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Article
8th International AEK Symposium of the Division of Experimental Cancer Research of the German Cancer Society
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Article
Contribution of specific DNA repair pathways to the chemoresistance of human lymphocytes to alkylating drugs
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Article
Two-step radioimmunotherapy for myeloablation prior to bone marrow transplantation
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Article
Development of monoclonal antibodies for the sensitive detection and quantification of specific DNA lesions
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Article
Overall and gene-specific repair of DNAO-alkylation products: Relevance for mutagenesis and carcinogenic risk
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Article
Design of tailor-made prodrugs for tumor-selective therapy
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Article
A monoclonal antibody for two-step myeloablative radioimmunotherapy prior to bone marrow transplantation in dogs
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Article
Physical and biochemical properties of the human DNA repair protein O6-alkylguanine-DNA alkyl-transferase (AT)
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Article
Absract
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Article
Scientific Proceedings Fifth Symposium of the Section of Experimental Cancer Research (SEK) of the German Cancer Society
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Article
Immuno-slot-blot: A highly sensitive immunoassay for the quantitation of carcinogen-modified nucleosides in DNA
We have established a highly sensitive immuno-slot-blot (ISB) procedure that can be routinely applied for detection and quantitation of any heat- or alkali-stable structural DNA modification (caused by carcino...
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Article
Antibodies specific for DNA components structurally modified by chemical carcinogens
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Article
Introduction
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Article
Phenotypic properties of neoplastic cell lines developed from fetal rat brain cells in culture after exposure to ethylnitrosourea in vivo
We have recently reported that fetal BD IX-rat brain cells (FBC), transferred to long-term culture after a transplacental pulse of EtNU on the 18th day of gestation, undergo neoplastic transformation in vitro ...
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Article
Molecular and cellular mechanisms associated with pulse-carcinogenesis in the rat nervous system by ethylnitrosourea: ethylation of nucleic acids and elimination rates of ethylated bases from the DNA of different tissues
The ethylation of nucleic acids by the nervous system-specific pulse-carcinogen N-ethyl-N-nitrosourea (ENU) was investigated in different tissues of the fetal, 10-day-old, and adult BD IX rat, and compared with d...
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Article
Proliferative parameters of mammalian cell systems and their rôle in tumor growth and carcinogenesis
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Article
Untersuchungen zur Synchronisation in vivo: Temporäre Inhibition der DNA-Synthese durch Hydroxyharnstoff in normalen und malignen Säugerzellsystemen
The synchronous passage of proliferating cells through defined phases of the cell cycle is a prerequisite for the study of a number of problems associated with carcinogenesis and cancer therapy. It is particul...
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Article
Zur RNA-Synthese im Verlauf der Lebercarcinogenese durch Diäthylnitrosamin
The incorporation of 3H-cytidine (RNA synthesis) into liver explants under standardized in vitro conditions was measured during hepatocarcinogenesis by continuous oral administration of diethylnitrosamine (DENA) ...