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108 Result(s)
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Article
Closed-Form Solutions for a Circular Tunnel in Elastic-Brittle-Plastic Ground with the Original and Generalized Hoek–Brown Failure Criteria
The paper presents a closed-form solution for the convergence curve of a circular tunnel in an elasto-brittle-plastic rock mass with both the Hoek–Brown and generalized Hoek–Brown failure criteria, and a linea...
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Article
Open AccessSoil-transmitted helminth infections and physical fitness in school-aged Bulang children in southwest China: results from a cross-sectional survey
Chronic soil-transmitted helminth (STH) infections have been associated with reduced physical fitness, but available evidence is limited. The aim of this cross-sectional survey was to assess the feasibility of...
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Article
Thermal conductivity of tunable lamellar aluminum oxide/polymethyl methacrylate hybrid composites
We prepared hybrid aluminum oxide (Al2O3)/polymethyl methacrylate (PMMA) composites with tunable lamellae, produced through a two-step synthetic method: fabrication of inorganic scaffolds via ice-templating, foll...
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Synthesis of three-dimensional agaric-like biomorphic TiO2 by a facile method with Coscinodiscus sp. frustule
The paper aims to expand the application of natural marine algae. Marine diatoms, which have intricate frustule structures, can serve as bio-template for preparing three-dimensional materials. A simple and eff...
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Research on the critical conditions for clay particle release during saline aquifer freshening process
Water sensitivity phenomenon occurs during saline aquifer freshening process in seawater intrusion area, and clay particles released in the phenomenon can damage the infiltration capacity of the aquifer. In or...
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Article
Deformation temperature and lamellar thickness dependency of Form I to Form III phase transition in syndiotactic polypropylene during tensile stretching
Phase transition from form I to form III in syndiotactic polypropylene crystallized at different conditions during tensile deformation at different temperatures was investigated by using in situ synchrotron wide ...
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Article
Promotion of expression of interferon-stimulated genes in U937 monocytic cells by HIV RNAs, measured using stable isotope labeling with amino acids in cell culture (SILAC)
Type I interferon (IFN) exerts strong antiviral activity, particularly against human immunodeficiency virus (HIV), and although several viral proteins have been shown to deregulate IFN induction, little is kno...
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Article
Ultraviolet nano-photodetector based on ZnS:Cl nanoribbon/Au Schottky junctions
We report on a semiconductor nanostructures/metal Schottky junction for optoelectronic device application. The n-type ZnS nanoribbons (NRs) with an electron mobility of 64.9 cm V−1 s−1 and electron concentration ...
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Article
Swine PPAR-γ2 expression upregulated in skeletal muscle of transgenic mice via the swine Myozenin-1 gene promoter
Myozenin-1 (Myoz1) gene-encoded calsarcin-2 protein was expressed exclusively in fast-twitch muscles. Peroxisome proliferator-activated receptor γ2 (PPAR-γ2) is a key regulator of adipocyte diffe...
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Article
Open AccessThe Chinese herb-derived Sparstolonin B suppresses HIV-1 transcription
The Chines herb derived Sparstolonin B, (SsnB), is a recently identified natural compound that selectively blocks TLR2- and TLR4-mediated inflammatory signaling. But it is unknown whether this compound has any...
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Article
MicroRNAs regulate the immunometabolic response to viral infection in the liver
25-Hydroxycholesterol induces expression of the microRNAs miR-130b and miR-185 in HCV-infected cells, and these inhibit viral fatty acid desaturation, lipid uptake and biosynthesis, thereby limiting infection....
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Article
Open AccessExpression, purification and biological characterization of the extracellular domain of CD40 from Pichia pastoris
CD40, also called Bp50, is a novel member of the TNF receptor superfamily. Based on its important role in multiple physiological and pathological processes, the CD40 signaling pathway has become a vital target...
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Article
Open AccessBias-polarity-dependent resistance switching in W/SiO2/Pt and W/SiO2/Si/Pt structures
SiO2 is the most significantly used insulator layer in semiconductor devices. Its functionality was recently extended to resistance switching random access memory, where the defective SiO2 played an active role a...
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Article
A deblurring procedure for two-dimensional small angle X-ray scattering patterns
A general pre-processing procedure of the measured SAXS patterns for reducing the effect of beam stop and beam stop holder is described. A proper method for automatically choosing the regularization parameter ...
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Article
Evolution of the microbial community of the biofilm in a methane-based membrane biofilm reactor reducing multiple electron acceptors
Previous work documented complete perchlorate reduction in a membrane biofilm reactor (MBfR) using methane as the sole electron donor and carbon source. This work explores how the biofilm’s microbial community...
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Article
Open AccessmiR-144 and targets, c-fos and cyclooxygenase-2 (COX2), modulate synthesis of PGE2 in the amnion during pregnancy and labor
Labor is initiated as a result of hormonal changes that are induced by the activation of the inflammatory response and a series of biochemical events. The amnion, which is the primary source of prostaglandin E...
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Article
Open AccessInfluenza B virus non-structural protein 1 counteracts ISG15 antiviral activity by sequestering ISGylated viral proteins
The ubiquitin-like protein ISG15 and its conjugation to proteins (ISGylation) are strongly induced by type I interferon. Influenza B virus encodes non-structural protein 1 (NS1B) that binds human ISG15 and pro...
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Article
Open AccessCrystal structures of the bifunctional tRNA methyltransferase Trm5a
tRNA methyltransferase Trm5 catalyses the transfer of a methyl group from S-adenosyl-L-methionine to G37 in eukaryotes and archaea. The N1-methylated guanosine is the product of the initial step of the wyosine...
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Article
Open AccessBcl-3 regulates TGFβ signaling by stabilizing Smad3 during breast cancer pulmonary metastasis
Transforming growth factor beta (TGFβ) signaling in breast cancer is selectively associated with pulmonary metastasis. However, the underlying mechanisms remain unclear. Here we show that Bcl-3, a member of the I...
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Study on dye-loading mode on TiO2 films and impact of co-sensitizers on highly efficient co-sensitized solar cells
Two organic dyes (T-C0 and D-0) with different molecular size were employed as co-sensitizers to investigate co-sensitized solar cells (AZ260/T-C0 and AZ260/D-0). Their match of molecular size, light absorption, ...