5 Result(s)
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Article
Rossella Alfano
Medicine & Public Health
Medicine/Public Health, general
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Article
Exploring mitochondrial heteroplasmy in neonates: implications for growth patterns and overweight in the first years of life
Mitochondrial heteroplasmy reflects genetic diversity within individuals due to the presence of varying mitochondrial DNA (mtDNA) sequences, possibly affecting mitochondrial function and energy production in c...
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Article
Open AccessMaternal educational attainment in pregnancy and epigenome-wide DNA methylation changes in the offspring from birth until adolescence
Maternal educational attainment (MEA) shapes offspring health through multiple potential pathways. Differential DNA methylation may provide a mechanistic understanding of these long-term associations. We aimed...
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Article
Open AccessCord blood epigenome-wide meta-analysis in six European-based child cohorts identifies signatures linked to rapid weight growth
Rapid postnatal growth may result from exposure in utero or early life to adverse conditions and has been associated with diseases later in life and, in particular, with childhood obesity. DNA methylation, interf...
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Article
Open AccessCord blood metabolites and rapid postnatal growth as multiple mediators in the prenatal propensity to childhood overweight
The mechanisms underlying childhood overweight and obesity are poorly known. Here, we investigated the direct and indirect effects of different prenatal exposures on offspring rapid postnatal growth and overwe...
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Article
Open AccessCord blood metabolic signatures predictive of childhood overweight and rapid growth
Metabolomics may identify biological pathways predisposing children to the risk of overweight and obesity. In this study, we have investigated the cord blood metabolic signatures of rapid growth in infancy and...
