209 Result(s)
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Article
Genome editing of RICE FLOWERING LOCUS T 1 promoter delayed flowering in rice
The heading date of rice is a crucial agronomic traits affecting regional adaptation and grain productivity. Manipulating the vegetative growth period or delaying flowering can increase the yield and quality. ...
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Open AccessGenomic investigation of Salmonella enterica Serovar Welikade from a pediatric diarrhea case first time in Shanghai, China
Salmonella, an important foodborne pathogen, was estimated to be responsible for 95.1 million cases and 50,771 deaths worldwide. Sixteen serovars were responsible for approximately 80% of Salmonella infections in...
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Open AccessAngiopoietin-like protein 2 inhibits thrombus formation
Acute myocardial infarction is mainly caused by a lack of blood flood in the coronary artery. Angiopoietin-like protein 2 (ANGPTL2) induces platelet activation and thrombus formation in vitro through binding w...
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Article
Mammalian IRE1α dynamically and functionally coalesces with stress granules
Upon endoplasmic reticulum (ER) stress, activation of the ER-resident transmembrane protein kinase/endoribonuclease inositol-requiring enzyme 1 (IRE1) initiates a key branch of the unfolded protein response (U...
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Genome-wide identification of thaumatin-like protein family in pear and functional analysis their roles in pollen growth
Thaumatin-like proteins (TLPs) are crucial for plant growth and development. However, the function of TLPs in pear pollen tube growth has not been fully elucidated. In this study, we characterized 40 PbrTLPs with...
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Comprehensive analysis of stress-activated protein kinase genes (OsSAPKs) in rice flowering time
The rice SnRK2 members SAPK4, SAPK5, SAPK7 and SAPK10 are positive regulators involved in the regulation of rice flowering, while other single mutants exhibited no effect on rice flowering.
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A novel functional allele of Ehd3 controls flowering time in rice
Rice flowering time determines its geographical distribution and yield traits. As a short-day plant, rice can grow in the northern long-day conditions due to the functional mutations of many photosensitive gen...
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Open AccessCorrection: Kinome and phosphoproteome reprogramming underlies the aberrant immune responses in critically ill COVID-19 patients
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Open AccessPopulation genetic analyses highlight an eastward dispersal of Puccinia striiformis f. sp. tritici from the Shaanxi province to the North China Plain
Wheat stripe rust, caused by Puccinia striiformis f. sp. tritici (Pst), is a common airborne wheat disease. The frequent occurrence at a large scale in China has caused significant yield losses and poses a consid...
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Open AccessThe maize ZmCPK39-ZmKnox2 module regulates plant height
Plant height is an important agronomic trait that affects high-density tolerance and lodging resistance. However, the regulators and their underlying molecular mechanisms controlling plant height in maize rema...
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Inundation depth controls leaf photosynthetic capacity by regulating leaf area and N content in an estuarine wetland
Estuarine wetlands are important carbon sinks, with plant photosynthesis being a vital component of this process. Changes in the inundation depth of wetlands could alter leaf photosynthesis and thus ecosystem ...
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Open AccessResistant starch intake facilitates weight loss in humans by resha** the gut microbiota
Emerging evidence suggests that modulation of gut microbiota by dietary fibre may offer solutions for metabolic disorders. In a randomized placebo-controlled crossover design trial (ChiCTR-TTRCC-13003333) in 3...
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Open AccessKinome and phosphoproteome reprogramming underlies the aberrant immune responses in critically ill COVID-19 patients
SARS-CoV-2 infection triggers extensive host immune reactions, leading to severe diseases in certain individuals. However, the molecular basis underlying the excessive yet non-productive immune responses in se...
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Article
Open AccessA genome-wide association study reveals the relationship between human genetic variation and the nasal microbiome
The nasal cavity harbors diverse microbiota that contributes to human health and respiratory diseases. However, whether and to what extent the host genome shapes the nasal microbiome remains largely unknown. H...
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Open AccessIntegrated analysis of HSP20 genes in the develo** flesh of peach: identification, expression profiling, and subcellular localization
Plant HSP20s are not only synthesized in response to heat stress but are also involved in plant biotic and abiotic stress resistance, normal metabolism, development, differentiation, survival, ripening, and de...
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OsMAPK6 positively regulates rice cold tolerance at seedling stage via phosphorylating and stabilizing OsICE1 and OsIPA1
Rice is a chilling-sensitive plant, and extremely low temperatures seriously decrease rice production. Several genes involved in chilling stress have been reported in rice; however, the chilling signaling in r...
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Curculigoside attenuates osteoporosis through regulating DNMT1 mediated osteoblast activity
This work aims to study the function of curculigoside in osteoporosis and explore whether DNMT1 is closely involved in osteoblast activity. After OB-6 osteoblasts were treated with hydrogen peroxide (H2O2), a cur...
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Open AccessOutlining cardiac ion channel protein interactors and their signature in the human electrocardiogram
Protein–protein interactions are essential for normal cellular processes and signaling events. Defining these interaction networks is therefore crucial for understanding complex cellular functions and interpre...
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Pseudo-chromosome—length genome assembly for a deep-sea eel Ilyophis brunneus sheds light on the deep-sea adaptation
High hydrostatic pressure, low temperature, and scarce food supply are the major factors that limit the survival of vertebrates in extreme deep-sea environments. Here, we constructed a high-quality genome of t...
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Open AccessPathway and mechanism of tubulin folding mediated by TRiC/CCT along its ATPase cycle revealed using cryo-EM
The eukaryotic chaperonin TRiC/CCT assists the folding of about 10% of cytosolic proteins through an ATP-driven conformational cycle, and the essential cytoskeleton protein tubulin is the obligate substrate of...
