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  1. No Access

    Article

    Experimental congenital diaphragmatic hernia features an alteration of DNA sensing targets cGAS and STING

    The pathogenesis of congenital diaphragmatic hernia (CDH) depends on multiple factors. Activation of the DNA-sensing cyclic-GMP-AMP-synthase (cGAS) and Stimulator-of-Interferon-Genes (STING) pathway by double-...

    Moritz Markel, Wai Hei Tse, Nolan De Leon, Marietta Jank… in Pediatric Research (2024)

  2. No Access

    Article

    The RNA-binding protein quaking is upregulated in nitrofen-induced congenital diaphragmatic hernia lungs at the end of gestation

    The RNA-binding protein Quaking (QKI) increases during epithelial-to-mesenchymal transition and its expression is controlled by microRNA-200 family members. Here, we aimed to describe the expression of QKI in ...

    Yuichiro Miyake, Dustin Ameis, Wai Hei Tse, Daywin Patel… in Pediatric Surgery International (2024)

  3. No Access

    Article

    The effect of tracheal occlusion in congenital diaphragmatic hernia in the nitrofen rat lung explant model

    Here, we establish a tracheal occlusion (TO) model with rat lung explants in nitrofen-induced pulmonary hypoplasia in the congenital diaphragmatic hernia (CDH).

    Yuichiro Miyake, Wai Hei Tse, Jia Qi Wang, Nolan De Leon… in Pediatric Surgery International (2022)

  4. No Access

    Article

    Tenascin C is dysregulated in hypoplastic lungs of miR-200b−/− mice

    We previously demonstrated that absence of miR-200b results in abnormal lung development in congenital diaphragmatic hernia due to imbalance between epithelial and mesenchymal cells. Tenascin C is a highly con...

    Moritz Markel, Wai Hei Tse, Nolan DeLeon, Daywin Patel… in Pediatric Surgery International (2022)

  5. No Access

    Article

    First steps in the development of a liquid biopsy in situ hybridization protocol to determine circular RNA biomarkers in rat biofluids

    Epigenetic factors are involved in the pathogenesis of congenital diaphragmatic hernia (CDH). Circular RNAs (circRNAs) are epigenetic regulators amenable to biomarker profiling. Here, we aimed to develop a liq...

    Eimear Kirby, Wai Hei Tse, Daywin Patel, Richard Keijzer in Pediatric Surgery International (2019)

  6. No Access

    Article

    Prenatal maternal biomarkers for the early diagnosis of congenital malformations: A review

    Congenital anomalies cause ~7% of all neonatal deaths, many of which have no identified pathophysiological cause. Because accurate and robust laboratory tests are unavailable for most birth defects, physicians...

    Richard Wagner, Wai Hei Tse, Jan-Hendrik Gosemann, Martin Lacher… in Pediatric Research (2019)

  7. Article

    Open Access

    Deposition of Antibody Modified Upconversion Nanoparticles on Glass by a Laser-Assisted Method to Improve the Performance of Cell Culture

    A suitable surface is vital for maintaining or even promoting cells’ function and communication. Recently, studies show that nanostructured coatings could have a potential in improving cell adhesion. However, ...

    Songlin Yang, Wai Hei Tse, ** Zhang in Nanoscale Research Letters (2019)

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  8. Article

    Open Access

    Ag nanoparticles-decorated ZnO nanorod array on a mechanical flexible substrate with enhanced optical and antimicrobial properties

    Heteronanostructured zinc oxide nanorod (ZnO NR) array are vertically grown on polydimethylsiloxane (PDMS) through a hydrothermal method followed by an in situ deposition of silver nanoparticles (Ag NPs) through ...

    Yi Chen, Wai Hei Tse, Longyan Chen, ** Zhang in Nanoscale Research Letters (2015)

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