27,050 Result(s)

Article

NF-κB inhibitor alpha controls SARS-CoV-2 infection in ACE2-overexpressing human airway organoids

As SARS-CoV-2 continues to spread worldwide, tractable primary airway cell models that recapitulate the cell-intrinsic response to arising viral variants are needed. Here we describe an adult stem cell-derived...

Camille R. Simoneau, Pei-Yi Chen, Galen K. **ng, Jennifer M. Hayashi… in Scientific Reports (2024)

Article

Influence of thickness and strength on plastic instability in tailored steel structures

A mathematical model was intricately devised to explore the influence of continuous variations in thickness and mechanical properties on the performance of tailor rolled blanks (TRB) and tailor rolled tubes (T...

Rihuan Lu, Shoudong Chen, **aogong Wang, Meihui Li, Sijia Zhang… in Scientific Reports (2024)

Article

Designed wrinkles for optical encryption and flexible integrated circuit carrier board

Patterns on polymers usually have different mechanical properties as those of the substrates, causing deformation or distortion and even detachment of the patterns from the polymer substrates. Herein, we prese...

Shilong Zhong, Zhaoxiang Zhu, Qizheng Huo, Yubo Long, Li Gong… in Nature Communications (2024)

Article

A novel technique for the single-port laparoscopic percutaneous extraperitoneal closure (SLPEC) of paediatric isolated giant inguinal hernias using double-modified hernia needles

The objective was to explore the efficacy of single-port laparoscopic percutaneous extraperitoneal closure using double-modified hernia needles with hydrodissection (SLPEC group) and two-port laparoscopic perc...

Long-Yao Xu, Xu Cui, Wen-Hua Huang, Liu Chen, Chao-Ming Zhou in Scientific Reports (2024)

Article

Study on methane degradation by microbial agents based on chelating wetting agent carriers

Due to the low permeability characteristics of the deep gas-containing coal seam, the conventional prevention and control measures that cannot solve the problems of gas outbursts are unsatisfactory for the pre...

Yumiao Han, Lianman Xu, Runjie Zhang, ** Lv, Fengshuo Yang, Chen Ma in Scientific Reports (2024)

Article

Reducing nonradiative recombination for highly efficient inverted perovskite solar cells via a synergistic bimolecular interface

Reducing interface nonradiative recombination is important for realizing highly efficient perovskite solar cells. In this work, we develop a synergistic bimolecular interlayer (SBI) strategy via 4-methoxypheny...

Shaobing **ong, Fuyu Tian, Feng Wang, Ai** Cao, Zeng Chen… in Nature Communications (2024)

Article

Capillary compression induced outstanding n-type thermoelectric power factor in CNT films towards intelligent temperature controller

One-dimensional carbon nanotubes are promising candidates for thermoelectrics because of their excellent electrical and mechanical properties. However, the large n-type power factor remains elusive in macrosco...

Hong Wang, Kuncai Li, **n Hao, Jiahao Pan, Tiantian Zhuang, Xu Dai… in Nature Communications (2024)

Article

Effects of low-intensity pulsed ultrasound on the microorganisms of expressed prostatic secretion in patients with IIIB prostatitis

To detect and analyze the changes of microorganisms in expressed prostatic secretion (EPS) of patients with IIIB prostatitis before and after low-intensity pulsed ultrasound (LIPUS) treatment, and to explore t...

Wei-Jie Song, Ji-Wei Huang, Yuan Liu, Jie Wang, Wei Ding… in Scientific Reports (2024)

Article

Clotrimazole inhibits growth of multiple myeloma cells in vitro via G0/G1 arrest and mitochondrial apoptosis

Patients with multiple myeloma (MM) experience relapse and drug resistance; therefore, novel treatments are essential. Clotrimazole (CTZ) is a wide-spectrum antifungal drug with antitumor activity. However, CT...

Yang Song, Hui Zhang, Jie Geng, Haoran Chen, Yang Bo, Xuechun Lu in Scientific Reports (2024)

Article

A single-cell transcriptomic study of heterogeneity in human embryonic tanycytes

Disruptions in energy homeostasis can lead to diseases like obesity and diabetes, affecting millions of people each year. Tanycytes, the adult stem cells in the hypothalamus, play crucial roles in assisting hy...

Yiguang Bai, Qiaoling Chen, Yuan Li in Scientific Reports (2024)

Article

NLRC5 promotes tumorigenesis by regulating the PI3K/AKT signaling pathway in cervical cancer

Cervical cancer (CC) is the fourth most common cancer among women worldwide. NLR Family CARD Domain Containing 5 (NLRC5) plays an important role in tumorigenesis. However, its effect and mechanism in CC remain...

Lin Ling, Jiahua Chen, Lei Zhan, Juanjuan Fu, Runhua He, Wenyan Wang… in Scientific Reports (2024)

Article

Social coevolution and Sine chaotic opposition learning Chimp Optimization Algorithm for feature selection

Feature selection is a hot problem in machine learning. Swarm intelligence algorithms play an essential role in feature selection due to their excellent optimisation ability. The Chimp Optimisation Algorithm (...

Li Zhang, **aoBo Chen in Scientific Reports (2024)

Article

NBS1 lactylation is required for efficient DNA repair and chemotherapy resistance

The Warburg effect is a hallmark of cancer that refers to the preference of cancer cells to metabolize glucose anaerobically rather than aerobically^1,2. This results in substantial accumulation of lacate, the end...

Hengxing Chen, Yun Li, Huafu Li, **ancong Chen, Huafeng Fu, Deli Mao, Wei Chen… in Nature (2024)

Article

KAT8-mediated H4K16ac is essential for sustaining trophoblast self-renewal and proliferation via regulating CDX2

Abnormal trophoblast self-renewal and differentiation during early gestation is the major cause of miscarriage, yet the underlying regulatory mechanisms remain elusive. Here, we show that trophoblast specific ...

Shilei Bi, Lijun Huang, Yongjie Chen, Zhenhua Hu, Shanze Li… in Nature Communications (2024)

Article

Author Correction: ALKBH5-mediated m6A modification of IL-11 drives macrophage-to-myofibroblast transition and pathological cardiac fibrosis in mice

Tao Zhuang, Mei-Hua Chen, Ruo-** Wu, **g Wang, **-De Hu… in Nature Communications (2024)

Article

Middle and Late Pleistocene Denisovan subsistence at Baishiya Karst Cave

Genetic and fragmented palaeoanthropological data suggest that Denisovans were once widely distributed across eastern Eurasia^1–3. Despite limited archaeological evidence, this indicates that Denisovans were capab...

Huan **a, Dongju Zhang, Jian Wang, Zandra Fagernäs, Ting Li, Yuanxin Li… in Nature (2024)

Article

Effect of silicon spraying on rice photosynthesis and antioxidant defense system on cadmium accumulation

Cadmium (Cd) pollution is a serious threat to food safety and human health. Minimizing Cd uptake and enhancing Cd tolerance in plants are vital to improve crop yield and reduce hazardous effects to humans. In ...

Hongxing Chen, **aoyun Huang, Hui Chen, Song Zhang, Chengwu Fan… in Scientific Reports (2024)

Article

A non-invasive diagnostic nomogram for CHB-related early cirrhosis: a prospective study

This study aimed to construct a non-invasive diagnostic nomogram based on high-frequency ultrasound and magnetic resonance imaging results for early liver cirrhosis patients with chronic hepatitis B (CHB) whic...

Yuxia Chen, Meijuan Wei, Meng Chen, Chenyu Wu, Hongbing Ding… in Scientific Reports (2024)

Article

Unraveling distinct effects between CuO_x and PtCu alloy sites in Pt−Cu bimetallic catalysts for CO oxidation at different temperatures

In situ exploration of the dynamic structure evolution of catalysts plays a key role in revealing reaction mechanisms and designing efficient catalysts. In this work, PtCu/MgO catalysts, synthesized via the co...

Yunan Li, Lingling Guo, Meng Du, Chen Tian, Gui Zhao, Zhengwu Liu… in Nature Communications (2024)

Article

The value of right ventricular pulmonary artery coupling in determining the prognosis of patients with sepsis

The outcomes of patients with sepsis are influenced by the contractile function of the right ventricle (RV), but the impact of cardiopulmonary interaction in ICU-mortality of sepsis patients remains unclear. T...

Qiang Ma, Caiyun Ding, Wei Wei, Chencheng Su, Bozheng Li, Zihao Zhou… in Scientific Reports (2024)