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  1. No Access

    Article

    Overexpression of ornithine decarboxylase suppresses thapsigargin-induced apoptosis

    Ornithine decarboxylase (ODC), the key enzyme of polyamine biosynthesis, has paradoxical roles in apoptosis. Our published papers show overexpression of ODC prevents the apoptosis induced by many cytotoxic dru...

    Wei-Chung Hsieh, Pei-Chen Hsu, Ya-Fan Liao, Shu-Ting Young… in Molecules and Cells (2010)

  2. No Access

    Article

    Zebrafish rgs4 is essential for motility and axonogenesis mediated by Akt signaling

    The schizophrenia susceptibility gene, Rgs4, is one of the most intensively studied regulators of G-protein signaling members, well known to be fundamental in regulating neurotransmission. However, little is know...

    Yi-Chuan Cheng, Paul J. Scotting, Li-Sung Hsu… in Cellular and Molecular Life Sciences (2013)

  3. Article

    Open Access

    Loss of fragile WWOX gene leads to senescence escape and genome instability

    Induction of DNA damage response (DDR) to ensure accurate duplication of genetic information is crucial for maintaining genome integrity during DNA replication. Cellular senescence is a DDR mechanism that prev...

    Hui-Ching Cheng, Po-Hsien Huang, Feng-Jie Lai… in Cellular and Molecular Life Sciences (2023)

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