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    Article

    Genome-wide association study on detailed profiles of smoking behavior and nicotine dependence in a twin sample

    Smoking is a major risk factor for several somatic diseases and is also emerging as a causal factor for neuropsychiatric disorders. Genome-wide association (GWA) and candidate gene studies for smoking behavior...

    A Loukola, J Wedenoja, K Keskitalo-Vuokko, U Broms, T Korhonen… in Molecular Psychiatry (2014)

  2. Article

    Evidence that BMI and type 2 diabetes share only a minor fraction of genetic variance: a follow-up study of 23,585 monozygotic and dizygotic twins from the Finnish Twin Cohort Study

    We investigated whether BMI predicts type 2 diabetes in twins and to what extent that is explained by common genetic factors.

    M. Lehtovirta, K. H. Pietiläinen, E. Levälahti, K. Heikkilä, L. Groop… in Diabetologia (2010)

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    Replication of linkage on chromosome 7q22 and association of the regional Reelin gene with working memory in schizophrenia families

    Schizophrenia is a common and complex mental disorder. Hereditary factors are important for its etiology, but despite linkage signals reported to several chromosomal regions in different populations, final ide...

    J Wedenoja, A Loukola, A Tuulio-Henriksson, T Paunio, J Ekelund… in Molecular Psychiatry (2008)

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    Article

    Linkage of nicotine dependence and smoking behavior on 10q, 7q and 11p in twins with homogeneous genetic background

    The significant worldwide health burden introduced by tobacco smoking highlights the importance of studying the genetic determinants of smoking behavior and the key factor sustaining compulsive smoking, that i...

    A Loukola, U Broms, H Maunu, E Widén, K Heikkilä, M Siivola… in The Pharmacogenomics Journal (2008)