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Article
Open AccessSpectrum of severity of multisystem inflammatory syndrome in children: an EHR-based cohort study from the RECOVER program
Multi-system inflammatory syndrome in children (MIS-C) is a severe post-acute sequela of SARS-CoV-2 infection in children, and there is a critical need to unfold its highly heterogeneous disease patterns. Our ...
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Article
Open AccessElectronic health records identify timely trends in childhood mental health conditions
Electronic health records (EHRs) data provide an opportunity to collect patient information rapidly, efficiently and at scale. National collaborative research networks, such as PEDSnet, aggregate EHRs data acr...
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Article
Does Living near Trees and Other Vegetation Affect the Contemporaneous Odds of Asthma Exacerbation among Pediatric Asthma Patients?
Vegetation may influence asthma exacerbation through effects on aeroallergens, localized climates, air pollution, or children’s behaviors and stress levels. We investigated the association between residential ...
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Article
Antibiotics prior to age 2 years have limited association with preschool growth trajectory
Prior studies of early antibiotic use and growth have shown mixed results, primarily on cross-sectional outcomes. This study examined the effect of oral antibiotics before age 24 months on growth trajectory at...
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Article
Open AccessAn efficient and accurate distributed learning algorithm for modeling multi-site zero-inflated count outcomes
Clinical research networks (CRNs), made up of multiple healthcare systems each with patient data from several care sites, are beneficial for studying rare outcomes and increasing generalizability of results. W...
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Article
Open AccessHumeral shaft fractures: national trends in management
The incidence of humeral shaft fractures has been increasing over time. This represents a growing public health concern in a climate of cost containment. The purpose of this study is to analyze national trends...
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Article
A prospective randomized trial comparing the effectiveness of one versus two (staged) corticosteroid injections for the treatment of stenosing tenosynovitis
Stenosing tenosynovitis or trigger finger is a common clinical condition regularly treated with steroid injections. Varied success is reported at early time points following injection. We present a prospective...
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Article
Open AccessThe epidemiology, risk factors, and impact on hospital mortality of status epilepticus after subdural hematoma in the United States
Subdural hematoma (SDH) is a well described risk factor in the development of Status Epilepticus (SE), however the epidemiology of SE after SDH is unknown. In this study, we sought to determine the epidemiolog...
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Article
Pattern of impact of femoroacetabular im**ement upon health-related quality of life: the determinant role of extra-articular factors
Despite the interest in surgical treatment of femoroacetabular im**ement (FAI), its impact upon health-related quality of life (HRQoL) has not been established. The objectives of this study were twofold: (a)...
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Article
Prevalence, timing, risk factors, and mechanisms of anterior cerebral artery infarctions following subarachnoid hemorrhage
Anterior cerebral artery (ACA) ischemia may be underdiagnosed following subarachnoid hemorrhage (SAH). The purpose of this study is to characterize the prevalence, timing, and risk factors for ACA infarction, ...
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Article
Impact of Intraventricular Hemorrhage upon Intracerebral Hematoma Expansion
The purpose of this study is to determine whether intraventricular hemorrhage (IVH) exerts a “decompressive” effect that limits intracerebral hemorrhage (ICH) enlargement.
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Article
Role of Antiplatelet Agents in Hematoma Expansion During The Acute Period of Intracerebral Hemorrhage
Oral anticoagulants have been associated with greater hematoma expansion in patients with intracerebral hemorrhage (ICH). The purpose of this study was to determine whether the reported use of antiplatelet age...