7 Result(s)
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Article
Martin Lacher
Medicine/Public Health, general
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Article
Experimental congenital diaphragmatic hernia features an alteration of DNA sensing targets cGAS and STING
The pathogenesis of congenital diaphragmatic hernia (CDH) depends on multiple factors. Activation of the DNA-sensing cyclic-GMP-AMP-synthase (cGAS) and Stimulator-of-Interferon-Genes (STING) pathway by double-...
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Article
Open AccessCourse of an unplanned and unexpected pregnancy in a 39 year-old patient with Complex bladder extrophy: a case report
With improved operative techniques pregnancy rates have been rising in patients with anomalies of the extrophy-epispadias-complex, including also female patients with bladder extrophy. Specific risks around pr...
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Article
Open AccessDevelopment of an international core outcome set for treatment trials in necrotizing enterocolitis—a study protocol
Necrotizing enterocolitis (NEC) is the most lethal disease of the gastrointestinal tract of preterm infants. New and existing management strategies need clinical evaluation. Large heterogeneity exists in the s...
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Langzeitmorbidität und Transition von Kindern mit Ösophagusatresie
Fast täglich wird in Deutschland ein Kind mit Ösophagusatresie (ÖA) geboren. Die Gesamtüberlebensrate hat sich in den letzten Jahrzehnten signifikant verbessert. Auch nach einer erfolgreichen Operation haben P...
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Open AccessSurgical treatment of esophageal atresia with lower tracheoesophageal fistula in an extremely preterm infant (510 g, 25 + 5 weeks): a case report
The surgical management of esophageal atresia in extreme-low-birth-weight infants (< 1000 g) is challenging. We report on an extreme-low-birth-weight infant who was extremely preterm (510 g, 25 + 5 weeks) and ...
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Article
Prenatal maternal biomarkers for the early diagnosis of congenital malformations: A review
Congenital anomalies cause ~7% of all neonatal deaths, many of which have no identified pathophysiological cause. Because accurate and robust laboratory tests are unavailable for most birth defects, physicians...
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Article
The viral dsRNA analogue poly (I:C) induces necrotizing enterocolitis in neonatal mice
Necrotizing enterocolitis (NEC) is a life-threatening gastrointestinal disease in premature infants with high mortality and morbidity with uncertain pathogenesis. Recent research focused on the role of intralu...
