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    Article

    Exploring mitochondrial heteroplasmy in neonates: implications for growth patterns and overweight in the first years of life

    Mitochondrial heteroplasmy reflects genetic diversity within individuals due to the presence of varying mitochondrial DNA (mtDNA) sequences, possibly affecting mitochondrial function and energy production in c...

    Charlotte Cosemans, Rossella Alfano, Hanne Sleurs in International Journal of Obesity (2024)

  2. Article

    Open Access

    The association between newborn cord blood steroids and ambient prenatal exposure to air pollution: findings from the ENVIRONAGE birth cohort

    Knowledge of whether prenatal exposure to ambient air pollution disrupts steroidogenesis is currently lacking. We investigated the association between prenatal ambient air pollution and highly accurate measure...

    Michelle Plusquin, Congrong Wang, Charlotte Cosemans in Environmental Health (2023)

  3. Article

    Open Access

    In utero particulate matter exposure in association with newborn mitochondrial ND4L10550A>G heteroplasmy and its role in overweight during early childhood

    Mitochondria play an important role in the energy metabolism and are susceptible to environmental pollution. Prenatal air pollution exposure has been linked with childhood obesity. Placental mtDNA mutations ha...

    Charlotte Cosemans, Congrong Wang, Rossella Alfano in Environmental Health (2022)

  4. Article

    Open Access

    Lower iodine storage in the placenta is associated with gestational diabetes mellitus

    The micronutrient iodine is essential for a healthy intrauterine environment and is required for optimal fetal growth and neurodevelopment. Evidence linking urinary iodine concentrations, which mainly reflects...

    Kristof Y. Neven, Bianca Cox, Charlotte Cosemans, Wilfried Gyselaers in BMC Medicine (2021)

  5. Article

    Open Access

    Breastfeeding predicts blood mitochondrial DNA content in adolescents

    Nutrition during early childhood is linked to metabolic programming. We hypothesized that breastfeeding has long-term consequences on the energy metabolism exemplified by mitochondrial DNA (mtDNA). As part of ...

    Charlotte Cosemans, Tim S. Nawrot, Bram G. Janssen, Annette Vriens in Scientific Reports (2020)