10 Result(s)

Article

Maternal educational attainment in pregnancy and epigenome-wide DNA methylation changes in the offspring from birth until adolescence

Maternal educational attainment (MEA) shapes offspring health through multiple potential pathways. Differential DNA methylation may provide a mechanistic understanding of these long-term associations. We aimed...

Priyanka Choudhary, Giulietta S. Monasso, Ville Karhunen… in Molecular Psychiatry (2024)

Article

Cord blood epigenome-wide meta-analysis in six European-based child cohorts identifies signatures linked to rapid weight growth

Rapid postnatal growth may result from exposure in utero or early life to adverse conditions and has been associated with diseases later in life and, in particular, with childhood obesity. DNA methylation, interf...

Rossella Alfano, Daniela Zugna, Henrique Barros, Mariona Bustamante… in BMC Medicine (2023)

Article

Cord blood metabolites and rapid postnatal growth as multiple mediators in the prenatal propensity to childhood overweight

The mechanisms underlying childhood overweight and obesity are poorly known. Here, we investigated the direct and indirect effects of different prenatal exposures on offspring rapid postnatal growth and overwe...

Rossella Alfano, Michelle Plusquin, Oliver Robinson… in International Journal of Obesity (2022)

Article

Cord blood metabolic signatures predictive of childhood overweight and rapid growth

Metabolomics may identify biological pathways predisposing children to the risk of overweight and obesity. In this study, we have investigated the cord blood metabolic signatures of rapid growth in infancy and...

Evangelos Handakas, Pekka Keski-Rahkonen, Lida Chatzi… in International Journal of Obesity (2021)

Article

Lower iodine storage in the placenta is associated with gestational diabetes mellitus

The micronutrient iodine is essential for a healthy intrauterine environment and is required for optimal fetal growth and neurodevelopment. Evidence linking urinary iodine concentrations, which mainly reflects...

Kristof Y. Neven, Bianca Cox, Charlotte Cosemans, Wilfried Gyselaers… in BMC Medicine (2021)

Article

Children’s microvascular traits and ambient air pollution exposure during pregnancy and early childhood: prospective evidence to elucidate the developmental origin of particle-induced disease

Particulate matter exposure during in utero life may entail adverse health outcomes later in life. The microvasculature undergoes extensive, organ-specific prenatal maturation. A growing body of evidence shows th...

Leen J. Luyten, Yinthe Dockx, Eline B. Provost, Narjes Madhloum… in BMC Medicine (2020)

Article

Telomere tracking from birth to adulthood and residential traffic exposure

Telomere attrition is extremely rapid during the first years of life, while lifestyle during adulthood exerts a minor impact. This suggests that early life is an important period in the determination of telome...

Esmée M. Bijnens, Maurice P. Zeegers, Catherine Derom, Dries S. Martens… in BMC Medicine (2017)

Article

Maternal pre-pregnancy body mass index and newborn telomere length

Newborn telomere length sets telomere length for later life. At birth, telomere length is highly variable among newborns and the environmental factors during in utero life for this observation remain largely unid...

Dries S. Martens, Michelle Plusquin, Wilfried Gyselaers, Immaculata De Vivo… in BMC Medicine (2016)

Article

Altered neonatal cord blood oxylipidome in association with exposure to particulate matter in the early life environment

Dries Martens, Sandra Gouveia-Figueira, Narjes Madhloum… in Archives of Public Health (2015)