong Zhang, Song-yan Meng in Journal of Bone and Mineral Metabolism (2012)

  17. Article

    Open Access

    A rare giant gastrointestinal stromal tumor of the stomach traversing the upper abdomen: a case report and literature review

    We present the case of a 66-year-old woman with a huge gastrointestinal stromal tumor of the stomach that traversed her upper abdomen. The predominant abdominal sign was a huge, palpable mass, but there were n...

    Lei Zhou, Chang Liu, Ji-Gang Bai, Ji-Chao Wei, Kai Qu in World Journal of Surgical Oncology (2012)

  18. Article

    Knockdown of FoxM1 by siRNA interference decreases cell proliferation, induces cell cycle arrest and inhibits cell invasion in MHCC-97H cells in vitro

    To investigate the effects of small interfering RNA (siRNA) knockdown of forkhead box M1 (FoxM1) on the proliferation and invasion capacities of human hepatocellular carcinoma MHCC-97H cells in vitro.

    Qi-fei Wu, Chang Liu, Ming-hui Tai, Dong Liu, Lei Lei in Acta Pharmacologica Sinica (2010)