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Reply to: Retesting the influences of mutation accumulation and antagonistic pleiotropy on human senescence and disease

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  1. Article

    Open Access

    A multilayered post-GWAS assessment on genetic susceptibility to pancreatic cancer

    Pancreatic cancer (PC) is a complex disease in which both non-genetic and genetic factors interplay. To date, 40 GWAS hits have been associated with PC risk in individuals of European descent, explaining 4.1% ...

    Evangelina López de Maturana, Juan Antonio Rodríguez, Lola Alonso… in Genome Medicine (2021)

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  2. Article

    Open Access

    Combining Multiple Hypothesis Testing with Machine Learning Increases the Statistical Power of Genome-wide Association Studies

    The standard approach to the analysis of genome-wide association studies (GWAS) is based on testing each position in the genome individually for statistical significance of its association with the phenotype u...

    Bettina Mieth, Marius Kloft, Juan Antonio Rodríguez, Sören Sonnenburg… in Scientific Reports (2016)

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  3. Article

    Open Access

    Genomic analysis of the blood attributed to Louis XVI (1754–1793), king of France

    A pyrographically decorated gourd, dated to the French Revolution period, has been alleged to contain a handkerchief dipped into the blood of the French king Louis XVI (1754–1793) after his beheading but recen...

    Iñigo Olalde, Federico Sánchez-Quinto, Debayan Datta… in Scientific Reports (2014)

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