53 Result(s)
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Article
Jung Hwan Park
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Open AccessA study on the fabrication of metal microneedle array electrodes for ECG detection based on low melting point Bi–In–Sn alloys
This study describes the fabrication and characteristics of microneedle array electrodes (MAEs) using Bismuth–Indium–Tin (Bi–In–Sn) alloys. The MAEs consist of 57 pyramid-shaped needles measuring 340 μm wide a...
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Pharmaceutical and Immunological Evaluation of Cholera Toxin A1 Subunit as an Adjuvant of Hepatitis B Vaccine Microneedles
For successful delivery of a solid vaccine formulation into the skin using microneedles, the solubility of an adjuvant should be considered because the decrease in the dissolution rate by the addition of adjuv...
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Performance evaluation of carbon nanotube yarn-based inductors for ISM-frequency band soft-switching converters
With the advancement of carbon material science, there have been attempts to apply carbon nanotubes in various engineering fields. In power electronics, application research has been conducted on using carbon ...
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Incidence and risk factors of hypoparathyroidism and hypocalcemia after hemithyroidectomy
The incidence and risk factors for hypoparathyroidism after total thyroidectomy is well-known. However, the characteristics of hypoparathyroidism and hypocalcemia after hemithyroidectomy have not been investig...
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Open AccessFlash-Induced High-Throughput Porous Graphene via Synergistic Photo-Effects for Electromagnetic Interference Shielding
Flash-induced porous graphene (FPG) was synthesized via a broad-spectrum flash lamp that induced synergistic photo-effects between ultraviolet and visible-near-infrared wav...
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Data-Driven Methods for Predicting the State of Health, State of Charge, and Remaining Useful Life of Li-Ion Batteries: A Comprehensive Review
Lithium-ion batteries are widely used in electric vehicles, electronic devices, and energy storage systems owing to their high energy density, long life, and outstanding performance. However, various internal ...
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Open AccessSubaqueous 3D stem cell spheroid levitation culture using anti-gravity bioreactor based on sound wave superposition
Recently, various studies have revealed that 3D cell spheroids have several advantages over 2D cells in stem cell culture. However, conventional 3D spheroid culture methods have some disadvantages and limitati...
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Silica-Capped and Gold-Decorated Silica Nanoparticles for Enhancing Effect of Gold Nanoparticle-Based Photothermal Therapy
Various methods based on gold nanoparticles (AuNPs) have been applied to enhance the photothermal effect. Among these methods, combining gold nanoparticles and stem cells has been suggested as a new technique ...
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Open AccessAuthor Correction: Development of the H3N2 influenza microneedle vaccine for cross-protection against antigenic variants
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Open AccessSingle-cell transcriptomics reveal cellular diversity of aortic valve and the immunomodulation by PPARγ during hyperlipidemia
Valvular inflammation triggered by hyperlipidemia has been considered as an important initial process of aortic valve disease; however, cellular and molecular evidence remains unclear. Here, we assess the rela...
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Open AccessDevelopment of the H3N2 influenza microneedle vaccine for cross-protection against antigenic variants
Due to the continuously mutating nature of the H3N2 virus, two aspects were considered when preparing the H3N2 microneedle vaccines: (1) rapid preparation and (2) cross-protection against multiple antigenic va...
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The Relationship between the Drug Delivery Properties of a Formulation of Teriparatide Microneedles and the Pharmacokinetic Evaluation of Teriparatide Administration in Rats
Teriparatide is an effective drug for the treatment of osteoporosis. This study examines the relationship between the drug delivery properties of the solid formulation with teriparatide and the pharmacokinetic...
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Metal Ion Releasing Gold Nanoparticles for Improving Therapeutic Efficiency of Tumor Targeted Photothermal Therapy
Owing to the tumor-targeted migration capacity of human mesenchymal stem cells (hMSCs), they have been combined with nanoparticles for photothermal therapy. However, the low viability of hMSCs following transp...
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Microneedle technologies
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Preparation and evaluation of rapid disintegrating formulation from coated microneedle
Microneedles (MNs), one of the transdermal drug delivery systems, have received extensive interest as an alternative to parenteral or parenteral administrations. For the successful drug delivery of coated MNs,...
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Ovalbumin and cholera toxin delivery to buccal mucus for immunization using microneedles and comparison of immunological response to transmucosal delivery
The oral mucosa is an effective site for vaccination. However, for oral mucosal vaccines, delivery of the right dose of vaccine is not possible due to the water-rich environment. In this study, the buccal muco...
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Epicutaneous Allergen Administration with Microneedles as a Novel Method of Immunotherapy for House Dust Mite (HDM) Allergic Rhinitis
Epicutaneous immunotherapy (EPIT) is being studied as a method for treating allergic rhinitis because of skin immunology, user convenience and enhanced patient compliance. However, the use of EPIT is limited b...
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Risk factors for hypothyroidism and thyroid hormone replacement after hemithyroidectomy in papillary thyroid carcinoma
Thyroid lobectomy is now preferred over total thyroidectomy to preserve thyroid function and reduce complications in patients with low-risk papillary thyroid carcinoma (PTC). One inevitable consequence of thyr...
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Non-steroidal anti-inflammatory drugs in patients with stable ankylosing spondylitis receiving tumor necrosis factor inhibitor: continued vs withdrawn
To investigate the effect of non-steroidal anti-inflammatory drugs (NSAIDs) on disease activity in patients with stable ankylosing spondylitis (AS) receiving tumor necrosis factor inhibitor (TNFi).
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Open AccessLaser-induced graphitization of polydopamine leads to enhanced mechanical performance while preserving multifunctionality
Polydopamine (PDA) is a simple and versatile conformal coating material that has been proposed for a variety of uses; however in practice its performance is often hindered by poor mechanical properties and hig...
