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Ibrutinib modulates the immunosuppressive CLL microenvironment through STAT3-mediated suppression of regulatory B-cell function and inhibition of the PD-1/PD-L1 pathway

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  1. Article

    Open Access

    ATM function and its relationship with ATM gene mutations in chronic lymphocytic leukemia with the recurrent deletion (11q22.3-23.2)

    Approximately 10–20% of chronic lymphocytic leukemia (CLL) patients exhibit del(11q22–23) before treatment, this cohort increases to over 40% upon progression following chemoimmunotherapy. The coding sequence ...

    Y Jiang, H-C Chen, X Su, P A Thompson, X Liu, K-A Do, W Wierda… in Blood Cancer Journal (2016)

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  2. Article

    Open Access

    A reanalysis of cancer mortality in Canadian nuclear workers (1956–1994) based on revised exposure and cohort data

    A 15-country study of nuclear workers reported significantly increased radiation-related risks of all cancers excluding leukaemia, with Canadian data a major factor behind the pooled results. We analysed morta...

    L B Zablotska, R S D Lane, P A Thompson in British Journal of Cancer (2014)

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  3. Article

    Lymphoid Hyperplasia, CD45RBhigh to CD45RBlow T-cell imbalance, and suppression of Type I diabetes mellitus result from TNF blockade in NOD→NOD-scid adoptive T cell transfer

    Sustained antibody-mediated inhibition of tumor necrosis factor (TNF) activity offers protection against Type I (insulin-dependent) diabetes mellitus in non-obese diabetic (NOD) mice. The mechanism of this ef...

    G. R. Brown, M. D. Silva, P. A. Thompson, B. Beutler in Diabetologia (1998)

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  4. Article

    [Book Reviews]

    Pollen Physiology and Fertilization

    P. A. THOMPSON in Nature (1965)

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  5. Article

    Plant Phenolics

    Methods in Polyphenol Chemistry

    P. A. THOMPSON in Nature (1965)

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