2,544 Result(s)

Article

Carbon-ion radiotherapy alone vs. standard dose photon radiation with carbon-ion radiotherapy boost for high-grade gliomas: a retrospective study

This study aimed to compare the survival outcome and side effects in patients with primary high-grade glioma (HGG) who received carbon ion radiotherapy (CIRT) alone or as a boost strategy after photon radiatio...

**aoJun Li, YanShan Zhang, YanCheng Ye, SuQing Tian, TingChao Hu, HongYu Chai… in BMC Cancer (2024)

Article

Investigating distinct clinical features and constructing a nomogram model for survival probability in adults with cerebellar high-grade gliomas

The clinical features of cerebellar high-grade gliomas (cHGGs) in adults have not been thoroughly explored. This large-scale, population-based study aimed to comprehensively outline these traits and construct ...

Tao Chang, Rui Zhang, Jiahao Gan, Yuan Yang, Yanhui Liu, Yan Ju, **aodong Niu… in BMC Cancer (2024)

Article

Nomogram for predicting the probability of rectal anastomotic re-leakage after stoma closure: a retrospective study

In this study, we aimed to identify the risk factors in patients with rectal anastomotic re-leakage and develop a prediction model to predict the probability of rectal anastomotic re-leakage after stoma closure.

Yuegang Li, Gang Hu, **zhu Zhang, Wenlong Qiu, Shiwen Mei, **shan Wang… in BMC Cancer (2024)

Article

eHSP90α in front-line therapy in EGFR exon 19 deletion and 21 Leu858Arg mutations in advanced lung adenocarcinoma

Extracellular heat shock protein 90 AA1(eHSP90α) is intricately linked to tumor progression and prognosis. This study aimed to investigate the difference in the value of eHSP90α in post-treatment response asse...

Yingzhen Bian, Haizhou Liu, **glei Huang, Zhaorong Feng, Yanyan Lin… in BMC Cancer (2024)

Article

Correction: Apatinib combined with temozolomide in diffuse midline glioma: a novel and effective therapy

Yu-An Li, Chuan Zhao, **g-**g Ge, Cheng Li, Feng-Jun Xue, Shao-Pei Qi… in BMC Cancer (2024)

Article

Impact of baseline body composition on prognostic outcomes in urological malignancies treated with immunotherapy: a pooled analysis of 10 retrospective studies

Numerous epidemiological investigations have explored the impact of body composition on the effectiveness of immune checkpoint inhibitors (ICIs) in urological malignancies (UM) patients, yielding conflicting f...

Wangbin Ma, Qiao Shi, Lilong Zhang, Zhendong Qiu, Tianrui Kuang… in BMC Cancer (2024)

Article

Recursive partitioning analysis for survival stratification and early imaging prediction of molecular biomarker in glioma patients

Glioma is the most common primary brain tumor with high mortality and disability rates. Recent studies have highlighted the significant prognostic consequences of subty** molecular pathological markers using...

**an **e, Chen Luo, Shuai Wu, Wanyu Qiao, Wei Deng, Lei **, Junfeng Lu… in BMC Cancer (2024)

Article

Selective anti-tumor activity of glutathione-responsive abasic site trap** agent in anaplastic thyroid carcinoma

Anaplastic thyroid carcinoma (ATC) is a rare but highly aggressive thyroid cancer with poor prognosis. Killing cancer cells by inducing DNA damage or blockage of DNA repair is a promising strategy for chemothe...

**yan Chai, Mengxue Su, Ruiguo Zhang, Ning Li, Yuanyuan Jia, Wei Zheng… in BMC Cancer (2024)

Article

Clinical applications of telemedicine services using a regional telemedicine platform for cancer treatment: a cross-sectional study

Telemedicine is beneficial for improving treatment efficiency and reducing medical expenses of cancer patients. This study focuses on cancer patients participating in teleconsultations through a regional telem...

Fangfang Cui, Xu Zhang, **anying He, Dongqing Liu, **ming Shi, Ming Ye… in BMC Cancer (2024)

Article

Exploring the causal association between uric acid and lung cancer in east Asian and European populations: a mendelian randomization study

Lung cancer still ranks first in the mortality rate of cancer. Uric acid is a product of purine metabolism in humans. Its presence in the serum is controversial; some say that its high levels have a protective...

** Lin, Linxiang Zhang, **aohui Tang, Jihuang Wang in BMC Cancer (2024)

Article

Differentiation of glioma and solitary brain metastasis: a multi-parameter magnetic resonance imaging study using histogram analysis

Differentiation of glioma and solitary brain metastasis (SBM), which requires biopsy or multi-disciplinary diagnosis, remains sophisticated clinically. Histogram analysis of MR diffusion or molecular imaging h...

Yifei Su, Rui Cheng, **xia Guo, Miaoqi Zhang, Junhao Wang, Hongming Ji… in BMC Cancer (2024)

Article

Establishment and characterization of a novel multidrug-resistant pancreatic ductal adenocarcinoma cell line, PDAC-X1

Drug resistance remains a significant challenge in the treatment of pancreatic cancer. The development of drug-resistant cell lines is crucial to understanding the underlying mechanisms of resistance and devel...

Cheng Yu, Yuanhui Su, **n Miao, Changpeng Chai, Huan Tang, Lu Li, Jianfeng Yi… in BMC Cancer (2024)

Article

Promoter profiles in plasma CfDNA exhibits a potential utility of predicting the efficacy of neoadjuvant chemotherapy in breast cancer patients

Gene expression profiles in breast tissue biopsies contain information related to chemotherapy efficacy. The promoter profiles in cell-free DNA (cfDNA) carrying gene expression information of the original tiss...

Xu Yang, Qing Liu, Zhiwei Guo, Xuexi Yang, Kun Li, Bowei Han… in Breast Cancer Research (2024)

Article

Androgen receptor-mediated pharmacogenomic expression quantitative trait loci: implications for breast cancer response to AR-targeting therapy

Endocrine therapy is the most important treatment modality of breast cancer patients whose tumors express the estrogen receptor α (ERα). The androgen receptor (AR) is also expressed in the vast majority (80–90...

Huanyao Gao, Lixuan Wei, Shreya Indulkar, Thanh Thanh. L. Nguyen… in Breast Cancer Research (2024)

Article

Functions of methyltransferase-like 3 in breast cancer: pathogenesis, drug resistance, and therapeutic target

Breast cancer (BC) is a highly prevalent malignancy worldwide, with complex pathogenesis and treatment challenges. Research reveals that methyltransferase-like 3 (METTL3) is widely involved in the pathogenesis...

Dongqiong **ao, Mingfu Zhang, Yi Qu, **aojuan Su in Breast Cancer Research (2024)

Article

Association of effective dose to immune cells and vertebral marrow dose with hematologic toxicity during neoadjuvant chemoradiotherapy in esophageal squamous cell carcinoma

To explore the correlation between effective dose to immune cells (EDIC) and vertebral bone marrow dose and hematologic toxicity (HT) for esophageal squamous cell carcinoma (ESCC) during neoadjuvant chemoradio...

Meng Zhang, Zhenjiang Li, Yong Yin in BMC Cancer (2024)

Article

The predictive value of serum inflammatory markers for the severity of cervical lesions

Exploring the predictive value of NLR, PLR, MLR, and SII for the severity of cervical cancer screening abnormalities in patients.

Lin Qin, Lina Zhang in BMC Cancer (2024)

Article

MTF1 genetic variants are associated with lung cancer risk in the Chinese Han population

Metal-regulatory transcription factor 1 (MTF1), a conserved metal-binding transcription factor in eukaryotes, regulates the proliferation of cancer cells by activating downstream target genes and then particip...

Yu**g Cheng, Chan Zhang, Qi Li, **n Yang, Wanlu Chen, KunHua He… in BMC Cancer (2024)

Article

System-wide identification of novel de-ubiquitination targets for USP10 in gastric cancer metastasis through multi-omics screening

Ubiquitin-specific peptidase 10 (USP10), a typical de-ubiquitinase, has been found to play a double-edged role in human cancers. Previously, we reported that the expression of USP10 was negatively correlated w...

Zhi Zeng, Yina Li, Heng Zhou, Mingyang Li, Juan Ye, Dan Li, Yuxi Zhu… in BMC Cancer (2024)

Article

LMO family gene polymorphisms and Wilms tumor susceptibility in Chinese children: a five-center case-control study

Wilms tumor is the most prevalent embryonal kidney malignancy in children worldwide. Previous genome-wide association study (GWAS) identified that LIM domain only 1 (LMO1) gene polymorphisms affected the suscepti...

Wen Fu, Linqing Deng, **aosong Yan, Rui-** Hua, Jiao Zhang, Haixia Zhou… in BMC Cancer (2024)